Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Timothy B. Oriss"'
Autor:
Daniel P. Reay, Tracy Tabib, Ying Wang, Timothy B. Oriss, Nicholas A. Young, Robert A. Lafyatis, Wael N. Jarjour, Paula R. Clemens, Dana P. Ascherman
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionPrevious work in humans has demonstrated that both innate and adaptive immune signaling pathways contribute to the pathogenesis of idiopathic inflammatory myopathy (IIM), a systemic autoimmune disease targeting muscle as well as extra-mus
Externí odkaz:
https://doaj.org/article/3dbc331a3bdc494fb9d68eddf1837cd5
Autor:
Matthew J. Camiolo, Xiaoying Zhou, Timothy B. Oriss, Qi Yan, Michael Gorry, William Horne, John B. Trudeau, Kathryn Scholl, Wei Chen, Jay K. Kolls, Prabir Ray, Florian J. Weisel, Nadine M. Weisel, Nima Aghaeepour, Kari Nadeau, Sally E. Wenzel, Anuradha Ray
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108974- (2021)
Summary: Clinical definitions of asthma fail to capture the heterogeneity of immune dysfunction in severe, treatment-refractory disease. Applying mass cytometry and machine learning to bronchoalveolar lavage (BAL) cells, we find that corticosteroid-r
Externí odkaz:
https://doaj.org/article/c9fa672d9c7c4ce5951873f34b1a1ccf
Autor:
Krishnendu Chakraborty, Mahesh Raundhal, Bill B. Chen, Christina Morse, Yulia Y. Tyurina, Anupriya Khare, Timothy B. Oriss, Rachael Huff, Janet S. Lee, Claudette M. St. Croix, Simon Watkins, Rama K. Mallampalli, Valerian E. Kagan, Anuradha Ray, Prabir Ray
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Non-resolving bacterial pneumonia results in lung tissue damage owing to overactive inflammation. Here the authors show that the mitochondrial DAMP cardiolipin contributes to persistent inflammation by SUMOylating PPARγ, which promotes binding of th
Externí odkaz:
https://doaj.org/article/ed3074f4d02046868003319cc7c6eaff
Autor:
Anupriya Khare, Mahesh Raundhal, Krishnendu Chakraborty, Sudipta Das, Catherine Corey, Christelle K. Kamga, Kelly Quesnelle, Claudette St. Croix, Simon C. Watkins, Christina Morse, Timothy B. Oriss, Rachael Huff, Rachel Hannum, Prabir Ray, Sruti Shiva, Anuradha Ray
Publikováno v:
Cell Reports, Vol 15, Iss 8, Pp 1700-1714 (2016)
Inhalation of environmental antigens such as allergens does not always induce inflammation in the respiratory tract. While antigen-presenting cells (APCs), including dendritic cells and macrophages, take up inhaled antigens, the cell-intrinsic molecu
Externí odkaz:
https://doaj.org/article/e1541c0dfff848538266ffcb65fcb64e
Autor:
Mehdi Nouraie, Janet S. Lee, Yingze Zhang, Tamir Kanias, Xuejun Zhao, Zeyu Xiong, Timothy B. Oriss, Qilu Zeng, Gregory J. Kato, J. Simon R. Gibbs, Mariana E. Hildesheim, Vandana Sachdev, Robyn J. Barst, Roberto F. Machado, Kathryn L. Hassell, Jane A. Little, Dean E. Schraufnagel, Lakshmanan Krishnamurti, Enrico Novelli, Reda E. Girgis, Claudia R. Morris, Erika Berman Rosenzweig, David B. Badesch, Sophie Lanzkron, Oswaldo L. Castro, Jonathan C. Goldsmith, Victor R. Gordeuk, Mark T. Gladwin
Publikováno v:
Haematologica, Vol 98, Iss 3 (2013)
The intensity of hemolytic anemia has been proposed as an independent risk factor for the development of certain clinical complications of sickle cell disease, such as pulmonary hypertension, hypoxemia and cutaneous leg ulceration. A composite variab
