Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Timothy A. Blauwkamp"'
Autor:
Timothy A. Blauwkamp, Desiree Hollemon, Lily Blair, Douglas E. Padgett, Andy O. Miller, Thomas W. Bauer, Peter K. Sculco, Barry D. Brause, Michael B. Cross, Alexandra Grizas, Laura T. Donlin, Ian S. Cohn, Christopher E. Mason, Geoffrey H. Westrich, Matthew S. Hepinstall, Lionel B. Ivashkiv, Adriana P. Echeverria, Susan M. Goodman, Alberto V Carli, Christine Mironenko, Mathias P.G. Bostrom, Carine Ho, Mark P. Figgie, David K. Hong, David Danko, Galit Meshulam-Simon, Sara Shanaj, Michael W. Henry, Asim A. Ahmed, Thomas P. Sculco
Publikováno v:
Journal of Bone and Joint Surgery. 103:1705-1712
Background Over 1 million Americans undergo joint replacement each year, and approximately 1 in 75 will incur a periprosthetic joint infection. Effective treatment necessitates pathogen identification, yet standard-of-care cultures fail to detect org
Autor:
Lily Blair, David K. Hong, Terry Stevens-Ayers, Joyce Maalouf, Michael Boeckh, Asim A. Ahmed, Joshua A. Hill, Sudeb C. Dalai, Carine Ho, Timothy A. Blauwkamp, Cynthia E. Fisher, Desiree Hollemon, Jacob Keane-Candib
Publikováno v:
Clin Infect Dis
Background Noninvasive diagnostic options are limited for invasive mold infections (IMIs). We evaluated the performance of a plasma microbial cell-free DNA sequencing (mcfDNA-Seq) test for diagnosing pulmonary IMI after hematopoietic cell transplant
Autor:
Radha Duttagupta, David K. Hong, Timothy A. Blauwkamp, Desiree Hollemon, Alex Hirst, Ann T MacIntyre
Publikováno v:
Applied Health Economics and Health Policy
Background Invasive fungal infection is a major source of morbidity and mortality. The usage of microbial cell-free DNA for the detection and identification of invasive fungal infection has been considered as a potential alternative to invasive proce
Autor:
Galit Meshulam-Simon, David K. Hong, Michael Rosen, Sanjeev Balakrishnan, Gregory D. Wall, Igor D. Vilfan, Fred Christians, Samuel Yang, Judith C. Wilber, James V. Quinn, Shivkumar Venkatasubrahmanyam, Desiree Hollemon, Lily Blair, Mickey Kertesz, Timothy A. Blauwkamp, Trupti Kawli, Martin S. Lindner, Simone A. Thair, Huijse Liza, Marla Lay Vaughn, Anita Cheung, Zoë N. Rogers, Sivan Bercovici
Publikováno v:
Nature Microbiology. 4:663-674
Thousands of pathogens are known to infect humans, but only a fraction are readily identifiable using current diagnostic methods. Microbial cell-free DNA sequencing offers the potential to non-invasively identify a wide range of infections throughout
Wnt-mediated repression via bipartite DNA recognition by TCF in the Drosophila hematopoietic system.
Publikováno v:
PLoS Genetics, Vol 10, Iss 8, p e1004509 (2014)
The Wnt/β-catenin signaling pathway plays many important roles in animal development, tissue homeostasis and human disease. Transcription factors of the TCF family mediate many Wnt transcriptional responses, promoting signal-dependent activation or
Externí odkaz:
https://doaj.org/article/bc1dd86f8f75440faeaf3c0ab0da682c
Autor:
Rajiv C McCoy, Ryan W Taylor, Timothy A Blauwkamp, Joanna L Kelley, Michael Kertesz, Dmitry Pushkarev, Dmitri A Petrov, Anna-Sophie Fiston-Lavier
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106689 (2014)
High-throughput DNA sequencing technologies have revolutionized genomic analysis, including the de novo assembly of whole genomes. Nevertheless, assembly of complex genomes remains challenging, in part due to the presence of dispersed repeats which i
Externí odkaz:
https://doaj.org/article/60b7e445792649059bef60f83c66d9fd
Autor:
Asim A. Ahmed, Felicia Ruffin, Erick R Scott, Batu K. Sharma-Kuinkel, Desiree H Hollemon, Hon Seng, Nicholas R. Degner, Lily Blair, Lisa Wanda, Lawrence P. Park, Carine Ho, Emily M. Eichenberger, Pratik Shah, Vance G. Fowler, David S. Hong, Timothy A. Blauwkamp, Christiaan R de Vries
Publikováno v:
Clin Infect Dis
Background Microbial cell-free DNA (mcfDNA) sequencing of plasma can identify the presence of a pathogen in a host. In this study, we evaluated the duration of pathogen detection by mcfDNA sequencing vs conventional blood culture in patients with bac
Autor:
Steven Coutre, Simona Zompi, David K. Hong, Paul L. Bollyky, Lily Blair, Kiran Gajurel, Bruno C. Medeiros, Jill N. Anderson, Romielle Aquino, Esther Benamu, Hon Seng, Carlos A. Gomez, Stan Deresinski, Mickey Kertesz, Timothy A. Blauwkamp, Tullia Lieb, Desiree Hollemon, Jose G. Montoya
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol 74, iss 9
Background Standard testing fails to identify a pathogen in most patients with febrile neutropenia (FN). We evaluated the ability of the Karius microbial cell-free DNA sequencing test (KT) to identify infectious etiologies of FN and its impact on ant
Autor:
Ann T, MacIntyre, Alex, Hirst, Radha, Duttagupta, Desiree, Hollemon, David K, Hong, Timothy A, Blauwkamp
Publikováno v:
Applied health economics and health policy. 19(2)
Invasive fungal infection is a major source of morbidity and mortality. The usage of microbial cell-free DNA for the detection and identification of invasive fungal infection has been considered as a potential alternative to invasive procedures allow
Autor:
Timothy J. Lepore, Carine Ho, Nitin Damle, Nira R. Pollock, Desiree Hollemon, Lily Blair, John A. Branda, Sivan Bercovici, Jacob E. Lemieux, Timothy A. Blauwkamp, Klemen Strle, Asim A. Ahmed, David K. Hong
Publikováno v:
Clin Infect Dis
Background Laboratory confirmation of early Lyme borreliosis (LB) is challenging. Serology is insensitive during the first days to weeks of infection, and blood polymerase chain reaction (PCR) offers similarly poor performance. Here, we demonstrate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e40ac30903ced16ca93af70b3f2616b
https://europepmc.org/articles/PMC8492203/
https://europepmc.org/articles/PMC8492203/