Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Timothy A. Watkins"'
Publikováno v:
mBio, Vol 15, Iss 7 (2024)
ABSTRACT When respiratory viruses co-circulate in a population, individuals may be infected with multiple pathogens and experience possible virus–virus interactions, where concurrent or recent prior infection with one virus affects the infection pr
Externí odkaz:
https://doaj.org/article/0a5a803e8eb243649a985dad4c6c40c7
Autor:
Kristin L. Boswell, Timothy A. Watkins, Evan M. Cale, Jakob Samsel, Sarah F. Andrews, David R. Ambrozak, Jefferson I. Driscoll, Michael A. Messina, Sandeep Narpala, Christine S. Hopp, Alberto Cagigi, Joseph P. Casazza, Takuya Yamamoto, Tongqing Zhou, William R. Schief, Peter D. Crompton, Julie E. Ledgerwood, Mark Connors, Lucio Gama, Peter D. Kwong, Adrian McDermott, John R. Mascola, Richard A. Koup
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The isolation and characterization of neutralizing antibodies from infection and vaccine settings informs future vaccine design, and methodologies that streamline the isolation of antibodies and the generation of B cell clones are of great interest.
Externí odkaz:
https://doaj.org/article/5545d1b2bd774ffa82a9c22a398ffe25
Autor:
Islam Younis, Elijah Weber, Cara Nelson, Brian J. Kirby, Gong Shen, Deqing Xiao, Timothy R. Watkins, Ahmed A. Othman
Publikováno v:
Clinical Pharmacokinetics. 62:609-621
Autor:
Elijah Weber, Islam R. Younis, Cara Nelson, Dora Ding, Ann Qin, Deqing Xiao, Timothy R. Watkins, Ahmed A. Othman
Publikováno v:
The Journal of Clinical Pharmacology. 63:560-568
Autor:
Islam R. Younis, Brian J. Kirby, Andrew N. Billin, Deqing Xiao, Qinghua Song, Timothy R. Watkins, Ahmed A. Othman
Publikováno v:
Clinical and Translational Science. 16:536-547
Cilofexor is a nonsteroidal farnesoid X receptor (FXR) agonist being evaluated for treatment of nonalcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC). This work characterized the pharmacokinetics, pharmacodynamic, safety, and t
Autor:
Nagarjuna R, Cheemarla, Amelia, Hanron, Joseph R, Fauver, Jason, Bishai, Timothy A, Watkins, Anderson F, Brito, Dejian, Zhao, Tara, Alpert, Chantal B F, Vogels, Albert I, Ko, Wade L, Schulz, Marie L, Landry, Nathan D, Grubaugh, David, van Dijk, Ellen F, Foxman
Publikováno v:
The Lancet Microbe. 4:e38-e46
Symptomatic patients who test negative for common viruses are an important possible source of unrecognised or emerging pathogens, but metagenomic sequencing of all samples is inefficient because of the low likelihood of finding a pathogen in any give
Autor:
Islam R. Younis, Chia‐Hsiang Hsueh, Cara Nelson, Andrew N. Billin, Mun Sang Yue, Deqing Xiao, Timothy R. Watkins, Ahmed A. Othman
Publikováno v:
The Journal of Clinical Pharmacology.
Autor:
Wayne J. G. Hellstrom, Radboud J. E. M. Dolhain, Timothy E. Ritter, Timothy R. Watkins, Sarah J. Arterburn, Goele Dekkers, Angi Gillen, Caroline Tonussi, Leen Gilles, Alessandra Oortwijn, Katrien Van Beneden, Dick E. de Vries, Suresh C. Sikka, Dirk Vanderschueren, Walter Reinisch
Publikováno v:
Advances in Therapy, 39(7), 3403-3422. Springer International Publishing AG
INTRODUCTION: The phase 2 MANTA and MANTA-RAy studies were developed in consultation with global regulatory authorities to investigate potential impacts of filgotinib, a Janus kinase 1 preferential inhibitor, on semen parameters in men with active in
Autor:
Janani S. Iyer, Harsha Pokkalla, Charles Biddle-Snead, Oscar Carrasco-Zevallos, Mary Lin, Zahil Shanis, Quang Le, Dinkar Juyal, Maryam Pouryahya, Aryan Pedawi, Sara Hoffman, Hunter Elliott, Kenneth Leidal, Robert P. Myers, Chuhan Chung, Andrew N. Billin, Timothy R. Watkins, Murray Resnick, Katy Wack, Jon Glickman, Alastair D. Burt, Rohit Loomba, Arun J. Sanyal, Michael C. Montalto, Andrew H. Beck, Amaro Taylor-Weiner, Ilan Wapinski
Clinical trials in nonalcoholic steatohepatitis (NASH) require histologic scoring for assessment of inclusion criteria and endpoints. However, guidelines for scoring key features have led to variability in interpretation, impacting clinical trial out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf4e90e1edfaeb039c78c57d3af13b08
https://doi.org/10.1101/2023.04.20.23288534
https://doi.org/10.1101/2023.04.20.23288534
Publikováno v:
bioRxiv
The resurgence of influenza and continued circulation of SARS-CoV-2 raise the question of how these viruses interact in a co-exposed host. Here we studied virus-virus and host-virus interactions during influenza A virus (IAV) -SARS-CoV-2 coinfection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af626099a1ac837522e8ec8e8e066a3c
https://europepmc.org/articles/PMC9934525/
https://europepmc.org/articles/PMC9934525/