Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Timothy Connelly"'
Autor:
Angela Holder, Rachel Garty, Charlotte Elder, Paula Mesnard, Celine Laquerbe, Marie-Christine Bartens, Mazdak Salavati, Muhammad Zubair Shabbir, Thomas Tzelos, Timothy Connelly, Bernardo Villarreal-Ramos, Dirk Werling
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Bovine tuberculosis (bTB), caused by Mycobacterium bovis, is a chronic zoonotic disease where host genetics is thought to contribute to susceptibility or resistance. One of the genes implicated is the SLC11A1 gene, that encodes for the natural resist
Externí odkaz:
https://doaj.org/article/0593887074e44f9e90253a66646a31ea
Autor:
Liquan Huang, Jennifer L. Pluznick, Xuanmao Chen, Huikai Tian, Kai Zhao, Timothy Connelly, Wenbin Yin, Limei Ma, Jue Wang, Jiwei He, Jianbo Jiang, Minghong Ma, Daniel R. Storm, Rosemary C. Challis, C. Ron Yu
Publikováno v:
Current Biology. 25:2503-2512
SummaryIn many sensory organs, specialized receptors are strategically arranged to enhance detection sensitivity and acuity. It is unclear whether the olfactory system utilizes a similar organizational scheme to facilitate odor detection. Curiously,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7501a38e23eac468310615bde4d69f8f
https://doi.org/10.1016/j.cub.2015.07.065
https://doi.org/10.1016/j.cub.2015.07.065
Publikováno v:
Neuroscience Letters. 511:12-17
The calcium control hypothesis posits that postsynaptic calcium increases are required to trigger synaptic plasticity, with large increases inducing LTP and small increases inducing LTD. In CA1 of the hippocampus, however, LTD induced by chemical act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230614271bbc63b114aaabb9ec098292
https://doi.org/10.1016/j.neulet.2012.01.003
https://doi.org/10.1016/j.neulet.2012.01.003
Autor:
Jian Zhang, Guo-Qiang Chen, Xu-Fang Duan, Qiuyi Chi, Shao-Zhong Zhang, Hiroaki Matsunami, Eric Block, Xubo Su, Timothy Connelly, Hanyi Zhuang, Minghong Ma, Zhen Li, Lifang Wu, Zhimin Huang, Siji Thomas, Yi Pan
Publikováno v:
Proceedings of the National Academy of Sciences. 109:3492-3497
Odorant receptors (ORs) in olfactory sensory neurons (OSNs) mediate detection of volatile odorants. Divalent sulfur compounds, such as thiols and thioethers, are extremely potent odorants. We identify a mouse OR, MOR244-3, robustly responding to (met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfcfb5cdcc04e3cb4c1de879ece29d99
https://doi.org/10.1073/pnas.1111297109
https://doi.org/10.1073/pnas.1111297109
Publikováno v:
European Journal of Pharmacology. 667:160-168
Metabotropic glutamate receptor mediated long-term depression (mGlu receptor LTD) is evoked in hippocampal area CA1 chemically by the agonist 3,5-Dihydroxyphenylglycine (DHPG, agonist LTD) and synaptically by paired-pulse low frequency stimulation (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb161e55c2dd868d0b66c64975c46e5
https://doi.org/10.1016/j.ejphar.2011.04.063
https://doi.org/10.1016/j.ejphar.2011.04.063
Autor:
Xavier Grosmaitre, Zhenshan Wang, Yiqun Yu, Xin Qiao, Agnès Savigner, Minghong Ma, Timothy Connelly, Daniel R. Storm, Lindsey Ciali Santarelli, Jue Wang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2015, 112 (2), pp.590-595. ⟨10.1073/pnas.1418515112⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2015, 112 (2), pp.590-595. 〈10.1073/pnas.1418515112〉
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2015, 112 (2), pp.590-595. ⟨10.1073/pnas.1418515112⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2015, 112 (2), pp.590-595. 〈10.1073/pnas.1418515112〉
Mechanosensitive cells are essential for organisms to sense the external and internal environments, and a variety of molecules have been implicated as mechanical sensors. Here we report that odorant receptors (ORs), a large family of G protein-couple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::425a33f840b6b51ea997e3a6a7a2db54
https://hal.archives-ouvertes.fr/hal-01187877
https://hal.archives-ouvertes.fr/hal-01187877
Publikováno v:
Journal of neurophysiology. 110(1)
Sensory systems need to tease out stimulation-evoked activity against a noisy background. In the olfactory system, the odor response profile of an olfactory sensory neuron (OSN) is dependent on the type of odorant receptor it expresses. OSNs also exh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fdfc21cfcecd561b9bf84f4e203bf39
https://pubmed.ncbi.nlm.nih.gov/23596334
https://pubmed.ncbi.nlm.nih.gov/23596334
Autor:
Lee E. Goldstein, Srikant Sarangi, Andrew Fraine, Juliet A. Moncaster, Olga Minaeva, Timothy Connelly, Mark W. Wojnarowicz, Noel Casey
Publikováno v:
Alzheimer's & Dementia. 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46cb53b6656760150866b7e70c66000c
https://doi.org/10.1016/j.jalz.2011.05.1114
https://doi.org/10.1016/j.jalz.2011.05.1114
Autor:
Juliet A. Moncaster, Olga Minaeva, Noel Casey, Srikant Sarangi, Lee E. Goldstein, Mark W. Wojnarowicz, Timothy Connelly
Publikováno v:
Alzheimer's & Dementia. 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3c3a4e530b09155da45c2a17028d2ec
https://doi.org/10.1016/j.jalz.2011.05.1113
https://doi.org/10.1016/j.jalz.2011.05.1113