Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Timothy D Butters"'
Autor:
Erick A Perez Alday, Michael A Colman, Philip Langley, Timothy D Butters, Jonathan Higham, Antony J Workman, Jules C Hancox, Henggui Zhang
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 1, p e1004026 (2015)
Rapid atrial arrhythmias such as atrial fibrillation (AF) predispose to ventricular arrhythmias, sudden cardiac death and stroke. Identifying the origin of atrial ectopic activity from the electrocardiogram (ECG) can help to diagnose the early onset
Externí odkaz:
https://doaj.org/article/4eac07f94f964133a16c8d1881f28eb0
Autor:
Timothy D Butters, Simon J Castro, Tristan Lowe, Yanmin Zhang, Ming Lei, Philip J Withers, Henggui Zhang
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105552 (2014)
X-ray computed tomography (XCT) has been shown to be an effective imaging technique for a variety of materials. Due to the relatively low differential attenuation of X-rays in biological tissue, a high density contrast agent is often required to obta
Externí odkaz:
https://doaj.org/article/aad3db551e7e4f0cbae5806244c5aa07
Autor:
Jichao Zhao, Gregory B. Sands, Ian J. LeGrice, Henggui Zhang, Bruce H. Smaill, Timothy D. Butters, Andrew J. Pullan
Publikováno v:
Circulation: Arrhythmia and Electrophysiology. 5:361-370
Background— Computer models that capture key features of the heterogeneous myofiber architecture of right and left atria and interatrial septum provide a means of investigating the mechanisms responsible for atrial arrhythmia. The data necessary to
Publikováno v:
CASE
Alarm systems are vital for the safe operation of almost all large-scale industrial and technical installations, such as chemical plants or power stations. The optimization of alarm systems has great potential to improve the safety of these installat
Publikováno v:
Asset Management Conference 2015.
Large-scale industrial plants require physical sensors to continuously measure quantities such as temperatures or pressures. A large number of sensors is required to accurately describe the operating state of the plant, which unfortunately makes it v
Publikováno v:
Asset Management Conference 2014.
The effective performance of an alarm system is a key aspect of asset management for any industrial installation. However, it is not uncommon for alarm systems to be poorly configured, leading to large amounts of alarm noise and a potentially dangero
Autor:
Ian J. LeGrice, Gregory B. Sands, Bruce H. Smaill, Jichao Zhao, Henggui Zhang, Timothy D. Butters
Publikováno v:
IEEE transactions on medical imaging. 32(1)
Computer models provide a powerful platform for investigating mechanisms that underlie atrial rhythm disturbances. We have used novel techniques to build a structurally-detailed, image-based model of 3-D atrial anatomy. A volume image of the atria fr
Publikováno v:
Interface focus. 3(2)
Sheep are often used as animal models for experimental studies into the underlying mechanisms of cardiac arrhythmias. Previous studies have shown that biophysically detailed computer models of the heart provide a powerful alternative to experimental
Autor:
Ismail Adeniran, Arun V. Holden, Jules C. Hancox, Jonathan Higham, Timothy D. Butters, Henggui Zhang, Mark R. Boyett
Publikováno v:
Frontiers in Physiology, Vol 3 (2012)
Frontiers in Physiology
Frontiers in Physiology
β-adrenergic stimulation increases the heart rate by accelerating the electrical activity of the pacemaker of the heart, the sinoatrial node (SAN). Ionic mechanisms underlying the actions of β-adrenergic stimulation are not yet fully understood. Is
Publikováno v:
EMBC
Scopus-Elsevier
Scopus-Elsevier
Heterogeneity in the electrical action potential (AP) properties can provide a substrate for atrial arrhythmias, especially at rapid pacing rates. In order to quantify such substrates, we develop a family of detailed AP models for canine atrial cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4e6de6ab9b9252373c4287ce740886a
https://europepmc.org/articles/PMC3403810/
https://europepmc.org/articles/PMC3403810/