Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Timothy A. Cudd"'
Publikováno v:
Alcohol
Individuals with fetal alcohol spectrum disorders (FASD) incur enduring brain damage and neurodevelopmental impairments from prenatal alcohol exposure (PAE). Preclinical rodent models have demonstrated that choline supplementation during development
Autor:
Emily Lunde, Shannon E. Washburn, Timothy A. Cudd, Kelsey Nation, Adam Birge, Charles R. Goodlett
Publikováno v:
Behavior Research Methods. 49:1838-1851
Pavlovian eye blink conditioning (EBC) has been extensively studied in humans and laboratory animals, providing one of the best-understood models of learning in neuroscience. EBC has been especially useful in translational studies of cerebellar and h
Publikováno v:
Brain Injury. 29:104-109
Pre-natal alcohol exposure results in injury to the hippocampus and olfactory bulb,but currently there is no consensus on the critical window of vulnerability. This study tested thehypothesis that pre-natal exposure to a moderate dose of alcohol duri
Publikováno v:
Alcohol. 47:53-61
Women who drink alcohol during pregnancy are at high risk of giving birth to children with neurodevelopmental disorders. Previous reports from our laboratory have shown that third trimester equivalent binge alcohol exposure at a dose of 1.75 g/kg/day
Publikováno v:
Developmental Psychobiology. 54:785-797
A major advantage of sheep models in experimental studies of neurodevelopmental disorders (e.g., with prenatal neurotoxicant exposure) is that the equivalent of all three trimesters of human brain development occurs in sheep entirely in utero. Howeve
Autor:
Thomas E. Spencer, M. Carey Satterfield, Duane H. Keisler, Guoyao Wu, Fuller W. Bazer, Sujay Datta, Timothy A. Cudd, Arantzatzu Lassala
Publikováno v:
The Journal of Nutrition. 141:849-855
The frequency of multiple fetuses has increased in human pregnancies due to assisted reproductive technologies. This translates into a greater proportion of premature and low-birth weight infants in the United States and worldwide. In addition, impro
Autor:
Thomas E. Spencer, Sujay Datta, Guoyao Wu, M. Carey Satterfield, Fuller W. Bazer, Duane H. Keisler, Arantzatzu Lassala, Timothy A. Cudd
Publikováno v:
The Journal of Nutrition. 140:1242-1248
Intrauterine growth restriction (IUGR) is a major health problem worldwide that currently lacks an effective therapeutic solution. This study was conducted with an ovine IUGR model to test the hypothesis that parenteral administration of L-arginine (
Publikováno v:
Alcohol. 42:657-666
Heavy drinking during pregnancy can result in fetal alcohol syndrome (FAS), of which, fetal and postnatal growth retardation and central nervous system deficits are cardinal features. Although a number of mechanisms have been proposed, none fully acc
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 295:R596-R603
Ethanol is now considered the most common human teratogen. Educational campaigns have not reduced the incidence of ethanol-mediated teratogenesis, leading to a growing interest in the development of therapeutic prevention or mitigation strategies. On
Publikováno v:
Alcohol. 42:199-205
Alcohol-mediated alterations in hypothalamic-pituitary-adrenal (HPA) and hypothalamic-pituitary-thyroid axis function are two proposed mechanisms by which alcohol causes neurodevelopmental injury to the fetus. We previously reported that third-trimes