Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Timothée Lionnet"'
Autor:
Alon Kalo, Itamar Kanter, Amit Shraga, Jonathan Sheinberger, Hadar Tzemach, Noa Kinor, Robert H. Singer, Timothée Lionnet, Yaron Shav-Tal
Publikováno v:
Cell Reports, Vol 11, Iss 3, Pp 419-432 (2015)
The transcriptional response of β-actin to extra-cellular stimuli is a paradigm for transcription factor complex assembly and regulation. Serum induction leads to a precisely timed pulse of β-actin transcription in the cell population. Actin protei
Externí odkaz:
https://doaj.org/article/1bbd4d4d9d534e809ada382ad6b88c81
Autor:
Won-Ki Cho, Namrata Jayanth, Brian P English, Takuma Inoue, J Owen Andrews, William Conway, Jonathan B Grimm, Jan-Hendrik Spille, Luke D Lavis, Timothée Lionnet, Ibrahim I Cisse
Publikováno v:
eLife, Vol 5 (2016)
Protein clustering is a hallmark of genome regulation in mammalian cells. However, the dynamic molecular processes involved make it difficult to correlate clustering with functional consequences in vivo. We developed a live-cell super-resolution appr
Externí odkaz:
https://doaj.org/article/492d9368f0144434aab5205106f266e9
Autor:
Zachary B Katz, Brian P English, Timothée Lionnet, Young J Yoon, Nilah Monnier, Ben Ovryn, Mark Bathe, Robert H Singer
Publikováno v:
eLife, Vol 5 (2016)
Messenger RNA localization is important for cell motility by local protein translation. However, while single mRNAs can be imaged and their movements tracked in single cells, it has not yet been possible to determine whether these mRNAs are actively
Externí odkaz:
https://doaj.org/article/46e36cf08f3d447aaa02922fcc3821f4
Autor:
Yi-ying Chou, Nicholas S. Heaton, Qinshan Gao, Peter Palese, Robert H. Singer, Timothée Lionnet
Publikováno v:
PLoS Pathogens, Vol 9, Iss 7 (2013)
Externí odkaz:
https://doaj.org/article/0c370b4b8b464f78ab2e374bb3879246
Autor:
Yi-ying Chou, Nicholas S Heaton, Qinshan Gao, Peter Palese, Robert H Singer, Timothée Lionnet
Publikováno v:
PLoS Pathogens, Vol 9, Iss 5, p e1003358 (2013)
The Influenza A virus genome consists of eight negative sense, single-stranded RNA segments. Although it has been established that most virus particles contain a single copy of each of the eight viral RNAs, the packaging selection mechanism remains p
Externí odkaz:
https://doaj.org/article/149978ab166748f8804a936920f5f9cd
Autor:
Timothée Lionnet
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp 1-2 (2013)
Externí odkaz:
https://doaj.org/article/a53712b8b9654890994d51cdf4843e00
Autor:
Sudarshan Pinglay, Milica Bulajić, Dylan P. Rahe, Emily Huang, Ran Brosh, Nicholas E. Mamrak, Benjamin R. King, Sergei German, John A. Cadley, Lila Rieber, Nicole Easo, Timothée Lionnet, Shaun Mahony, Matthew T. Maurano, Liam J. Holt, Esteban O. Mazzoni, Jef D. Boeke
Publikováno v:
Science
INTRODUCTION: Despite an ever-expanding catalog of noncoding elements that are implicated in the control of mammalian gene expression, how the regulatory input from multiple elements is integrated across a genomic neighborhood has remained largely un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7772d22daf61c45f770cf5e49e7233
https://doi.org/10.1126/science.abk2820
https://doi.org/10.1126/science.abk2820
Autor:
Nicholas E Mamrak, Nader Alerasool, Daniel Griffith, Alex S Holehouse, Mikko Taipale, Timothée Lionnet
Cell-to-cell variability is shaped by transcription dynamics because genes are transcribed in bursts interspersed with inactive periods. The stochasticity of bursting means that genes transcribed in rare bursts exhibit more heterogeneity at the singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec105ea0409f5a075626843d82287701
https://doi.org/10.1101/2022.06.01.494187
https://doi.org/10.1101/2022.06.01.494187
Autor:
Timothée Lionnet, Carl Wu
Publikováno v:
Curr Opin Genet Dev
A universe of transcription factors (TFs), cofactors, as well as chromatin remodeling and modifying enzymes combine or compete on chromatin to control transcription. Measuring quantitatively how these proteins dynamically interact is required in orde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9f9f6f03a4104189b1535c2a7d70d4a
https://doi.org/10.1016/j.gde.2020.12.001
https://doi.org/10.1016/j.gde.2020.12.001
Autor:
Sonali Narang, Yohana Ghebrechristos, Nikki A. Evensen, Nina Murrell, Sylwia Jasinski, Talia H. Ostrow, David T. Teachey, Elizabeth A. Raetz, Timothee Lionnet, Matthew Witkowski, Iannis Aifantis, Aristotelis Tsirigos, William L. Carroll
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Relapsed pediatric B-cell acute lymphoblastic leukemia (B-ALL) remains one of the leading causes of cancer mortality in children. We performed Hi-C, ATAC-seq, and RNA-seq on 12 matched diagnosis/relapse pediatric leukemia specimens to uncove
Externí odkaz:
https://doaj.org/article/fb1e74a501a7414f905b010548c71afa