Výsledky vyhledávání - "Timothy C. Granade"

A mAb for the detection of the antiretroviral drug emtricitabine

Autor: Ae S. Youngpairoj, Thomas H. Vanderford, Matthew S. Reed, Timothy C. Granade, Chou-Pong Pau, Jan Pohl, William M. Switzer, Walid Heneine

Publikováno v: AIDS (London, England). 36(13)

Antibody-based testing for emtricitabine (FTC), a critical component of pre-exposure prophylaxis and antiretroviral therapy, would provide low-cost detection for clinical monitoring to improve adherence. We developed a mAb (5D2) to FTC and demonstrat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baaecf7cc71a62d2df4c71f96aefb83c
https://pubmed.ncbi.nlm.nih.gov/36111696

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Akademický článek

Dual Simian Foamy Virus/Human Immunodeficiency Virus Type 1 Infections in Persons from Côte d'Ivoire.

Autor: William M Switzer, Shaohua Tang, HaoQiang Zheng, Anupama Shankar, Patrick S Sprinkle, Vickie Sullivan, Timothy C Granade, Walid Heneine

Publikováno v: PLoS ONE, Vol 11, Iss 6, p e0157709 (2016)

Zoonotic transmission of simian retroviruses in West-Central Africa occurring in primate hunters has resulted in pandemic spread of human immunodeficiency viruses (HIVs) and human T-lymphotropic viruses (HTLVs). While simian foamy virus (SFV) and sim

Externí odkaz: https://doaj.org/article/51505d8d9b5245a6a12c73e4b617960c

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Development and optimization of thermal contrast amplification lateral flow immunoassays for ultrasensitive HIV p24 protein detection

Autor: Jeffrey A. Johnson, John C. Bischof, Li Zhan, Xierong Wei, Yilin Liu, Vickie Sullivan, Ae S. Youngpairoj, Timothy C. Granade

Publikováno v: Microsystems & Nanoengineering, Vol 6, Iss 1, Pp 1-11 (2020)

Detection of human immunodeficiency virus (HIV) p24 protein at a single pg/ml concentration in point-of-care (POC) settings is important because it can facilitate acute HIV infection diagnosis with a detection sensitivity approaching that of laborato

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8073a20ece78463650c70763145adf2b
https://doi.org/10.1038/s41378-020-0168-9

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Trends in HIV-2 Diagnoses and Use of the HIV-1/HIV-2 Differentiation Test - United States, 2010-2017

Autor: John T. Brooks, William M. Switzer, Laura G. Wesolowski, Kevin P. Delaney, S. Michele Owen, Xueyuan Dong, Timothy C. Granade, Anne Harwood Peruski, Pollyanna R Chavez, M. Patricia Joyce, Vickie Sullivan

Publikováno v: Morbidity and Mortality Weekly Report

Since 2014, the recommended laboratory testing algorithm for diagnosing human immunodeficiency virus (HIV) infection has included a supplemental HIV-1/HIV-2 differentiation test to confirm infection type on the basis of the presence of type-specific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42b04df02b28a876245f6b6050f6ebfa
https://pubmed.ncbi.nlm.nih.gov/31971928

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A Strategy for PrEP Clinicians to Manage Ambiguous HIV Test Results During Follow-up Visits

Autor: Kevin P. Delaney, Dawn K. Smith, Philip J. Peters, John T. Brooks, Timothy C. Granade, Luke Shouse, Silvina Masciotra, William M. Switzer

Publikováno v: Open Forum Infectious Diseases

Prompt determination of HIV infection status is critical during follow-up visits for patients taking pre-exposure prophylaxis (PrEP) medication. Those who are uninfected can then continue safely taking PrEP, and those few who have acquired HIV infect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02b5c3ed9b5438d1b55f5ff5d9a88381
https://doi.org/10.1093/ofid/ofy180

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Characterization of real-time microarrays for simultaneous detection of HIV-1, HIV-2, and hepatitis viruses

Autor: Ae S. Youngpairoj, Kelly A. Curtis, Timothy C. Granade, Silvina Masciotra, S. Michele Owen, Susan K. Wells, Saleem Kamili, Maja Kodani

Publikováno v: Journal of virological methods. 259

Real-time PCR assays for nucleic acid testing (NAT) of hepatitis viruses A–E and for HIV-1 and HIV-2 have been developed; however, a multiplex assay that can simultaneously detect all of these agents is not yet available. Standardized TaqMan assays

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9366471aa9bc1559fe737da40d581cf
https://pubmed.ncbi.nlm.nih.gov/29874550

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Use of rapid HIV assays as supplemental tests in specimens with repeatedly reactive screening immunoassay results not confirmed by HIV-1 Western blot

Autor: Kevin P. Delaney, William A. Meyer, Pollyanna R Chavez, Amy J. Blatt, Berry Bennett, Laura G. Wesolowski, Timothy C. Granade, Michele Owen

Publikováno v: Journal of Clinical Virology. 58:240-244

An alternate HIV testing algorithm has been proposed which includes a fourth-generation immunoassay followed by an HIV-1/HIV-2 antibody differentiation supplemental test for reactive specimens and a nucleic acid test (NAT) for specimens with discorda

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff19878a2225f34be126e5c8d33a9e51
https://doi.org/10.1016/j.jcv.2013.06.019

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Development of a Novel Rapid HIV Test for Simultaneous Detection of Recent or Long-Term HIV Type 1 Infection Using a Single Testing Device

Autor: Timothy C. Granade, Shon Nguyen, Debra S Kuehl, Bharat Parekh

Publikováno v: AIDS Research and Human Retroviruses. 29:61-67

Laboratory assays for the detection of recent HIV infection for HIV incidence surveillance are essential to HIV prevention efforts worldwide because they can identify populations with a high incidence and allow targeting of resources and monitoring o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1943ee614926811b1cc5fa69a679e490
https://doi.org/10.1089/aid.2012.0121

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1970s and 'Patient 0' HIV-1 genomes illuminate early HIV/AIDS history in North America

Autor: Dirk E. Teuwen, Michael Worobey, Walid Heneine, Richard A. McKay, Philippe Lemey, Marc A. Suchard, Beryl A. Koblin, Timothy C. Granade, Thomas D. Watts, Harold W. Jaffe

Publikováno v: Nature, vol 539, iss 7627

The emergence of HIV-1 group M subtype B in North American men who have sex with men was a key turning point in the HIV/AIDS pandemic. Phylogenetic studies have suggested cryptic subtype B circulation in the United States (US) throughout the 1970s an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::515101107b5f7ced012d1bf7a968c317

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