Zobrazeno 1 - 10
of 358
pro vyhledávání: '"Timothy A. Cross"'
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract The SARS-CoV-2 E protein is a transmembrane (TM) protein with its N-terminus exposed on the external surface of the virus. At debate is its oligomeric state, let alone its function. Here, the TM structure of the E protein is characterized by
Externí odkaz:
https://doaj.org/article/71abbf15a76d4f70bb07cb625b1ef677
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
The disordered cytoplasmic region of Mtb FtsQ can interact with three partners – the upstream acidic residues in solution, the inner membrane surface, and the GTPase domain of FtsZ – suggesting its role in cell division and as a drug target.
Externí odkaz:
https://doaj.org/article/8a3788e0e42d4d94bfdc97574be0fd0e
Publikováno v:
Magnetic Resonance Letters, Vol 1, Iss 2, Pp 99-111 (2021)
Water plays an important role in many essential biological processes of membrane proteins in hydrated lipid environments. In general, the 1H polarization transfers between water molecules and site-specific protons in proteins can be classified as coh
Externí odkaz:
https://doaj.org/article/8d683dc104c24c1ab151c36e9c7ff127
Publikováno v:
JACS Au, Vol 1, Iss 1, Pp 66-78 (2020)
Externí odkaz:
https://doaj.org/article/72fd8e89fe294b1aa2dbaa224f74bb79
Publikováno v:
Biomolecules, Vol 10, Iss 6, p 946 (2020)
How sequences of intrinsically disordered proteins (IDPs) code for their conformational dynamics is poorly understood. Here, we combined NMR spectroscopy, small-angle X-ray scattering (SAXS), and molecular dynamics (MD) simulations to characterize th
Externí odkaz:
https://doaj.org/article/22d6a5aa00014b01b4f455aa301e57cb
Publikováno v:
Canadian Journal of Fisheries and Aquatic Sciences. 79:1120-1137
Scale and hierarchy have received less attention in aquatic compared to terrestrial systems. Walleye (Sander vitreus) spawning habitat offers an opportunity to investigate scale’s importance. We estimated lake-, transect-, and quadrat-scale influen
Publikováno v:
J Am Chem Soc
Understanding water dynamics and structure is an important topic in biological systems. It is generally held in the literature that the interfacial water of hydrated phospholipids is highly mobile, in fast exchange with the bulk water ranging from th
Autor:
Katherine Cullen, Mari Jones, Rhys D. Pockett, Anya Burton, Timothy J.S. Cross, Ian A. Rowe, Lizz Paley, Daniela Tataru, Graeme Alexander, Aileen Marshall, Deborah Fitzsimmons
ObjectiveHepatocellular carcinoma (HCC) incidence in the UK trebled between 1997 and 2017. With increasing numbers requiring treatment, understanding the likely impact on healthcare budgets can inform service planning and commissioning. The aim of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79f81d52b118c2fceab49f8d3a3643aa
https://cronfa.swan.ac.uk/Record/cronfa63143/Download/63143__27431__ea7b4d65f6af4e0cbec675c934d79153.pdf
https://cronfa.swan.ac.uk/Record/cronfa63143/Download/63143__27431__ea7b4d65f6af4e0cbec675c934d79153.pdf
Publikováno v:
Magnetic Resonance Letters. 1:99-111
Mycobacteria tuberculosis (Mtb)inflicts a quarter of the worldwide population. Most drugs for treating tuberculosis target cell growth and division. With rising drug resistance, it becomes ever more urgent to better understandMtbcell division. This p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34cdbbea4ab548e5272dec7db5142ea6
https://doi.org/10.1101/2022.09.02.506397
https://doi.org/10.1101/2022.09.02.506397