Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Timothy D. O'Brien"'
Autor:
David J. Leishman, Scott H. Oppler, Laura L. Hocum Stone, Timothy D. O’Brien, Sabarinathan Ramachandran, Bradley J. Willenberg, Andrew B. Adams, Bernhard J. Hering, Melanie L. Graham
Publikováno v:
Frontiers in Transplantation, Vol 3 (2024)
IntroductionSuccessful diabetes reversal using pancreatic islet transplantation by various groups illustrates the significant achievements made in cell-based diabetes therapy. While clinically, intraportal islet delivery is almost exclusively used, i
Externí odkaz:
https://doaj.org/article/335e45c1fc714300bdfd3610c0c06ce1
Autor:
Samuel A. Einstein, Leah V. Steyn, Bradley P. Weegman, Thomas M. Suszynski, Athanassios Sambanis, Timothy D. O’Brien, Efstathios S. Avgoustiniatos, Meri T. Firpo, Melanie L. Graham, Jody Janecek, Lynn E. Eberly, Michael Garwood, Charles W. Putnam, Klearchos K. Papas
Publikováno v:
Frontiers in Transplantation, Vol 2 (2023)
IntroductionSubcutaneous macroencapsulation devices circumvent disadvantages of intraportal islet therapy. However, a curative dose of islets within reasonably sized devices requires dense cell packing. We measured internal PO2 of implanted devices,
Externí odkaz:
https://doaj.org/article/4d2c40b1f118487788b0c8b74419747e
Publikováno v:
BMC Medical Genomics, Vol 13, Iss S11, Pp 1-14 (2020)
Abstract Background Psychiatric disorders such as schizophrenia (SCZ), bipolar disorder (BIP), major depressive disorder (MDD), attention deficit-hyperactivity disorder (ADHD), and autism spectrum disorder (ASD) are often related to brain development
Externí odkaz:
https://doaj.org/article/35a1a46e443a4205af57500c05f2c728
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-14 (2018)
Abstract Background There are two main types of lung cancer: small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). NSCLC has many subtypes, but the two most common are lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC)
Externí odkaz:
https://doaj.org/article/d6ef1b18d2e24f189655691c7256daf5
Autor:
Haiyun Pei, Hsu-Yuan Fu, Hiroyuki Hirai, Dong Seong Cho, Timothy D. O'Brien, James Dutton, Catherine M. Verfaillie, Wei-Shou Hu
Publikováno v:
Stem Cell Research, Vol 21, Iss C, Pp 132-136 (2017)
We derived a stable cell line from Chinese hamster embryonic fibroblasts by transduction of four mouse transcription factors (M3O, Sox2, Klf4, and n-Myc) using a lentiviral vector. The cell line possess all the characteristics of an induced pluripote
Externí odkaz:
https://doaj.org/article/45107a916851422fa126eb3aa6ca581e
Autor:
Andrew T. Crane, Rajagopal N. Aravalli, Atsushi Asakura, Andrew W. Grande, Venkatramana D. Krishna, Daniel F. Carlson, Maxim C.-J. Cheeran, Georgette Danczyk, James R. Dutton, Perry B. Hackett, Wei-Shou Hu, Ling Li, Wei-Cheng Lu, Zachary D. Miller, Timothy D. O’Brien, Angela Panoskaltsis-Mortari, Ann M. Parr, Clairice Pearce, Mercedes Ruiz-Estevez, Maple Shiao, Christopher J. Sipe, Nikolas G. Toman, Joseph Voth, Hui Xie, Clifford J. Steer, Walter C. Low
Publikováno v:
Cell Transplantation, Vol 28 (2019)
Blastocyst complementation combined with gene editing is an emerging approach in the field of regenerative medicine that could potentially solve the worldwide problem of organ shortages for transplantation. In theory, blastocyst complementation can g
Externí odkaz:
https://doaj.org/article/0e597a7add9c43cfb591e8698243ec66
Publikováno v:
Veterinary Sciences, Vol 2, Iss 2, Pp 43-51 (2015)
The characteristics of canine IL-17-producing cells are incompletely understood. Expression of mRNA encoding orthologs of IL-17 and the IL-17 receptor has been documented in tissues from dogs with arthritis, inflammatory bowel disease, and lymphoma;
Externí odkaz:
https://doaj.org/article/12ac1ad544c94019aa9a981692aa67c3
Autor:
Bradley P. Weegman, Michael J. Taylor, Simona C. Baicu, Kate Mueller, Timothy D. O'brien, John Wilson, Klearchos K. Papas
Publikováno v:
Cell Transplantation, Vol 25 (2016)
Diabetes is a major health problem worldwide, and there is substantial interest in developing xenogeneic islet transplantation as a potential treatment. The potential to relieve the demand on an inadequate supply of human pancreata is dependent upon
Externí odkaz:
https://doaj.org/article/8e5582ddb99e4f4980a58708a72469f6
Autor:
Jaime F. Modiano, Irving L. Weissman, M. Gerard O'Sullivan, Timothy D. O'Brien, Ingrid Cornax, Kelly M. McKenna, Susan Prohaska, Amira Barkal, David Lowery, Sarah Rue, Jem Efe, Kristin Bloink, Aaron M. Ring, Hirotaka Tomiyasu, Peter J. Schnorr, Daisuke Ito, Katie L. Anderson, Kipp Weiskopf
1E4 antibody binds canine CD20 extracellular domain 2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a15c205800718db29fffa850b50309e0
https://doi.org/10.1158/2326-6066.22538005
https://doi.org/10.1158/2326-6066.22538005
Autor:
Jaime F. Modiano, Irving L. Weissman, M. Gerard O'Sullivan, Timothy D. O'Brien, Ingrid Cornax, Kelly M. McKenna, Susan Prohaska, Amira Barkal, David Lowery, Sarah Rue, Jem Efe, Kristin Bloink, Aaron M. Ring, Hirotaka Tomiyasu, Peter J. Schnorr, Daisuke Ito, Katie L. Anderson, Kipp Weiskopf
Supplementary Table S1. Similarity between CD47 variants across species. Supplementary Table S2. Similarity between SIRPα variants across species. Supplementary Table S3. Summary of tumor necrosis scores following treatment with the indicated therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0998af4d8c0fbbf81ba7e44f13fa3856
https://doi.org/10.1158/2326-6066.22537996
https://doi.org/10.1158/2326-6066.22537996