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pro vyhledávání: '"Timothy Bielecki"'
Autor:
Fany M Iseka, Benjamin Goetz, Luke R Cypher, Timothy Bielecki, Matthew Storck, Lee Mosely, Vimla Band, Hamid Band
Publikováno v:
The Journal of Immunology. 196:128.3-128.3
Regulatory mechanisms that ensure effective antigen-specific responses by T-cells without evoking autoimmune disease are of great interest in basic and clinical immunology. While signaling through T-cell receptor (TCR) and positive and negative co-re
Autor:
Fany Iseka, Benjamin Goetz, Luke Cypher, Timothy Bielecki, Matthew Storck, Vimla Band, Hamid Band
Publikováno v:
The Journal of Immunology. 194:61.12-61.12
The immunological synapse (IS) is a specialized membrane domain with localized display of T-cell receptor (TCR) in contact with a similar display of peptide-loaded MHC on antigen presenting cells (APCs). Aberrant IS function is linked to ineffective