Externí odkaz:
https://doaj.org/article/6186f62dfbe0472a8d73981f8e61f9fb
Autor:
Huijuan Yuan, Sudipta Das, Anuradha Ray, Sanmei Hu, Seyed Mehdi Nouraie, Sagar Laxman Kale, Jie Chen, Prabir Ray, Timothy B. Oriss
Publikováno v:
Mucosal Immunology. 15:154-164
Immune tolerance to allergens in early-life decreases the risk for asthma in later life. Here we show establishment of stable airway tolerance to the allergen, house dust mite (HDM), by exposing newborn mice repeatedly to a low dose of the allergen.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f7bb88ca1e0bc86875d5ce225d8a73d
https://doi.org/10.1038/s41385-021-00458-8
https://doi.org/10.1038/s41385-021-00458-8
Publikováno v:
Curr Opin Immunol
Asthma as a clinical entity manifests with a broad spectrum of disease severity. Unlike milder asthma, severe disease is poorly controlled by inhaled corticosteroids, the current standard of care. Transcriptomic data, along with patient characteristi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc3db9757a1b1336acfc6a5331e241c
https://doi.org/10.1016/j.coi.2021.03.004
https://doi.org/10.1016/j.coi.2021.03.004
Autor:
Marc Gauthier, Sagar Laxman Kale, Timothy B. Oriss, Michael Gorry, Richard P. Ramonell, Kathryn Dalton, Prabir Ray, John V. Fahy, Max A. Seibold, Mario Castro, Nizar Jarjour, Benjamin Gaston, Eugene R. Bleecker, Deborah A. Meyers, Wendy Moore, Annette T. Hastie, Elliot Israel, Bruce D. Levy, David Mauger, Serpil Erzurum, Suzy A. Comhair, Sally E. Wenzel, Anuradha Ray
Publikováno v:
Journal of Allergy and Clinical Immunology. 151:AB224
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0d9667d00db230feee95f0158b2f715
https://doi.org/10.1016/j.jaci.2022.12.696
https://doi.org/10.1016/j.jaci.2022.12.696
Autor:
Huijuan, Yuan, Jie, Chen, Sanmei, Hu, Timothy B, Oriss, Sagar Laxman, Kale, Sudipta, Das, Seyed M, Nouraie, Prabir, Ray, Anuradha, Ray
Publikováno v:
Mucosal immunology. 15(1)
Immune tolerance to allergens in early-life decreases the risk for asthma in later life. Here we show establishment of stable airway tolerance to the allergen, house dust mite (HDM), by exposing newborn mice repeatedly to a low dose of the allergen.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::67ab964ca9cfd53e8ab8faea4ef56fd5
https://pubmed.ncbi.nlm.nih.gov/34580428
https://pubmed.ncbi.nlm.nih.gov/34580428
Autor:
Sally E. Wenzel, Qi Yan, Florian Weisel, Matthew J. Camiolo, Xiaoying Zhou, Nadine M. Weisel, Timothy B. Oriss, Nima Aghaeepour, Kathryn Scholl, Jay K. Kolls, John B. Trudeau, Wei Chen, Kari C. Nadeau, William Horne, Anuradha Ray, Prabir Ray, Michael C. Gorry
Publikováno v:
Cell reports
Cell Reports, Vol 35, Iss 2, Pp 108974-(2021)
Cell Reports, Vol 35, Iss 2, Pp 108974-(2021)
SUMMARY Clinical definitions of asthma fail to capture the heterogeneity of immune dysfunction in severe, treatment-refractory disease. Applying mass cytometry and machine learning to bronchoalveolar lavage (BAL) cells, we find that corticosteroid-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46efed04eba8dab961864e3ad105a5da
https://pubmed.ncbi.nlm.nih.gov/33852838
https://pubmed.ncbi.nlm.nih.gov/33852838