Výsledky vyhledávání - "Timothy D, Folsom"

Akademický článek

A review of traditional and novel treatments for seizures in autism spectrum disorder: Findings from a systematic review and expert panel.

Autor: Richard Eugene Frye, Daniel eRossignol, Manuel F Casanova, Vicki eMartin, Gregory eBrown, Stephen M. Edelson, Robert eCoben, Jeffrey David Lewine, John C Slattery, Chrystal eLau, Paul eHardy, S Hossein eFatemi, Timothy D. Folsom, Derrick Fraser MacFabe, James eAdams

Publikováno v: Frontiers in Public Health, Vol 1 (2013)

Despite the fact that seizures are commonly associated with autism spectrum disorder (ASD), the effectiveness of treatments for seizures has not been well studied in individuals with ASD. This manuscript reviews both traditional and novel treatments

Externí odkaz: https://doaj.org/article/b215de36d8f241259032c60db7cd64e4

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Metabotropic glutamate receptor 5 tracer [18F]-FPEB displays increased binding potential in postcentral gyrus and cerebellum of male individuals with autism: a pilot PET study

Autor: George M. Realmuto, Suma Jacob, Timothy D. Folsom, José V. Pardo, Susanne S. Lee, James Robert Brašić, S. Hossein Fatemi, Hiroto Kuwabara, Dean F. Wong, Anil Mathur

Publikováno v: Cerebellum & Ataxias, Vol 5, Iss 1, Pp 1-8 (2018)

Background Autism is a neurodevelopmental disorder that is first manifested during early childhood. Postmortem experiments have identified significantly elevated expression of metabotropic glutamate receptor 5 (mGluR5) in cerebellar vermis and prefro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb5cd55467dd9a7372d92717cffb2350
http://link.springer.com/article/10.1186/s40673-018-0082-1

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The effects of prenatal H1N1 infection at E16 on FMRP, glutamate, GABA, and reelin signaling systems in developing murine cerebellum

Autor: Timothy D. Folsom, S. Hossein Fatemi, Stephanie B. Liesch, Paul Thuras, Rachel E. Kneeland, Mahtab K Yousefi

Publikováno v: Journal of Neuroscience Research. 95:1110-1122

Prenatal viral infection has been identified as a potential risk factor for the development of neurodevelopmental disorders such as schizophrenia and autism. Additionally, dysfunction in gamma-aminobutyric acid, Reelin, and fragile X mental retardati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0db3cdf0c2f0a0e109ecebcd4ecb5584
https://doi.org/10.1002/jnr.23949

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Quantitative proteomics of forebrain subcellular fractions in fragile X mental retardation 1 knockout mice following acute treatment with 2‐Methyl‐6‐(phenylethynyl)pyridine: Relevance to developmental study of schizophrenia

Autor: S. Hossein Fatemi, LeeAnn Higgins, Todd W. Markowski, Timothy D. Folsom, Timothy J. Griffin

Publikováno v: Synapse. 73

The fragile X mental retardation 1 knockout (Fmr1 KO) mouse replicates behavioral deficits associated with autism, fragile X syndrome, and schizophrenia. Less is known whether protein expression changes are consistent with findings in subjects with s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30e731a0ef8d03bfdbbd482628dd1888
https://doi.org/10.1002/syn.22069

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Protein expression of targets of the FMRP regulon is altered in brains of subjects with schizophrenia and mood disorders

Autor: Paul Thuras, S. Hossein Fatemi, Timothy D. Folsom

Publikováno v: Schizophrenia Research. 165:201-211

Fragile X mental retardation protein (FMRP) is an RNA binding protein with 842 target mRNAs in mammalian brain. Silencing of the fragile X mental retardation 1 (FMR1) gene leads to loss of expression of FMRP and upregulated metabotropic glutamate rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e33b3a1dc3211fa658fe5c69e2b9c73
https://doi.org/10.1016/j.schres.2015.04.012

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Metabotropic glutamate receptor 5 tracer [

Autor: S Hossein, Fatemi, Dean F, Wong, James R, Brašić, Hiroto, Kuwabara, Anil, Mathur, Timothy D, Folsom, Suma, Jacob, George M, Realmuto, José V, Pardo, Susanne, Lee

Publikováno v: Cerebellum & Ataxias

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7d2278f4e389973d8674b35dc111b098
https://pubmed.ncbi.nlm.nih.gov/29449954

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Altered subcellular localization of fragile X mental retardation signaling partners and targets in superior frontal cortex of individuals with schizophrenia

Autor: Timothy D. Folsom, Paul Thuras, S. Hossein Fatemi

Publikováno v: Neuroreport. 28(16)

Schizophrenia is a severe, debilitating, neurodevelopmental disorder that affects 1% of the world's population. Recent findings from our laboratory have identified reduced levels of fragile X mental retardation protein (FMRP) and several downstream F

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ede57fbbcf9e0c64e5389529cc2aae9
https://pubmed.ncbi.nlm.nih.gov/28902714

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GABA

Autor: S Hossein, Fatemi, Timothy D, Folsom, Paul D, Thuras

Publikováno v: Synapse (New York, N.Y.). 71(7)

Schizophrenia and bipolar disorder are complex psychiatric disorders that affect millions of people worldwide. Evidence from gene association and postmortem studies has identified abnormalities of the gamma-aminobutyric acid (GABA) signaling system i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5f29e30c3d2bc5942668a7e406e09541
https://pubmed.ncbi.nlm.nih.gov/28316115

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