Výsledky vyhledávání - "Timothy B. Miller"

A Hypervariable Region within the 3′ cis -Acting Element of the Murine Coronavirus Genome Is Nonessential for RNA Synthesis but Affects Pathogenesis

Autor: Timothy B. Miller, Kristen A. Bernard, Paul S. Masters, Scott J. Goebel, Corey J. Bennett

Publikováno v: Journal of Virology

The 3′ cis -acting element for mouse hepatitis virus (MHV) RNA synthesis resides entirely within the 301-nucleotide 3′ untranslated region (3′ UTR) of the viral genome and consists of three regions. Encompassing the upstream end of the 3′ UTR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9883292cc8c641963eaefecaf0606f14
https://doi.org/10.1128/jvi.00803-06

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Magnetic Resonance Elastography of the Plantar Fat Pads

Autor: Marvin M. Doyley, Francis E. Kennedy, James S. Wrobel, Yvonne Y. Cheung, Timothy B. Miller, Franklin Lynch, Keith Paulson, John B. Weaver

Publikováno v: Journal of Computer Assisted Tomography. 30:321-326

Objective To test the feasibility of applying the magnetic resonance elastography (MRE) technique to map the elastic modulus of the plantar fat pads in diabetic and nondiabetic subjects. Methods A prototype MRE imaging apparatus was used to produce q

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1ffc0019f5ddc63b97f253dffa413ea
https://doi.org/10.1097/00004728-200603000-00031

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Cutting Edge: Virus-Specific CD4+ Memory T Cells in Nonlymphoid Tissues Express a Highly Activated Phenotype

Autor: Dario A. A. Vignali, Pamela S. Adams, David L. Woodland, Timothy B. Miller, Tres Cookenham, Linda S. Cauley, Kate M. Vignali

Publikováno v: The Journal of Immunology. 169:6655-6658

Recent studies have shown that CD4+ memory T cells persist in nonlymphoid organs following infections. However, the development and phenotype of these peripheral memory cells are poorly defined. In this study, multimerized MHC-Ig fusion proteins, wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd636930727e593edb1a282070e5c99
https://doi.org/10.4049/jimmunol.169.12.6655

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Reliable generation and use of MHC class II:γ2aFc multimers for the identification of antigen-specific CD4+ T cells

Autor: Dario A. A. Vignali, Paula Y. Arnold, Timothy B. Miller, Linda S. Cauley, Laura Haynes, Kate M. Vignali, Susan L. Swain, Nicole L. La Gruta, P. Scott Adams, David L. Woodland

Publikováno v: Journal of Immunological Methods. 271:137-151

MHC tetramers have proven to be powerful reagents for the analysis of MHC class I-restricted T cells. However, generating similarly reliable reagents for MHC class II-restricted T cells has been elusive. Here we evaluated the utility of MHC class II:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebb54c178c983cd0cc487069c4671160
https://doi.org/10.1016/s0022-1759(02)00343-5

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Genetic Interactions between an Essential 3′ cis-Acting RNA Pseudoknot, Replicase Gene Products, and the Extreme 3′ End of the Mouse Coronavirus Genome▿

Autor: Paul S. Masters, Roland Züst, Volker Thiel, Timothy B. Miller, Scott J. Goebel

Publikováno v: Journal of Virology

The upstream end of the 3′ untranslated region (UTR) of the mouse hepatitis virus genome contains two essential and overlapping RNA secondary structures, a bulged stem-loop and a pseudoknot, which have been proposed to be elements of a molecular sw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b6654a6f95a3164178746908d361ed
https://europepmc.org/articles/PMC2224451/

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Reproducibility of MRE shear modulus estimates

Autor: Huifang Wang, P. R. Perrinez, Timothy B. Miller, Yvonne Y. Cheung, Marvin D. Doyley, Keith D. Paulsen, John B. Weaver, Francis E. Kennedy

Publikováno v: SPIE Proceedings.

A significant effort has been expended to measure the accuracy of the shear modulus estimates. Conversely, very little effort has been expended to establish the reproducibility of the method in a clinical context. Previously we established the reprod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf28e960b53770e56bcc14c621c8a0d1
https://doi.org/10.1117/12.713772

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MR elastographic methods for the evaluation of plantar fat pads: preliminary comparison of the shear modulus for shearing deformation and compressive deformation in normal subjects

Autor: James S. Wrobel, John B. Weaver, Philip R. Perrinez, Richard J. Comi, Timothy B. Miller, Marvin M. Doyley, Huifang Wang, Yvonne Y. Cheung, Francis E. Kennedy, Keith D. Paulsen

Publikováno v: SPIE Proceedings.

MR elastography (MRE) images the intrinsic mechanical properties of soft tissues; e.g., the shear modulus, μ. The μ of the plantar soft tissues is important in understanding the mechanisms whereby the forces induced during normal motion produce ulc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::44ab90a12672c4395a940e2eae15af8f
https://doi.org/10.1117/12.652828

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The Majority of Immunogenic Epitopes Generate CD4+ T Cells That Are Dependent on MHC Class II-Bound Peptide-Flanking Residues

Autor: David L. Woodland, Kate M. Vignali, Paula Y. Arnold, Timothy B. Miller, Nicole L. La Gruta, P. Scott Adams, Dario A. A. Vignali

Publikováno v: The Journal of Immunology. 169:4674-4674

Peptides bind to MHC class II molecules with a defined periodicity such that the peptide-flanking residues (PFRs) P-1 and P11, which lie outside the core binding sequence (P1–P9), are solvent exposed and accessible to the TCR. Using a novel MHC cla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8d651b8ab48c07ad2bbeaa5e6a0d38
https://doi.org/10.4049/jimmunol.169.8.4674-a

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