Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Timothy Alefantis"'
Autor:
Ted M. Ross, Donald M. Carter, Timothy Alefantis, Terianne M. Wong, Anne-Gaelle Bebin-Blackwell, Joshua M. DiNapoli, James D. Allen, Harold Kleanthous
Each influenza season, a set of wild-type viruses, representing one H1N1, one H3N2, and one to two influenza B isolates, are selected for inclusion in the annual seasonal influenza vaccine. In order to develop broadly reactive subtype-specific influe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a3d35c74a5ec95fa843dc6f485d89f
https://europepmc.org/articles/PMC5709590/
https://europepmc.org/articles/PMC5709590/
Autor:
Timothy Alefantis, Svetlana Stegalkina, Mujing Fang, Junyu Chen, Honglin Chen, Xiaoyang Cai, Quan Yuan, Ningshao Xia, Wang Guosong, Zhang Limin, Hai Yu, Yixin Chen, Jing Chen, Minwei Zhang, Wenxin Luo, Chenguang Shen, Zizheng Zheng, Xingjian Bi, Kunyu Yang, Jian-Li Cao, Rui Li, James Wai-Kuo Shih, Zhang Mengya, Harry Kleanthous, Stephen Anderson, Jun Zhang, Qingbing Zheng
Publikováno v:
Science Translational Medicine. 9
Influenza B virus causes considerable disease burden worldwide annually, highlighting the limitations of current influenza vaccines and antiviral drugs. In recent years, broadly neutralizing antibodies (bnAbs) against hemagglutinin (HA) have emerged
Autor:
Tod Strugnell, Harold Kleanthous, Ted M. Ross, Stephen Anderson, Thorsten U. Vogel, Raymond P. Oomen, Corey J. Crevar, Timothy Alefantis, Mark Parrington, Donald M. Carter, Bradford C. Lefoley, Guadalupe Cortes-Garcia, Christopher A. Darby
Publikováno v:
Journal of virology. 90(9)
One of the challenges of developing influenza A vaccines is the diversity of antigenically distinct isolates. Previously, a novel hemagglutinin (HA) for H5N1 influenza was derived from a methodology termed computationally optimized broadly reactive a
Autor:
Brian Wigdahl, Joel Martin, Timothy Alefantis, Edward W. Harhaj, Christian Grant, Jing Yao, Michael R. Nonnemacher, Pooja Jain
Publikováno v:
DNA and Cell Biology. 25:262-276
Transcription factors of the Sp family are known to play key roles in the regulation of both constitutive as well as cell type- and differentiation stage-specific gene expression. Binding sites for factors of the Sp family (Sp1 and Sp3) have previous
Autor:
Christian Grant, Brian Wigdahl, Edward W. Harhaj, Timothy Alefantis, Kate Mostoller, Pooja Jain
Publikováno v:
Journal of Biological Chemistry. 280:17353-17362
Human T cell leukemia virus type I (HTLV-I) is the etiologic agent of adult T cell leukemia and HTLV-I-associated myelopathy/tropical spastic paraparesis. The HTLV-I protein Tax is well known as a transcriptional transactivator and inducer of cellula
Autor:
Kate Mostoller, Nicole S. Harhaj, Shao Cong Sun, Christian Grant, Brian Wigdahl, Edward W. Harhaj, Timothy Alefantis
Publikováno v:
Virology. 333:145-158
The human T cell leukemia virus type I (HTLV-I) is an oncogenic retrovirus that is etiologically linked to the genesis of adult T cell leukemia (ATL) as well as HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Emerging evidence su
Publikováno v:
Virology. 308(1):1-12
Retroviral infection is associated with a number of pathologic abnormalities, including a variety of cancers, immunologic diseases, and neurologic disorders. Shortly after its discovery in 1980, human T cell leukemia virus type I (HTLV-I) was found t
Publikováno v:
Journal of Cellular Physiology. 190:133-159
Human T cell lymphotropic/leukemia virus type I (HTLV-I) has been identified as the causative agent of both adult T cell leukemia (ATL) and HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Although the exact sequence of events tha
Autor:
Zafar K. Khan, Brian Wigdahl, Pooja Jain, Timothy Alefantis, Kate Mostoller, Jaya Ahuja, Veronique Lepoutre, Katherine E. Flaig
Publikováno v:
The Journal of biological chemistry. 282(47)
Human T cell leukemia virus type 1 (HTLV-1) is the etiologic agent of a number of pathologic abnormalities, including adult T cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The viral oncoprotein Tax has b
Publikováno v:
Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 61(4)
Human T cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The HTLV-1 transcriptional transactivator protein Tax plays an integral role in