Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Timothy A, Hacker"'
Autor:
Ching Ying Huang, Martin W. Nicholson, Jyun Yuan Wang, Chien Yu Ting, Ming Heng Tsai, Yu Che Cheng, Chun Lin Liu, Darien Z.H. Chan, Yi Chan Lee, Ching Chuan Hsu, Yu Hung Hsu, Chiou Fong Yang, Cindy M.C. Chang, Shu Chian Ruan, Po Ju Lin, Jen Hao Lin, Li Lun Chen, Marvin L. Hsieh, Yuan Yuan Cheng, Wan Tseng Hsu, Yi Ling Lin, Chien Hsiun Chen, Yu Hsiang Hsu, Ying Ta Wu, Timothy A. Hacker, Joseph C. Wu, Timothy J. Kamp, Patrick C.H. Hsieh
Publikováno v:
Cell Reports, Vol 43, Iss 9, Pp 114748- (2024)
Externí odkaz:
https://doaj.org/article/9ae5935c5e08433db79b9871e1e395fe
Autor:
Hung-Chih Chen, Yen-Wen Liu, Kuan-Cheng Chang, Yen-Wen Wu, Yi-Ming Chen, Yu-Kai Chao, Min-Yi You, David J. Lundy, Chen-Ju Lin, Marvin L. Hsieh, Yu-Che Cheng, Ray P. Prajnamitra, Po-Ju Lin, Shu-Chian Ruan, David Hsin-Kuang Chen, Edward S. C. Shih, Ke-Wei Chen, Shih-Sheng Chang, Cindy M. C. Chang, Riley Puntney, Amy Wu Moy, Yuan-Yuan Cheng, Hsin-Yuan Chien, Jia-Jung Lee, Deng-Chyang Wu, Ming-Jing Hwang, Jennifer Coonen, Timothy A. Hacker, C-L. Eric Yen, Federico E. Rey, Timothy J. Kamp, Patrick C. H. Hsieh
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The gut microbiome and its metabolites are increasingly implicated in several cardiovascular diseases, but their role in human myocardial infarction (MI) injury responses have yet to be established. To address this, we examined stool samples
Externí odkaz:
https://doaj.org/article/6361bc3495944b3fb58bc006af3e56af
Autor:
Jun Li, Corey Carlos, Hao Zhou, Jiajie Sui, Yikai Wang, Zulmari Silva-Pedraza, Fan Yang, Yutao Dong, Ziyi Zhang, Timothy A. Hacker, Bo Liu, Yanchao Mao, Xudong Wang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Stretchability is an essential property for wearable devices to match varying strains when interfacing with soft tissues or organs. While piezoelectricity has broad application potentials as tactile sensors, artificial skins, or nanogenerato
Externí odkaz:
https://doaj.org/article/1c9122a11a0a431d86c6673bf6f85ea9
Autor:
Yanghai Zhang, Zachery R. Gregorich, Yujuan Wang, Camila Urbano Braz, Jibin Zhang, Yang Liu, Peiheng Liu, Jiaxi Shen, Nanyumuzi Aori, Timothy A. Hacker, Henk Granzier, Wei Guo
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
Human patients carrying genetic mutations in RNA binding motif 20 (RBM20) develop a clinically aggressive dilated cardiomyopathy (DCM). Genetic mutation knockin (KI) animal models imply that altered function of the arginine-serine-rich (RS) domain is
Externí odkaz:
https://doaj.org/article/64c14405f01b43cf841138c800152afd
Autor:
Rashid Al Mukaddim, Ashley M. Weichmann, Rachel Taylor, Timothy A. Hacker, Thomas Pier, Joseph Hardin, Melissa Graham, Carol C. Mitchell, Tomy Varghese
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract An adaptive Bayesian regularized cardiac strain imaging (ABR-CSI) algorithm for in vivo murine myocardial function assessment is presented. We report on 31 BALB/CJ mice (n = 17 females, n = 14 males), randomly stratified into three surgical
Externí odkaz:
https://doaj.org/article/8ea48587bea14d1f981c9ec3af5fe954
Autor:
