Zobrazeno 1 - 10
of 330
pro vyhledávání: '"Timothy D. Mchugh"'
Autor:
Bugwesa Z. Katale, Sylvia Rofael, Linzy Elton, Erasto V. Mbugi, Stella G. Mpagama, Daphne Mtunga, Maryjesca G. Mafie, Peter M. Mbelele, Charlotte Williams, Happiness C. Mvungi, Rachel Williams, Gulinja A. Saku, Joanitha A. Ruta, Timothy D. McHugh, Mecky I. Matee
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 23, Iss 1, Pp 1-10 (2024)
Abstract Background Whole-genome sequencing (WGS)-based prediction of drug resistance in Mycobacterium tuberculosis has the potential to guide clinical decisions in the design of optimal treatment regimens. Methods We utilized WGS to investigate drug
Externí odkaz:
https://doaj.org/article/d198dc7b488e4a8689c23e834a7f6c50
Autor:
Eskild Petersen, Linzy Elton, Najmul Haider, Timothy D. McHugh, Osman Dar, Avinash Sharma, Pam Luka, Tieble Traore, Edgar Simulundu, Esam I. Azhar, Francine Ntoumi, Moses J. Bockarie, Ziad A. Memish, Alimuddin Zumla
Publikováno v:
International Journal of Infectious Diseases, Vol 148, Iss , Pp 107216- (2024)
Externí odkaz:
https://doaj.org/article/88d852445c9d4b3384a8f406a1fc2f1d
Autor:
Antony M. Rapulana, Thabo Mpotje, Omolara O. Baiyegunhi, Hlumani Ndlovu, Theresa K. Smit, Timothy D. McHugh, Mohlopheni J. Marakalala
Publikováno v:
Frontiers in Molecular Medicine, Vol 4 (2024)
Background: Accurate diagnosis of latent tuberculosis infected (LTBI) individuals is important in identifying individuals at risk of developing active tuberculosis. Current diagnosis of LTBI routinely relies on the detection and measurement of immune
Externí odkaz:
https://doaj.org/article/41a6b4e68deb442e8954feea036eb39b
Autor:
Mehmood Qadir, Rani Faryal, Muhammad Tahir Khan, Sajjad Ahmed Khan, Shulin Zhang, Weimin Li, Dong Qing Wei, Sabira Tahseen, Timothy D. McHugh
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 1 (2024)
ABSTRACT The World Health Organization recommends culture-based techniques as the gold standard for rifampicin-resistant (RR) tuberculosis. However, as rapid molecular assays are rolled out, discordance in resistance has been observed. The current st
Externí odkaz:
https://doaj.org/article/a4482b5a420d4e689fd65abddf94e9b0
Autor:
Eskild Petersen, David S. Hui, Jean B. Nachega, Francine Ntoumi, Delia Goletti, Eleni Aklillu, Avinash Sharma, Thomas Nyirenda, Dorothy Yeboah-Manu, Giovanni Satta, Christopher da Costa, Esam I. Azhar, Moses Bockarie, Seif Al-Abri, Timothy D. McHugh, Alfonso J. Rodriguez-Morales, George M Varghese, Alimuddin Zumla
Publikováno v:
International Journal of Infectious Diseases, Vol 131, Iss , Pp 180-182 (2023)
Externí odkaz:
https://doaj.org/article/c61802f9fe4a4b73afdb034801dd70d2
Autor:
Frank Kloprogge, Julio Ortiz Canseco, Lynette Phee, Zahra Sadouki, Karin Kipper, Adam A. Witney, Neil Stoker, Timothy D. McHugh
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Concentration dependency of phenotypic and genotypic isoniazid-rifampicin resistance emergence was investigated to obtain a mechanistic understanding on how anti-mycobacterial drugs facilitate the emergence of bacterial populations that surv
Externí odkaz:
https://doaj.org/article/2dfb2ec4555549a59862ee240fc1fb9e
Autor:
Eloise J. Busby, Ronan M. Doyle, Clara Leboreiro Babe, Kathryn A. Harris, Damien Mack, Gema Méndez-Cervantes, Denise M. O’Sullivan, Vicky Pang, Zahra Sadouki, Priya Solanki, Jim F. Huggett, Timothy D. McHugh, Emmanuel Q. Wey
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Colonization and subsequent health care-associated infection (HCAI) with Acinetobacter baumannii are a concern for vulnerable patient groups within the hospital setting. Outbreaks involving multidrug-resistant strains are associated with inc
Externí odkaz:
https://doaj.org/article/91c090f3182c483d810e3595b6b29a35
Autor:
Catherine Berry, Philipp du Cros, Katherine Fielding, Suzanne Gajewski, Emil Kazounis, Timothy D. McHugh, Corinne Merle, Ilaria Motta, David A. J. Moore, Bern-Thomas Nyang’wa
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Background Globally rifampicin-resistant tuberculosis disease affects around 460,000 people each year. Currently recommended regimens are 9–24 months duration, have poor efficacy and carry significant toxicity. A shorter, less toxic and mo
Externí odkaz:
https://doaj.org/article/18cf0f1b88e446ff9f4a31b475111440
Autor:
Muhammad Hayat Haider, Timothy D. McHugh, Kerry Roulston, Liã Bárbara Arruda, Zahra Sadouki, Saba Riaz
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 21, Iss 1, Pp 1-8 (2022)
Abstract Background and objectives Burn patients are highly susceptible to invasion by multidrug-resistant Gram-negative bacteria (MDR-GNB) through post-burn damage. The prevalence of MDR-GNB isolated from burns patients has increased dramatically in
Externí odkaz:
https://doaj.org/article/89dce279c262485cad5c321685a9a8ba
Autor:
Alfonso J. Rodriguez-Morales, Darwin A. León-Figueroa, Luccio Romaní, Timothy D. McHugh, Hakan Leblebicioglu
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 21, Iss 1, Pp 1-5 (2022)
Externí odkaz:
https://doaj.org/article/3678c1adfd894cc3a0c01fecab3a96c4