Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Timothy D, Wiltshire"'
Autor:
Jennifer Cable, Erica Ollmann Saphire, Adrian C. Hayday, Timothy D. Wiltshire, Jarrod J. Mousa, David P. Humphreys, Esther C. W. Breij, Pierre Bruhns, Matteo Broketa, Genta Furuya, Blake M. Hauser, Matthieu Mahévas, Andrea Carfi, Tineke Cantaert, Peter D. Kwong, Prabhanshu Tripathi, Jonathan H. Davis, Neil Brewis, Bruce A. Keyt, Felix L. Fennemann, Vincent Dussupt, Arvind Sivasubramanian, Philip M. Kim, Reda Rawi, Eve Richardson, Daniel Leventhal, Rachael M. Wolters, Cecile A. W. Geuijen, Matthew A. Sleeman, Niccolo Pengo, Francesca Rose Donnellan
Publikováno v:
Annals of the New York Academy of Sciences. 1519:153-166
Therapeutic antibodies have broad indications across diverse disease states, such as oncology, autoimmune diseases, and infectious diseases. New research continues to identify antibodies with therapeutic potential as well as methods to improve upon e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351a2f61d632111c45e1bd85b269f42a
https://doi.org/10.1111/nyas.14915
https://doi.org/10.1111/nyas.14915
Autor:
George Vasmatzis, Fergus J. Couch, Robert R. McWilliams, Mark J. Truty, Benjamin R. Kipp, Timothy D. Wiltshire, Gloria M. Petersen, Subbaya Subramanian, Farhad Kosari, Faye R. Harris, Fariborz Rakhshan Rohakhtar, Joema Felipe Lima, Travis Drucker, James B. Smadbeck, Sarah H. Johnson, Geoffrey C. Halling, Steven N. Hart, Stephen J. Murphy
Combined Mate Pair and Whole Exome Sequencing data for all 24 tumors described in this study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeccd6d0c49bfedaac49dad1cf30cad4
https://doi.org/10.1158/0008-5472.22409315.v1
https://doi.org/10.1158/0008-5472.22409315.v1
Autor:
George Vasmatzis, Fergus J. Couch, Robert R. McWilliams, Mark J. Truty, Benjamin R. Kipp, Timothy D. Wiltshire, Gloria M. Petersen, Subbaya Subramanian, Farhad Kosari, Faye R. Harris, Fariborz Rakhshan Rohakhtar, Joema Felipe Lima, Travis Drucker, James B. Smadbeck, Sarah H. Johnson, Geoffrey C. Halling, Steven N. Hart, Stephen J. Murphy
Many somatic mutations have been detected in pancreatic ductal adenocarcinoma (PDAC), leading to the identification of some key drivers of disease progression, but the involvement of large genomic rearrangements has often been overlooked. In this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26a8104e04383b39cba08f26147ac942
https://doi.org/10.1158/0008-5472.c.6507752
https://doi.org/10.1158/0008-5472.c.6507752
Autor:
George Vasmatzis, Fergus J. Couch, Robert R. McWilliams, Mark J. Truty, Benjamin R. Kipp, Timothy D. Wiltshire, Gloria M. Petersen, Subbaya Subramanian, Farhad Kosari, Faye R. Harris, Fariborz Rakhshan Rohakhtar, Joema Felipe Lima, Travis Drucker, James B. Smadbeck, Sarah H. Johnson, Geoffrey C. Halling, Steven N. Hart, Stephen J. Murphy
Comparison of current data with published data sets of PDAC.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b1d432cc8861cf482aa979debef8ec4
https://doi.org/10.1158/0008-5472.22409312
https://doi.org/10.1158/0008-5472.22409312
Autor:
George Vasmatzis, Fergus J. Couch, Robert R. McWilliams, Mark J. Truty, Benjamin R. Kipp, Timothy D. Wiltshire, Gloria M. Petersen, Subbaya Subramanian, Farhad Kosari, Faye R. Harris, Fariborz Rakhshan Rohakhtar, Joema Felipe Lima, Travis Drucker, James B. Smadbeck, Sarah H. Johnson, Geoffrey C. Halling, Steven N. Hart, Stephen J. Murphy
Supplemental figure legends to accompany supplemental data file
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a345c875baf06dbef523006f205a7943
https://doi.org/10.1158/0008-5472.22409321
https://doi.org/10.1158/0008-5472.22409321
Autor:
George Vasmatzis, Fergus J. Couch, Robert R. McWilliams, Mark J. Truty, Benjamin R. Kipp, Timothy D. Wiltshire, Gloria M. Petersen, Subbaya Subramanian, Farhad Kosari, Faye R. Harris, Fariborz Rakhshan Rohakhtar, Joema Felipe Lima, Travis Drucker, James B. Smadbeck, Sarah H. Johnson, Geoffrey C. Halling, Steven N. Hart, Stephen J. Murphy
