Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Timothy A. Abbott"'
Autor:
Leiping Zeng, Yanxia Liu, Xammy Huu Nguyenla, Timothy R. Abbott, Mengting Han, Yanyu Zhu, Augustine Chemparathy, Xueqiu Lin, Xinyi Chen, Haifeng Wang, Draven A. Rane, Jordan M. Spatz, Saket Jain, Arjun Rustagi, Benjamin Pinsky, Adrianna E. Zepeda, Anastasia P. Kadina, John A. Walker, Kevin Holden, Nigel Temperton, Jennifer R. Cochran, Annelise E. Barron, Michael D. Connolly, Catherine A. Blish, David B. Lewis, Sarah A. Stanley, Marie F. La Russa, Lei S. Qi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
A major challenge in coronavirus vaccination and treatment is to counteract rapid viral evolution and mutations. Here the authors show that CRISPR-Cas13d can be used as a broad-spectrum antiviral to inhibit human coronaviruses, including new SARS-CoV
Externí odkaz:
https://doaj.org/article/b19524c1f85b4105af7741efdca8ff41
Autor:
Muneaki Nakamura, Prashanth Srinivasan, Michael Chavez, Matthew A. Carter, Antonia A. Dominguez, Marie La Russa, Matthew B. Lau, Timothy R. Abbott, Xiaoshu Xu, Dehua Zhao, Yuchen Gao, Nathan H. Kipniss, Christina D. Smolke, Joseph Bondy-Denomy, Lei S. Qi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Anti-CRISPR proteins derived from phage can abrogate CRISPR activity. The authors repurpose these molecules for demonstrating genomic write-protection and pre-programmed gene expression circuits.
Externí odkaz:
https://doaj.org/article/4ee1c4c14f3b4f9ea9f6a31062906453
Autor:
Nathan H. Kipniss, P. C. Dave P. Dingal, Timothy R. Abbott, Yuchen Gao, Haifeng Wang, Antonia A. Dominguez, Louai Labanieh, Lei S. Qi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
G-protein-coupled receptors are a large and diverse group of eukaryotic membrane receptors. Here the authors couple GPCRs to dCas9 to link extracellular sensing to genome regulation.
Externí odkaz:
https://doaj.org/article/e70108db447c4b069358555aee209a1d
Autor:
Steven P. Brady, Debora Goedert, Lauren E. Frymus, Francisco Javier Zamora‐Camacho, Peter C. Smith, Caroline J. Zeiss, Mar Comas, Timothy A. Abbott, Silvia P. Basu, Jason C. DeAndressi, Mia E. Forgione, Michael J. Maloney, Joseph L. Priester, Faruk Senturk, Richard V. Szeligowski, Alina S. Tucker, Mason Zhang, Ryan Calsbeek
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Human activities have caused massive losses of natural populations across the globe. Like many groups, amphibians have experienced substantial declines worldwide, driven by environmental changes such as habitat conversion, pollution, and disease emer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::314d5289bc71ae487783f07dd14cca6c
https://doi.org/10.1111/fwb.13907
https://doi.org/10.1111/fwb.13907
Autor:
Matthew A. Carter, Christina D. Smolke, Antonia A. Dominguez, Joseph Bondy-Denomy, Yuchen Gao, Prashanth Srinivasan, Muneaki Nakamura, Nathan H. Kipniss, Timothy R. Abbott, Marie La Russa, Dehua Zhao, Xiaoshu Xu, Matthew B. Lau, Michael Chavez, Lei S. Qi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Nature communications, vol 10, iss 1
Nature Communications
Nature communications, vol 10, iss 1
Repurposed CRISPR-Cas molecules provide a useful tool set for broad applications of genomic editing and regulation of gene expression in prokaryotes and eukaryotes. Recent discovery of phage-derived proteins, anti-CRISPRs, which serve to abrogate nat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02dc8a15e81cbfb32874205221a4ef8b
https://doaj.org/article/4ee1c4c14f3b4f9ea9f6a31062906453
https://doaj.org/article/4ee1c4c14f3b4f9ea9f6a31062906453
Autor:
Nicholas S. Heaton, Robert J. Debs, Girija Dhamdhere, Leiping Zeng, Drew Endy, Tara Pande, Marie La Russa, David B. Lewis, Lei S. Qi, Laine E. Goudy, Augustine Chemparathy, Yanxia Liu, Stephen Chmura, Timothy R. Abbott, Xueqiu Lin
The outbreak of the coronavirus disease 2019 (COVID-19), caused by the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), has infected more than 100,000 people worldwide with over 3,000 deaths since December 2019. There is no cure for COVI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d72f63d2187eb900abad2055862ecf
Autor:
Laine E. Goudy, Girija Dhamdhere, Stephen Chmura, Timothy R. Abbott, Lei S. Qi, Drew Endy, Marie La Russa, Augustine Chemparathy, Nicholas S. Heaton, Yanxia Liu, Xueqiu Lin, Robert J. Debs, David B. Lewis, Leiping Zeng, Tara Pande
Publikováno v:
Cell
The coronavirus disease 2019 (COVID-19) pandemic, caused by the SARS-CoV-2 virus, has highlighted the need for antiviral approaches that can target emerging viruses with no effective vaccines or pharmaceuticals. Here, we demonstrate a CRISPR-Cas13-ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c57c6c4ae47a161b4a91c2e3b76c4db
https://pubmed.ncbi.nlm.nih.gov/33560913
https://pubmed.ncbi.nlm.nih.gov/33560913
Autor:
Lei S. Qi, Marie La Russa, Muneaki Nakamura, Cindy M. Nguyen, Timothy Daley, Cordelia Yu, Albert C. Lo, Haifeng Wang, Kaiwen Luo, Yanxia Liu, Dehua Zhao, Timothy R. Abbott
Publikováno v:
Science (New York, N.Y.). 365(6459)
Tracking nucleic acids in living cells Fluorescence in situ hybridization (FISH) is a powerful molecular technique for detecting nucleic acids in cells. However, it requires cell fixation and denaturation. Wang et al. found that CRISPR-Cas9 protects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dc6c8959a00153a7b3a8cfe872ea9ee
https://pubmed.ncbi.nlm.nih.gov/31488703
https://pubmed.ncbi.nlm.nih.gov/31488703
Autor:
Kyle E. Watters, Melissa K. Takahashi, Paul M. Gasper, Alan A. Chen, Julius B. Lucks, Timothy R. Abbott, Paul D. Carlson
Publikováno v:
Cold Spring Harbor Laboratory Press
Antisense RNA-mediated transcriptional regulators are powerful tools for controlling gene expression and creating synthetic gene networks. RNA transcriptional repressors derived from natural mechanisms called attenuators are particularly versatile, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::999a969c77339f1a7c9ccca1124c1b28
https://doi.org/10.1261/rna.054916.115
https://doi.org/10.1261/rna.054916.115
Autor:
Timothy M.C. Abbott, Peter Jenniskens, Mohammad Odeh, Nicholas Moskovitz, Carl Johannink, Esko Lyytinen
Publikováno v:
Planetary and Space Science. 181:104829
The CAMS BeNeLux and UAE Astronomical Camera Network meteor shower surveys detected a FWHM = 1.8-h wide outburst of 15-Bootids on April 21/22, 2019. Both networks had clear skies throughout the night, but only between 21h28m and 00h13m UTC were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eaef6904b5f7354228318aa9c5a6f9a3
https://doi.org/10.1016/j.pss.2019.104829
https://doi.org/10.1016/j.pss.2019.104829