Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Timothy D. Collins"'
Publikováno v:
Alcoholism: Clinical and Experimental Research. 16:757-763
Studies in folate-deficient alcoholics suggest that ethanol interferes with the recovery of folate status and the hematopoietic response to folate. Previous animal studies have suggested diverse effects of ethanol on intestinal absorption, hepatic me
Publikováno v:
The Journal of Nutritional Biochemistry. 3:182-187
Ethanol has been shown to be a teratogen in humans and experimental animals; however, the mechanism of its actions is not known. Because ethanol interferes with the metabolism of folate coenzymes that participate in various biosynthetic pathways of n
Publikováno v:
The Journal of nutrition. 122(4)
To study the tissue-specificity of folate deficiency, male Sprague-Dawley rats were fed folate-replete or folate-deficient diets with and without sulfonamide for 16 wk, and then injected with [3H]folic acid (1.5 nmol/kg). Rats were killed after 24 h,
Publikováno v:
Zurich, Switzerland, September 3–8, 1989
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46eb05358f6a5b94dc311d574a324c73
https://doi.org/10.1515/9783110889000-242
https://doi.org/10.1515/9783110889000-242
Publikováno v:
Journal of Toxicology: Clinical Toxicology. 26:451-466
4-Methylpyrazole (4-MP), a potent competitive inhibitor of alcohol dehydrogenase activity, is being studied as a therapeutic agent for methanol and ethylene glycol poisoning. In order to evaluate the distribution of 4-MP using doses in the potentiall
Publikováno v:
Pharmacology Biochemistry and Behavior. 18:257-262
Chronic ethanol use can lead to folic acid deficiency in humans. In rats, acute doses of ethanol produce a marked increase in urinary folate excretion, which precedes a decrease in plasma folate levels. To assess the role of ethanol and its metabolis
Publikováno v:
Biochemical Pharmacology. 32:2549-2555
Chronic ethanol use can lead to folic acid deficiency in humans. In rats, acute doses of ethanol produce a marked increase in the urinary excretion of folate which is followed by a decrease in plasma folate levels. To assess the respective roles of e
Publikováno v:
Alcohol. 2:473-477
Previous studies with rats showed that acute treatment with ethanol (4 g/kg) produce a marked increase in urinary folate levels, followed by a decrease in plasma folate levels. Analogous studies with human volunteer subjects using a lower dose of eth
Publikováno v:
Journal of Toxicology: Clinical Toxicology. 22:133-148
4-Methylpyrazole (4-MP), a potent competitive inhibitor of alcohol dehydrogenase activity, has potential usefulness as a treatment means for methanol and ethylene glycol poisoning as well as severe disulfiram-ethanol interactions. Further study of th
Publikováno v:
The Journal of nutrition. 116(7)
The folate deficiency that is produced by chronic alcohol ingestion results from poor dietary intake and from effects of ethanol on folate metabolism and absorption. Previous studies in fasted rats showed that singular treatment with ethanol produces