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Publikováno v:
Journal of Biological Chemistry. 270:25651-25655
The compound 4-(fluoromethyl)phenyl phosphate (FMPP), recently shown to be a mechanism-based inhibitor of prostatic acid phosphatase (Myers, J. K., and Widlanski, T. S.(1993) Science 262, 1451-1453), was examined for its effect on calcineurin. This c
Publikováno v:
Nature. 376(6542)
The neuronal growth cone is thought to be the site of decision making in nerve growth and guidance. One likely mechanism of how the growth cone translates various extracellular cues into directed motility involves rises in intracellular calcium. A va
Autor:
Lynne D. Zydowsky, Timothy Born, Christopher T. Walsh, Frank Rusnak, Selene K. H. Swanson, Howard Y. Chang, Hyeongjin Cho
The Ca(2+)- and calmodulin-dependent protein phosphatase calcineurin is inhibited by the immunosuppressant drug cyclosporin A in the presence of cyclophilin A or B. Of the two isoforms, cyclophilin B is more potent by a factor of 2-5 when either the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25e7d1918bfb0590abceca80c8202d1a
https://europepmc.org/articles/PMC525566/
https://europepmc.org/articles/PMC525566/