Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Timothy B. Branigan"'
Autor:
Ryan D. Mouery, Kimberly Lukasik, Carolyn Hsu, Thomas Bonacci, Derek L. Bolhuis, Xianxi Wang, C. Allie Mills, E. Drew Toomer, Owen G. Canterbury, Kevin C. Robertson, Timothy B. Branigan, Nicholas G. Brown, Laura E. Herring, Stephanie L. Gupton, Michael J. Emanuele
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114510- (2024)
Summary: Ubiquitination is an essential regulator of cell division. The kinase Polo-like kinase 1 (PLK1) promotes protein degradation at G2/M phase through the E3 ubiquitin ligase Skp1-Cul1-F box (SCF)βTrCP. However, the magnitude to which PLK1 shap
Externí odkaz:
https://doaj.org/article/43e0cb2829ad40e78a39e529e1e2c616
Autor:
Rajarshi Choudhury, Thomas Bonacci, Anthony Arceci, Debojyoti Lahiri, Christine A. Mills, Jennifer L. Kernan, Timothy B. Branigan, James A. DeCaprio, Daniel J. Burke, Michael J. Emanuele
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113974- (2024)
Externí odkaz:
https://doaj.org/article/e9392c2bf406451da92c8591228d6143
Autor:
Rajarshi Choudhury, Thomas Bonacci, Anthony Arceci, Debojyoti Lahiri, Christine A. Mills, Jennifer L. Kernan, Timothy B. Branigan, James A. DeCaprio, Daniel J. Burke, Michael J. Emanuele
Publikováno v:
Cell Reports, Vol 16, Iss 12, Pp 3359-3372 (2016)
The anaphase promoting complex/cyclosome (APC/C) is an ubiquitin ligase and core component of the cell-cycle oscillator. During G1 phase, APC/C binds to its substrate receptor Cdh1 and APC/CCdh1 plays an important role in restricting S-phase entry an
Externí odkaz:
https://doaj.org/article/3fc26f609f7b4e259bca21c4e17e3a52
Publikováno v:
Trends in Biochemical Sciences. 47:1009-1022
Cell cycle-dependent gene transcription is tightly controlled by the retinoblastoma (RB):E2F and DREAM complexes, which repress all cell cycle genes during quiescence. Cyclin-dependent kinase (CDK) phosphorylation of RB and DREAM allows for the expre
Autor:
Jan M. Suski, Nalin Ratnayeke, Marcin Braun, Tian Zhang, Vladislav Strmiska, Wojciech Michowski, Geylani Can, Antoine Simoneau, Konrad Snioch, Mikolaj Cup, Caitlin M. Sullivan, Xiaoji Wu, Joanna Nowacka, Timothy B. Branigan, Lindsey R. Pack, James A. DeCaprio, Yan Geng, Lee Zou, Steven P. Gygi, Johannes C. Walter, Tobias Meyer, Piotr Sicinski
Publikováno v:
Nature
Entry of mammalian cells into DNA synthesis (S-phase) represents a key event in cell division(1). According to the current cell-cycle models, the Cdc7 kinase constitutes an essential and rate-limiting trigger of DNA replication, acting together with