Supplemental Table 1 and Figures 1-5 combined in single PDF file. Supplemental Table 1: Mate Pair sequencing data statistics. Supplemental Figure 1: KRAS Mutations in PDAC tumors. Supplemental Figure 2: Frequency copy number plots at the SMAD4 locus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6f7c77c406c2f457455c6be2711c548
https://doi.org/10.1158/0008-5472.22409318.v1
https://doi.org/10.1158/0008-5472.22409318.v1
Autor:
Darcie J. Radel, Allan B. Dietz, Michael C. Deeds, Clint S. Schmidt, Eapen K. Jacob, Julia M. Thebiay, Linda L. Pelleymounter, Timothy D. Wiltshire, Alexander M. Bornschlegl, James R. Stubbs, Dennis A. Gastineau
Publikováno v:
Cytotherapy. 24:19-26
Background The rise of investigative and commercially available cell therapy products adds a new dynamic to academic medical centers; that is, the management of patient-specific cell products. The scope of cell therapy has rapidly expanded beyond in-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::211c79c077e2cf97e59ed6111a18a865
https://doi.org/10.1016/j.jcyt.2020.12.013
https://doi.org/10.1016/j.jcyt.2020.12.013
Autor:
Maggie, Li, Evan J, Beck, Oliver, Laeyendecker, Yolanda, Eby, Aaron Ar, Tobian, Patrizio, Caturegli, Camille, Wouters, Gregory R, Chiklis, William, Block, Robert, McKie, Michael, Joyner, Timothy D, Wiltshire, Allan B, Dietz, Thomas J, Gniadek, Arell, Shapiro, Anusha, Yarava, Karen, Lane, Daniel, Hanley, Evan M, Bloch, Shmuel, Shoham, Edward R, Cachay, Barry R, Meisenberg, Moises A, Huaman, Yuriko, Fukuta, Bela, Patel, Sonya L, Heath, Adam C, Levine, James H, Paxton, Shweta, Anjan, Jonathan M, Gerber, Kelly A, Gebo, Arturo, Casadevall, Andrew, Pekosz, David J, Sullivan
The ongoing evolution of SARS-Co-V2 variants to omicron severely limits available effective monoclonal antibody therapies. Effective drugs are also supply limited. Covid-19 convalescent plasma (CCP) qualified for high antibody levels effectively redu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6199d9acbccaa1d265935e09706859a2
https://doi.org/10.1101/2022.03.01.22271662
https://doi.org/10.1101/2022.03.01.22271662
Autor:
Maggie Li, Evan J. Beck, Oliver Laeyendecker, Yolanda Eby, Aaron A. R. Tobian, Patrizio Caturegli, Camille Wouters, Gregory R. Chiklis, William Block, Robert O. McKie, Michael J. Joyner, Timothy D. Wiltshire, Allan B. Dietz, Thomas J. Gniadek, Arell J. Shapiro, Anusha Yarava, Karen Lane, Daniel F. Hanley, Evan M. Bloch, Shmuel Shoham, Edward R. Cachay, Barry R. Meisenberg, Moises A. Huaman, Yuriko Fukuta, Bela Patel, Sonya L. Heath, Adam C. Levine, James H. Paxton, Shweta Anjan, Jonathan M. Gerber, Kelly A. Gebo, Arturo Casadevall, Andrew Pekosz, David J. Sullivan
Publikováno v:
Blood advances. 6(12)
The ongoing evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants severely limits available effective monoclonal antibody therapies. Effective drugs are also supply limited. COVID-19 convalescent plasma (CCP) qualified fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26bdc54a4450c93012320f8738fbb00
https://pubmed.ncbi.nlm.nih.gov/35262085
https://pubmed.ncbi.nlm.nih.gov/35262085
Autor:
Mandy Ducy, Jacques Simard, Bing Xia, Fergus J. Couch, Amélie Rodrigue, Chunling Hu, Thiago T. Gomes, Tzeh Keong Foo, Alvaro N.A. Monteiro, Timothy D. Wiltshire, Marcelo A. Carvalho, Jean-Yves Masson, Anil Belur Nagaraj, Kun Y. Lee
Publikováno v:
Genetics in Medicine
Purpose Inherited pathogenic variants in PALB2 are associated with increased risk of breast and pancreatic cancer. However, the functional and clinical relevance of many missense variants of uncertain significance (VUS) identified through clinical ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70b0e1811d3d56de39359285af91a3ef
https://doi.org/10.1038/s41436-019-0682-z
https://doi.org/10.1038/s41436-019-0682-z