Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Timothy Blewett"'
Autor:
Reid W. Merryman, Justin Rhoades, Kan Xiong, Robert A. Redd, Katherine Antel, Hyun Hwan An, Mikaela McDonough, Liliana Guerrero, Andela Crnjac, Sainetra Sridhar, Timothy Blewett, Ju Cheng, Parastoo B. Dahi, Yago Nieto, Robin M. Joyce, Yi‐Bin Chen, Alex F. Herrera, Philippe Armand, Mark Murakami, Viktor A. Adalsteinsson
Publikováno v:
HemaSphere, Vol 8, Iss 4, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/e0741558ee924929be7e37b4c914c7ba
Autor:
Jin H. Bae, Ruolin Liu, Eugenia Roberts, Erica Nguyen, Shervin Tabrizi, Justin Rhoades, Timothy Blewett, Kan Xiong, Gregory Gydush, Douglas Shea, Zhenyi An, Sahil Patel, Ju Cheng, Sainetra Sridhar, Mei Hong Liu, Emilie Lassen, Anne-Bine Skytte, Marta Grońska-Pęski, Jonathan E. Shoag, Gilad D. Evrony, Heather A. Parsons, Erica L. Mayer, G. Mike Makrigiorgos, Todd R. Golub, Viktor A. Adalsteinsson
Publikováno v:
Nature Genetics. 55:871-879
Detecting mutations from single DNA molecules is crucial in many fields but challenging. Next-generation sequencing (NGS) affords tremendous throughput but cannot directly sequence double-stranded DNA molecules (‘single duplexes’) to discern the
Autor:
Heather A. Parsons, Timothy Blewett, Xiangying Chu, Sainetra Sridhar, Katheryn Santos, Kan Xiong, Vandana Abramson, Ashka Patel, Ju Cheng, Adam M. Brufsky, Justin Rhoades, Jeremy Force, Ruolin Liu, Tiffany A. Traina, Lisa Carey, Mothaffar Rimawi, Ahmed Elkhanany, Vered Stearns, Jennifer M. Specht, Harold Burstein, Antonio C. Wolff, Eric Winer, Nabihah Tayob, Ian Krop, Todd Golub, Erica L. Mayer, Viktor Adalsteinsson
Publikováno v:
Cancer Research. 83:PD11-06
Background. Patients (pts) with early triple negative breast cancer (eTNBC) are at increased risk of breast cancer recurrence and death. Recent studies have focused on escalation of therapy, with current treatment standard of at least five drugs –
Autor:
Timothy Blewett, Adrian Hyde-Price
Whilst the views of leaders within the Church of England are frequently canvassed during periods of national crisis, little attention has been devoted to finding out whether there are Church perspectives on contemporary foreign policy issues. The Chu
Autor:
Heather A. Parsons, Timothy Blewett, Xiangying Chu, Sainetra Sridhar, Katheryn Santos, Kan Xiong, Vandana G. Abramson, Ashka Patel, Ju Cheng, Adam Brufsky, Justin Rhoades, Jeremy Force, Ruolin Liu, Tiffany A. Traina, Lisa A. Carey, Mothaffar F. Rimawi, Kathy D. Miller, Vered Stearns, Jennifer Specht, Carla Falkson, Harold J. Burstein, Antonio C. Wolff, Eric P. Winer, Nabihah Tayob, Ian E. Krop, G. Mike Makrigiorgos, Todd R. Golub, Erica L. Mayer, Viktor A. Adalsteinsson
PurposeTo examine circulating tumor DNA (ctDNA) and its association with residual cancer burden (RCB) using an ultrasensitive assay in patients with triple-negative breast cancer (TNBC) receiving neoadjuvant chemotherapy (NAT).Patients and MethodsWe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0efe38a97b91031b3386007c5702a943
https://doi.org/10.1101/2023.03.06.23286772
https://doi.org/10.1101/2023.03.06.23286772
Autor:
Shervin Tabrizi, Carmen Martin-Alonso, Kan Xiong, Timothy Blewett, Sainetra Sridhar, Zhenyi An, Sahil Patel, Sergio Rodriguez-Aponte, Christopher A. Naranjo, Shih-Ting Wang, Douglas Shea, Todd R. Golub, Sangeeta N. Bhatia, Viktor Adalsteinsson, J. Christopher Love
Publikováno v:
bioRxiv
Blood-based, or “liquid,” biopsies enable minimally invasive diagnostics but have limits on sensitivity due to scarce cell-free DNA (cfDNA). Improvements to sensitivity have primarily relied on enhancing sequencing technologyex vivo. Here, we sou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78f801620377ed2460cada89da0da0f1
https://doi.org/10.1101/2023.01.13.523947
https://doi.org/10.1101/2023.01.13.523947
Autor:
Carmen Martin-Alonso, Shervin Tabrizi, Kan Xiong, Timothy Blewett, Sahil Patel, Zhenyi An, Sainetra Sridhar, Ahmet Bekdemir, Douglas Shea, Ava P. Amini, Shih-Ting Wang, Jesse Kirkpatrick, Justin Rhoades, Todd R. Golub, J. Christopher Love, Viktor A. Adalsteinsson, Sangeeta N. Bhatia
Publikováno v:
bioRxiv
Liquid biopsies are enabling minimally invasive monitoring and molecular profiling of diseases across medicine, but their sensitivity remains limited by the scarcity of cell-free DNA (cfDNA) in blood. Here, we report an intravenous priming agent that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c820d25086601d81af5b242564adf344
https://doi.org/10.1101/2023.01.13.524003
https://doi.org/10.1101/2023.01.13.524003
Autor:
Shervin Tabrizi, Carmen Martin-Alonso, Kan Xiong, Timothy Blewett, Sainetra Sridhar, Zhenyi An, Sahil Patel, Sergio Rodriguez-Aponte, Christopher Naranjo, Douglas Shea, Todd Golub, Sangeeta N. Bhatia, Viktor A. Adalsteinsson, J. Christopher Love
Publikováno v:
Cancer Research. 83:3371-3371
Liquid biopsies using cell-free DNA (cfDNA) enable non-invasive detection and characterization of disease. Advances in sequencing methods have significantly improved the performance of liquid biopsies. Yet, despite these advances, sensitivity remains
Autor:
Carmen Martin-Alonso, Shervin Tabrizi, Kan Xiong, Ahmet Bekdemir Bekdemir, Sahil Patel, Zhenyi An, Timothy Blewett, Sainetra Sridhar, Douglas Shea, Ava Amini, Jesse D. Kirkpatrick, Jin Bae, Eugenia Roberts, Ruolin Liu, Justin Rhoades, Todd Golub, J. Christopher Love, Viktor A. Adalsteinsson, Sangeeta N. Bhatia
Publikováno v:
Cancer Prevention Research. 16:PR007-PR007
Liquid biopsy measurements, such as analysis of circulating tumor DNA (ctDNA) shed by cancer cells, have garnered significant attention for their potential to empower the field of precision oncology. Given that ctDNA tests could enable minimally inva
Autor:
Jin H. Bae, Douglas Shea, Todd R. Golub, Timothy Blewett, G. Mike Makrigiorgos, Erica Nguyen, Kan Xiong, Ruolin Liu, Justin Rhoades, Viktor A. Adalsteinsson
Publikováno v:
Nucleic Acids Research
Accurate DNA sequencing is crucial in biomedicine. Underlying the most accurate methods is the assumption that a mutation is true if altered bases are present on both strands of the DNA duplex. We now show that this assumption can be wrong. We establ