Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Timothy D. Morello"'
Autor:
Michael Van Meter, Matthew Simon, Gregory Tombline, Alfred May, Timothy D. Morello, Basil P. Hubbard, Katie Bredbenner, Rosa Park, David A. Sinclair, Vilhelm A. Bohr, Vera Gorbunova, Andrei Seluanov
Publikováno v:
Cell Reports, Vol 16, Iss 10, Pp 2641-2650 (2016)
The accumulation of damage caused by oxidative stress has been linked to aging and to the etiology of numerous age-related diseases. The longevity gene, sirtuin 6 (SIRT6), promotes genome stability by facilitating DNA repair, especially under oxidati
Externí odkaz:
https://doaj.org/article/12a6952e0c864aaebd0d90cd66cdd3b3
Autor:
Timothy D. Morello, Jun Wen Zhong, Melissa L. Conerly, Chao-Jen Wong, Amy E. Campbell, Silvère M. van der Maarel, Stephen J. Tapscott, Sean C. Shadle, Sujatha Jagannathan
Publikováno v:
PLoS Genetics, Vol 13, Iss 3, p e1006658 (2017)
PLoS Genetics, 13(3)
PLoS Genetics
PLoS Genetics, 13(3)
PLoS Genetics
Facioscapulohumeral dystrophy (FSHD) is caused by the mis-expression of DUX4 in skeletal muscle cells. DUX4 is a transcription factor that activates genes normally associated with stem cell biology and its mis-expression in FSHD cells results in apop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef452c827d7f8eb9a84a38fe2141212
http://europepmc.org/articles/PMC5362247?pdf=render
http://europepmc.org/articles/PMC5362247?pdf=render
Autor:
Michael Van Meter, Anthony J. Geneva, Sarallah Rezazadeh, Timothy D. Morello, Vera Gorbunova, Mehr Kashyap, Andrei Seluanov
Publikováno v:
Nature communications
L1 retrotransposons are an abundant class of transposable elements that pose a threat to genome stability and may have a role in age-related pathologies such as cancer. Recent evidence indicates that L1s become more active in somatic tissues during t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23e0a49f1a135b2c20cf6c9a69f412eb
https://pubmed.ncbi.nlm.nih.gov/25247314
https://pubmed.ncbi.nlm.nih.gov/25247314
Autor:
Sean C Shadle, Jun Wen Zhong, Amy E Campbell, Melissa L Conerly, Sujatha Jagannathan, Chao-Jen Wong, Timothy D Morello, Silvère M van der Maarel, Stephen J Tapscott
Publikováno v:
PLoS Genetics, Vol 13, Iss 3, p e1006658 (2017)
Facioscapulohumeral dystrophy (FSHD) is caused by the mis-expression of DUX4 in skeletal muscle cells. DUX4 is a transcription factor that activates genes normally associated with stem cell biology and its mis-expression in FSHD cells results in apop
Externí odkaz:
https://doaj.org/article/bb220183be2b4288ac3b9940563a76c0