Výsledky vyhledávání - "Timothy C, Fisher"

Thermoreversible Reverse-Phase-Shift Foam for Treatment of Noncompressible Torso Hemorrhage, a Safety Trial in a Porcine Model

Autor: Ross I, Donaldson, Timothy C, Fisher, Todd L, Graham, Oliver J, Buchanan, John S, Cambridge, Jonathan K, Armstrong, Diane, Goldenberg, David A, Tanen, James D, Ross

Publikováno v: Military Medicine.

Introduction Noncompressible torso hemorrhage is the leading cause of exsanguination on the battlefield. A self-expanding, intraperitoneal deployed, thermoreversible foam has been developed that can be easily administered by a medic in austere settin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734dd04830bd180b53757bfe130a4837
https://doi.org/10.1093/milmed/usac206

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Thermoreversible Reverse-Phase-Shift Foam for Treatment of Noncompressible Torso Hemorrhage

Autor: Eric Zimmermann, John Cambridge, Todd L. Graham, Timothy C. Fisher, Oliver J. Buchanan, Jonathan K. Armstrong, James D. Ross, Ross I. Donaldson

Publikováno v: Journal of Surgical Research. 259:175-181

Background Noncompressible torso hemorrhage (NCTH) is a leading cause of traumatic exsanguination, requiring emergent damage control surgery performed by a highly trained surgeon in a sterile operating environment. A self-expanding, intraabdominally

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89998e134118e51677205a321521443e
https://doi.org/10.1016/j.jss.2020.11.039

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Efficacy of past, present, and future fluid strategies in an improved large animal model of non-compressible intra-abdominal hemorrhage

Autor: Jonathan K Armstrong, Ross I. Donaldson, Oliver J. Buchanan, James D. Ross, John Cambridge, Todd L Graham, Timothy C Fisher

Publikováno v: The journal of trauma and acute care surgery. 91(2S Suppl 2)

Background Noncompressible hemorrhage is a leading cause of potentially survivable combat death, with the vast majority of such deaths occurring in the out-of-hospital environment. While large animal models of this process are important for device an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb983d628391e3de86803f9a6c20dc5
https://pubmed.ncbi.nlm.nih.gov/34324472

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Sickle cell disease: Selected aspects of pathophysiology

Autor: Jean Claude Barthélémy, Philippe Connes, Herbert J. Meiselman, Michael C.K. Khoo, Tamas Alexy, Timothy C. Fisher, Suvimol Sangkatumvong, Thomas D. Coates, Julien Tripette, Eszter Pais

Publikováno v: Clinical Hemorheology and Microcirculation. 44:155-166

Sickle cell disease (SCD), a genetically-determined pathology due to an amino acid substitution (i.e., valine for glutamic acid) on the beta-chain of hemoglobin, is characterized by abnormal blood rheology and periods of painful vascular occlusive cr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3df278106f9a025935e7feed9075c6ae
https://doi.org/10.3233/ch-2010-1270

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The Effects of a Soluble Polymer and Bone Wax on Sternal Healing in an Animal Model

Autor: Tadeusz, Wellisz, Jonathan K, Armstrong, John, Cambridge, Yuehuei H, An, Xuejun, Wen, Qian, Kang, Christopher M, Hill, Timothy C, Fisher

Publikováno v: The Annals of Thoracic Surgery. 85:1776-1780

This study compares the effects of a soluble polymer hemostatic material and bone wax on sternal bone healing.Median sternotomies were performed on 20 New Zealand White rabbits, and sufficient polymer (Ostene; Ceremed Inc, Los Angeles CA) or bone wax

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b91b2e950987b27cd714a5a79e8fc7
https://doi.org/10.1016/j.athoracsur.2007.11.042

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Antibody against poly(ethylene glycol) adversely affects PEG-asparaginase therapy in acute lymphoblastic leukemia patients

Autor: Georg Hempel, Herbert J. Meiselman, Jonathan K. Armstrong, Linda S. Chan, Susanne Koling, Timothy C. Fisher, George Garratty

Publikováno v: Cancer. 110:103-111

BACKGROUND. Rapid clearance of poly(ethylene glycol)-asparaginase (PEGASNase) has been reported for up to one-third of patients treated for acute lymphoblastic leukemia (ALL), potentially rendering their treatment ineffective. A 25% occurrence of an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b3be64b8b694abaa701aa383ce19fd8
https://doi.org/10.1002/cncr.22739

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Ostene, a New Water-Soluble Bone Hemostasis Agent

Autor: Tadeusz Wellisz, John Cambridge, Jonathan K. Armstrong, Timothy C. Fisher

Publikováno v: Journal of Craniofacial Surgery. 17:420-425

Traditional formulations of bone wax are composed largely of beeswax and are well known to interfere with bone healing and cause inflammatory reactions. Ostene, a newly available bone hemostasis agent made of water-soluble alkylene oxide copolymers,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e572102529199ec8f79390a80ec4e8f
https://doi.org/10.1097/00001665-200605000-00006

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Abnormal blood rheology and chronic low grade inflammation: possible risk factors for accelerated atherosclerosis and coronary artery disease in Lewis negative subjects

Autor: Howard N. Hodis, Jun Wang, Rosalinda B. Wenby, Wendy J. Mack, Naoko Kono, Timothy C. Fisher, Eszter Pais, Herbert J. Meiselman, Oguz K. Baskurt, Tamas Alexy

Publikováno v: Atherosclerosis. 239(1)

To test the hypothesis that abnormal hemorheology and chronic low-grade inflammation are more prevalent in Lewis negative individuals, possibly contributing to premature atherosclerosis.We enrolled 223 healthy subjects (154 females, mean age: 64yrs).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a4e53a239af89ca3a2271a351eacf9
https://pubmed.ncbi.nlm.nih.gov/25626016

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A New, Pluronic-based, Bone Hemostatic Agent That Does Not Impair Osteogenesis

Autor: Michael Levy, Jonathan K. Armstrong, Herbert J. Meiselman, Timothy C. Fisher, Michael Wang, Gordon McComb

Publikováno v: Neurosurgery. 49:962-968

OBJECTIVE: Intraoperative bone hemostasis can be accomplished using surgical beeswax (bone wax). However, bone wax locally interferes with osteogenesis, and its use is avoided when bone fusion is critical. We describe the use of a Pluronic copolymer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027d56edf58d010bbeb051e621d45e7b
https://doi.org/10.1227/00006123-200110000-00031

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Polyethylene glycol–coated red blood cells fail to bind glycophorin A–specific antibodies and are impervious to invasion by the Plasmodium falciparum malaria parasite

Autor: Jonathan K. Armstrong, Herbert J. Meiselman, Timothy C. Fisher, Douglas P. Blackall

Publikováno v: Blood. 97:551-556

This study was designed to assess the binding of glycophorin A–specific antibodies to polyethylene glycol (PEG)-modified red blood cells (RBCs) and evaluate their resistance to invasion byPlasmodium falciparum malaria parasites. RBCs were conjugate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f96c5a0cebb4de5a366e1ad96394355f
https://doi.org/10.1182/blood.v97.2.551

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