Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Timothy C. Barden"'
Autor:
Ali R. Banijamali, Andrew E. Carvalho, James D. Wakefield, Peter Germano, Timothy C. Barden, Jenny V. Tobin, Daniel P. Zimmer, Jaime L. Masferrer, Albert T. Profy, Mark G. Currie, G. Todd Milne
Publikováno v:
Pharmacology Research & Perspectives, Vol 8, Iss 2, Pp n/a-n/a (2020)
Abstract The pharmacokinetics (PK), metabolism, excretion, mass balance, and tissue distribution of [14C]praliciguat were evaluated following oral administration of a 3‐mg/kg dose in Sprague‐Dawley rats and in a quantitative whole‐body autoradi
Externí odkaz:
https://doaj.org/article/644e106f3d284338801984e64cb31af8
Autor:
Benjamin Pelcman, Gordon W. Gribble, Michael S. Sinha, Wendy M. Habeski, Erin T. Pelkey, Judy A. Obaza-Nutaitis, Timothy C. Barden, Tara L. S. Kishbaugh, Jun Jiang, Louis Chang, Brett D. Allison, Karen S. Harpp, William R. Sponholtz, Hernando A. Trujillo, Meredeth A. McGowan, Ryan W. Chau, Saulnier Mark G, Nikolai V. Moskalev, Samuel C. Conway, Mukund P. Sibi, Yanbing Liu, Deborah A. Davis, Frank L. Switzer, Sujata Roy, Sarah D. Garaas, Richard A. Silva, Matthew R. Reese, Daniel J. Keavy
Publikováno v:
Current Organic Chemistry. 9:1493-1519
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7434125a111b53f8cf1b1bd619b9312d
https://doi.org/10.2174/138527205774370487
https://doi.org/10.2174/138527205774370487
Publikováno v:
Tetrahedron Letters. 40:7615-7619
2-Nitro-1-(phenylsulfonyl)indole ( 1 ) undergoes nucleophilic addition reactions with the enolates of diethyl malonate and cyclohexanone, lithium dimethylcuprate, and indole anion to afford the corresponding 3-substituted-2-nitroindoles ( 4–6, 8, 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0eeaeb811899ef7dc2d32e2c24ddf0f6
https://doi.org/10.1016/s0040-4039(99)01557-9
https://doi.org/10.1016/s0040-4039(99)01557-9
Autor:
Deborah A. Davis, Mukund P. Sibi, Saulnier Mark G, Erik R. Olson, Gordon W. Gribble, Benjamin Pelcman, Daniel J. Keavy, Joseph J. BelBruno, Timothy C. Barden
Publikováno v:
ChemInform. 24
Seven examples of the novel 4H-furo[3,4-b]indole ring system (3-9)-a stable, synthetic analogue of indole-2,3-quinodimethane have been synthesized in 6-8 steps from simple indoles in overall yiels of 21-28%. These 4H-furo[3,4-b]indoles undergo Diels-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::586db56bb2dbae61b01cff9785b0aa5f
https://doi.org/10.1002/chin.199309241
https://doi.org/10.1002/chin.199309241
Publikováno v:
ChemInform. 31
2-Nitro-1-(phenylsulfonyl)indole ( 1 ) undergoes nucleophilic addition reactions with the enolates of diethyl malonate and cyclohexanone, lithium dimethylcuprate, and indole anion to afford the corresponding 3-substituted-2-nitroindoles ( 4–6, 8, 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faac1169d6424708520735308a7294e6
https://doi.org/10.1002/chin.200003121
https://doi.org/10.1002/chin.200003121
Autor:
Timothy C. Barden
Publikováno v:
Topics in Heterocyclic Chemistry ISBN: 9783642157325
Indole-containing compounds are best known for their medicinal properties in the pharmaceutical industry. Although to a lesser degree, the indole motif none-the-less appears in many significant products across the entire chemical industry. This chapt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6b4a86334d34c7931eb5c1ebd8745e4
https://doi.org/10.1007/7081_2010_48
https://doi.org/10.1007/7081_2010_48
Autor:
Benjamin Pelcman, Mukund P. Sibi, Timothy C. Barden, Gordon W. Gribble, Joseph J. BelBruno, Erik R. Olson, Saulnier Mark G, Deborah A. Davis, Daniel J. Keavy
Publikováno v:
The Journal of Organic Chemistry. 57:5878-5891
Seven examples of the novel 4H-furo[3,4-b]indole ring system (3-9)-a stable, synthetic analogue of indole-2,3-quinodimethane have been synthesized in 6-8 steps from simple indoles in overall yiels of 21-28%. These 4H-furo[3,4-b]indoles undergo Diels-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50e48299956164ee836dc63efc3bc76e
https://doi.org/10.1021/jo00048a021
https://doi.org/10.1021/jo00048a021
Autor:
Timothy C. Barden, Karen S. Harpp, Jay H. Brown, B. H. Hirth, J. N. Dalbis, C. H. Bushweller, Gordon W. Gribble
Publikováno v:
The Journal of Organic Chemistry. 63:3775-3777
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b385b6a7bcef524d4f5d636f336ebfec
https://doi.org/10.1021/jo972305a
https://doi.org/10.1021/jo972305a
Autor:
Timothy C. Barden, John E. Baldwin
Publikováno v:
Journal of the American Chemical Society. 106:5312-5319
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8e848fa429b6386cf9ca9f38b46931f
https://doi.org/10.1021/ja00330a046
https://doi.org/10.1021/ja00330a046
Autor:
John E. Baldwin, Timothy C. Barden
Publikováno v:
Journal of the American Chemical Society. 106:6364-6367
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e0a02fa8ed84046c34c81bb01285e14
https://doi.org/10.1021/ja00333a042
https://doi.org/10.1021/ja00333a042