Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Timothy A. Katte"'
Autor:
Damien W. Gulliver, Tristan A. Reekie, William T. Jorgensen, Eryn L. Werry, Timothy A. Katte, Michael Kassiou
Publikováno v:
Trends in Pharmacological Sciences. 40:22-37
Deficits in social behavioral domains, such as interpersonal communication, emotion recognition, and empathy, are a characteristic symptom in several neuropsychiatric disorders, including schizophrenia and autism spectrum disorder (ASD). The neuropep
Autor:
Michelle L. Halls, Julie Sanchez, Claudia Alamein, Meritxell Canals, Alexander Gillis, Frank Schmiedel, J. Robert Lane, Tristan A. Reekie, Preeti Manandhar, Michael Kassiou, Mark Connor, Andrea Kliewer, MacDonald J. Christie, Arisbel B. Gondin, Timothy A. Katte, Marina Santiago, Cornelius Krasel, Herman D. Lim, Stefan Schulz, Natasha L. Grimsey, Barrie Kellam, Sebastian Fritzwanker
Publikováno v:
Science signaling. 13(625)
Biased agonism at G protein–coupled receptors describes the phenomenon whereby some drugs can activate some downstream signaling activities to the relative exclusion of others. Descriptions of biased agonism focusing on the differential engagement
Autor:
Mark Connor, Eryn L. Werry, Damien W. Gulliver, William T. Jorgensen, Timothy A. Katte, Michael Kassiou, Tristan A. Reekie
Publikováno v:
European Journal of Medicinal Chemistry. 143:1644-1656
WAY-267,464 (1) and twelve conformationally rigid analogues (3a-f–4a-f) were synthesised, characterised and evaluated in cellular assays with the aim of systematically exploring interactions with the oxytocin receptor (OTR). Each analogue was evalu
Publikováno v:
The Journal of Organic Chemistry. 81:4883-4889
Reported is a method for the synthesis of seven-membered heterocycles via a Pictet-Spengler condensation reaction under very mild conditions. High substrate scope allows for use of aldehydes using catalytic amounts of acetic acid yielding 39-90% and
Autor:
Timothy A. Katte, Michael Kassiou
Publikováno v:
Expert opinion on therapeutic patents. 27(12)
Autor:
Timothy A. Katte, Michael Kassiou, Eryn L. Werry, Mark Connor, Rochelle Boyd, William T. Jorgensen, Erick C.N. Wong, Tristan A. Reekie, Damien W. Gulliver
Publikováno v:
European journal of medicinal chemistry. 136
The neuropeptide oxytocin has been implicated in multiple central nervous system functions in mammalian species. Increased levels have been reported to improve trust, alleviate symptoms related to autism and social phobias, and reduce social anxiety.
Publikováno v:
ChemInform. 47
Reported is a method for the synthesis of seven-membered heterocycles via a Pictet–Spengler condensation reaction under very mild conditions. High substrate scope allows for use of aldehydes using catalytic amounts of acetic acid yielding 39–90%
Autor:
Michael Kassiou, William T. Jorgensen, Tristan A. Reekie, Timothy A. Katte, Damien W. Gulliver, Eryn L. Werry
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. :PO4-1