Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Timothy A. Lyerla"'
Publikováno v:
The Biological bulletin. 149(1)
Some chemical properties of the orange pigment from eggs and embryos and the mantle tissue of adult Ecteinascidia turbinata, as well as ultrastructural characteristics of pigment masses in the mantle, have been examined. The diffuse egg and embryo pi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb90e4ef229592e899a33c11fd3238e1
https://pubmed.ncbi.nlm.nih.gov/29323968
https://pubmed.ncbi.nlm.nih.gov/29323968
Autor:
Timothy A. Lyerla, Lingyan Wang
Publikováno v:
Histochemistry and Cell Biology
Hermansky Pudlak syndrome (HPS) is a heterogeneous recessive genetic disease with a tendency to develop lung fibrosis with aging. A mouse strain with two mutant HPS genes affecting separate vesicle trafficking pathways, C57BL/6-Hps1 ( ep )-Ap3b1 ( pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c2e3a2f7814e74b78d958d2c2c303b4
https://doi.org/10.1007/s00418-010-0724-8
https://doi.org/10.1007/s00418-010-0724-8
Autor:
Timothy A. Lyerla, Steven G. Davis
Publikováno v:
Experimental Cell Research. 237:242-245
The beige mutant in the mouse is characterized by enlarged lysosomes in many cell types due to increased fluidity of cellular membranes and organelle fusion. In this study, mutant fibroblasts derived from C57BL/ 6J;bgJ/bgJ animals were compared with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006f4034770ecf239898a4d4f30fdd55
https://doi.org/10.1006/excr.1997.3767
https://doi.org/10.1006/excr.1997.3767
Autor:
Timothy A. Lyerla, Joseph Yeretsian, Edwin H. Kolodny, Samir D. Undevia, Strutha C. Rouse, Rita De Gasperi, Miguel A. Gama Sosa
Publikováno v:
Biochemical and Biophysical Research Communications. 218:766-771
Globoid cell leukodystrophy (GCL) or Krabbe disease is an autosomal recessive inherited disease caused by the deficiency of galactocerebrosidase, the lysosomal enzyme responsible for the degradation of galactocerebroside, a major component of myelin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::981d305aaa00a827d3e176e48b6e4097
https://doi.org/10.1006/bbrc.1996.0136
https://doi.org/10.1006/bbrc.1996.0136
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 29:884-891
Fibroblasts from a beige mouse (C57BL/6J; bgJ bgJ) have been established and maintained in culture for more than 3 yr. At early passages, the mutant cells were distinguishable from C57BL/6J control mouse fibroblasts at the ultrastructural level by th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70969f34bf9022df8b400b45920926b9
https://doi.org/10.1007/bf02631368
https://doi.org/10.1007/bf02631368
Publikováno v:
Molecular and Cellular Biochemistry. 118:61-66
In the normal C57BL/6J male mouse a specific subset of the kidney glycosphingolipids which is associated with multilamellar bodies of lysosomal origin and represents about 10% of the total kidney glycolipids, is excreted into the urine each day. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3d747ae1df2209153ae4f904c57501
https://doi.org/10.1007/bf00249695
https://doi.org/10.1007/bf00249695
Publikováno v:
Journal of Neuroscience Research. 27:472-478
The inherited deficiency of galactosylceramide beta-galactosidase (E.C. 3.2.1.46: galactocerebrosidase) activity results in globoid cell leukodystrophy in humans (Krabbe disease) and in mice (twitcher mutant). To determine whether Krabbe patients' ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f4510e39d88408ff8d95474f51725a
https://doi.org/10.1002/jnr.490270406
https://doi.org/10.1002/jnr.490270406
Publikováno v:
Experimental cell research. 256(1)
The hypopigment mutant mice, light ear, pallid, and beige, possess defects in melanosomes, lysosomes, and platelet dense granules, suggesting that these organelles share a common biogenesis and processing. Light ear and pallid mutants are animal mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3a37b376ce955de6f5c267394d95fa
https://pubmed.ncbi.nlm.nih.gov/10739679
https://pubmed.ncbi.nlm.nih.gov/10739679
Publikováno v:
Pigment Cell Research. 3:123-125
The yellow pigment observed in older axanthic (ax/ax) mutant Mexican axolotls (Ambystoma mexicanum) was analyzed by thin layer chromatography and by spectrofluorometry of its acetyl derivative. Ethanol extracts from the skin of axanthic animals were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8d254666d0466b55315aceb9136b88
https://doi.org/10.1111/j.1600-0749.1990.tb00275.x
https://doi.org/10.1111/j.1600-0749.1990.tb00275.x
Publikováno v:
In vitro cellulardevelopmental biology. Animal. 32(8)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f797f9154bfc32fb0c3c7310691d535
https://pubmed.ncbi.nlm.nih.gov/8889598
https://pubmed.ncbi.nlm.nih.gov/8889598