Sarah K. El-Meanawy, Holly Dooge, Allison C. Wexler, Anna C. Kosmach, Lara Serban, Elizabeth A. Santos, Francisco J. Alvarado, Timothy A. Hacker, Mohun Ramratnam
Publikováno v:
Life, Vol 13, Iss 4, p 1015 (2023)
The mitochondrial splice variant of the sulfonylurea receptor (SUR2A-55) is associated with protection from myocardial ischemia-reperfusion (IR) injury, increased mitochondrial ATP sensitive K+ channel activity (mitoKATP) and altered glucose metaboli
Externí odkaz:
https://doaj.org/article/376756e59ec54dc4834c96253f9618b6
Autor:
Ching Ying Huang, Martin W. Nicholson, Jyun Yuan Wang, Chien Yu Ting, Ming Heng Tsai, Yu Che Cheng, Chun Lin Liu, Darien Z.H. Chan, Yi Chan Lee, Ching Chuan Hsu, Yu Hung Hsu, Chiou Fong Yang, Cindy M.C. Chang, Shu Chian Ruan, Po Ju Lin, Jen Hao Lin, Li Lun Chen, Marvin L. Hsieh, Yuan Yuan Cheng, Wan Tseng Hsu, Yi Ling Lin, Chien Hsiun Chen, Yu Hsiang Hsu, Ying Ta Wu, Timothy A. Hacker, Joseph C. Wu, Timothy J. Kamp, Patrick C.H. Hsieh
Publikováno v:
Cell Reports, Vol 39, Iss 1, Pp 110643- (2022)
Summary: In this study, we establish a population-based human induced pluripotent stem cell (hiPSC) drug screening platform for toxicity assessment. After recruiting 1,000 healthy donors and screening for high-frequency human leukocyte antigen (HLA)
Externí odkaz:
https://doaj.org/article/da8bc8cb1a58446e870b6a5639aa6740
Autor:
Chen-Yun Chen, Oi Kuan Choong, Li-Wei Liu, Yu-Che Cheng, Sung-Chou Li, Christopher Y.T. Yen, Menq-Rong Wu, Ming-Hsien Chiang, Tien-Jui Tsang, Yen-Wen Wu, Lung-Chun Lin, Yuh-Lien Chen, Wen-Chang Lin, Timothy A. Hacker, Timothy J. Kamp, Patrick C.H. Hsieh
Publikováno v:
EBioMedicine, Vol 46, Iss , Pp 236-247 (2019)
Background: Myocardial infarction (MI) is a life-threatening disease, often leading to heart failure. Defining therapeutic targets at an early time point is important to prevent heart failure. Methods: MicroRNA screening was performed at early time p
Externí odkaz:
https://doaj.org/article/fe3e0dca7c07482cbec6efdcec0bc8a7
Autor:
Yogananda S. Markandeya, Zachery R. Gregorich, Li Feng, Vignesh Ramchandran, Thomas O' Hara, Ravi Vaidyanathan, Catherine Mansfield, Alexis M. Keefe, Carl J. Beglinger, Jabe M. Best, Matthew M. Kalscheur, Martin R. Lea, Timothy A. Hacker, Julia Gorelik, Natalia A. Trayanova, Lee L. Eckhardt, Jonathan C. Makielski, Ravi C. Balijepalli, Timothy J. Kamp
Publikováno v:
Journal of Molecular and Cellular Cardiology. 177:38-49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2eb152118a1a2203da32cab991cb2de6
https://doi.org/10.1016/j.yjmcc.2023.02.005
https://doi.org/10.1016/j.yjmcc.2023.02.005
Autor:
Martin W. Nicholson, Ching-Ying Huang, Jyun-Yuan Wang, Chien-Yu Ting, Yu-Che Cheng, Darien Z. H. Chan, Yi-Chan Lee, Ching-Chuan Hsu, Yu-Hung Hsu, Cindy M. C. Chang, Marvin L. Hsieh, Yuan-Yuan Cheng, Yi-Ling Lin, Chien-Hsiun Chen, Ying-Ta Wu, Timothy A. Hacker, Joseph C. Wu, Timothy J. Kamp, Patrick C. H. Hsieh
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 765 (2022)
Since December 2019, the novel coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected ~435 million people and caused ~6 million related deaths as of March 2022. To combat COVID-19, th
Externí odkaz:
https://doaj.org/article/281becb748f34355a75c8da991a28a2e