Zobrazeno 1 - 10
of 260
pro vyhledávání: '"Timothy, Noël"'
Autor:
Daniele Mazzarella, Jelena Stanić, Miguel Bernús, Arad Seyed Mehdi, Cassandra J. Henderson, Omar Boutureira, Timothy Noël
Publikováno v:
JACS Au, Vol 4, Iss 8, Pp 2989-2994 (2024)
Externí odkaz:
https://doaj.org/article/a149304f55a14506862684ed52a33450
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-7 (2024)
Abstract Sulfur-containing scaffolds originating from small alkyl fragments play a crucial role in various pharmaceuticals, agrochemicals, and materials. Nonetheless, their synthesis using conventional methods presents significant challenges. In this
Externí odkaz:
https://doaj.org/article/7c7c300790f54addaafa87f262f33001
Autor:
Ting Wan, Luca Capaldo, Jonas Djossou, Angela Staffa, Felix J. de Zwart, Bas de Bruin, Timothy Noël
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract In recent years, there has been a growing demand for drug design approaches that incorporate a higher number of sp3-hybridized carbons, necessitating the development of innovative cross-coupling strategies to reliably introduce aliphatic fra
Externí odkaz:
https://doaj.org/article/01069581bf4d4b2c95acac4ac0e36a1d
Autor:
Stefano Bonciolini, Antonio Pulcinella, Matteo Leone, Debora Schiroli, Adrián Luguera Ruiz, Andrea Sorato, Maryne A. J. Dubois, Ranganath Gopalakrishnan, Geraldine Masson, Nicola Della Ca’, Stefano Protti, Maurizio Fagnoni, Eli Zysman-Colman, Magnus Johansson, Timothy Noël
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract In contemporary drug discovery, enhancing the sp3-hybridized character of molecular structures is paramount, necessitating innovative synthetic methods. Herein, we introduce a deoxygenative cross-electrophile coupling technique that pairs ea
Externí odkaz:
https://doaj.org/article/f268aa4aece843bb96f8b5b86625428c
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Decatungstate-enabled Hydrogen Atom Transfer (HAT) photocatalysis of hydrocarbon scaffolds enabled rapid access to new C(sp3)-enriched chemical space. Here, the authors present in-line TBADT recovery with organic solvent nanofiltration (OSN) as an an
Externí odkaz:
https://doaj.org/article/1fa433346d0247e4a29fdfaff1625c72
Autor:
Ting Wan, Zhenghui Wen, Gabriele Laudadio, Luca Capaldo, Rob Lammers, Juan A. Rincón, Pablo García-Losada, Carlos Mateos, Michael O. Frederick, Rémy Broersma, Timothy Noël
Publikováno v:
ACS Central Science, Vol 8, Iss 1, Pp 51-56 (2021)
Externí odkaz:
https://doaj.org/article/f0b40780e1294bb7831c474c3489dcab
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
The identification of true catalytically active species allows for a better understanding of a catalytic process and its potential improvement. Here, the authors report that the perceived heterogeneous photocatalysis with Bi2O3 in the presence of alk
Externí odkaz:
https://doaj.org/article/9cd2a2871a1f4a668597cd968a516b7a
Autor:
Alexander V. Nyuchev, Ting Wan, Borja Cendón, Carlo Sambiagio, Job J. C. Struijs, Michelle Ho, Moisés Gulías, Ying Wang, Timothy Noël
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 1305-1312 (2020)
The first example of photocatalytic trifluoromethoxylation of arenes and heteroarenes under continuous-flow conditions is described. Application of continuous-flow microreactor technology allowed to reduce the residence time up to 16 times in compari
Externí odkaz:
https://doaj.org/article/695bdaecba9c43be82a1b379fe4cd786
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 809-817 (2020)
A ruthenium-catalyzed photoredox coupling of substituted N-aryltetrahydroisoquinolines (THIQs) and different bench-stable pyridinium salts was successfully developed to give fast access to 1-benzyl-THIQs. Furthermore, secondary alkyl and allyl groups
Externí odkaz:
https://doaj.org/article/75d088305d19408caca332446314c71e
Autor:
Morten M. C. H. van Schie, Tiago Pedroso de Almeida, Gabriele Laudadio, Florian Tieves, Elena Fernández-Fueyo, Timothy Noël, Isabel W. C. E. Arends, Frank Hollmann
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 14, Iss 1, Pp 697-703 (2018)
The biocatalytic preparation of trans-hex-2-enal from trans-hex-2-enol using a novel aryl alcohol oxidase from Pleurotus eryngii (PeAAOx) is reported. As O2-dependent enzyme PeAAOx-dependent reactions are generally plagued by the poor solubility of O
Externí odkaz:
https://doaj.org/article/b3814f3159734c9c84ee473557d71d03