Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Timothée, Revil"'
Autor:
Wejdan M. Alenezi, Caitlin T. Fierheller, Corinne Serruya, Timothée Revil, Kathleen K. Oros, Deepak N. Subramanian, Jeffrey Bruce, Dan Spiegelman, Trevor Pugh, Ian G. Campbell, Anne-Marie Mes-Masson, Diane Provencher, William D. Foulkes, Zaki El Haffaf, Guy Rouleau, Luigi Bouchard, Celia M. T. Greenwood, Jiannis Ragoussis, Patricia N. Tonin
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Not all familial ovarian cancer (OC) cases are explained by pathogenic germline variants in known risk genes. A candidate gene approach involving DNA repair pathway genes was applied to identify rare recurring pathogenic variants in familial OC cases
Externí odkaz:
https://doaj.org/article/05d239ab593d4e42b75d51380a913fb1
Autor:
Caitlin T. Fierheller, Laure Guitton-Sert, Wejdan M. Alenezi, Timothée Revil, Kathleen K. Oros, Yuandi Gao, Karine Bedard, Suzanna L. Arcand, Corinne Serruya, Supriya Behl, Liliane Meunier, Hubert Fleury, Eleanor Fewings, Deepak N. Subramanian, Javad Nadaf, Jeffrey P. Bruce, Rachel Bell, Diane Provencher, William D. Foulkes, Zaki El Haffaf, Anne-Marie Mes-Masson, Jacek Majewski, Trevor J. Pugh, Marc Tischkowitz, Paul A. James, Ian G. Campbell, Celia M. T. Greenwood, Jiannis Ragoussis, Jean-Yves Masson, Patricia N. Tonin
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-26 (2021)
Abstract Background Familial ovarian cancer (OC) cases not harbouring pathogenic variants in either of the BRCA1 and BRCA2 OC-predisposing genes, which function in homologous recombination (HR) of DNA, could involve pathogenic variants in other DNA r
Externí odkaz:
https://doaj.org/article/52b67832911d434ca9c1266c56a3622d
Autor:
Paul Savage, Alexis Blanchet-Cohen, Timothée Revil, Dunarel Badescu, Sadiq M.I. Saleh, Yu-Chang Wang, Dongmei Zuo, Leah Liu, Nicholas R. Bertos, Valentina Munoz-Ramos, Mark Basik, Kevin Petrecca, Jamil Asselah, Sarkis Meterissian, Marie-Christine Guiot, Atilla Omeroglu, Claudia L. Kleinman, Morag Park, Jiannis Ragoussis
Publikováno v:
Cell Reports, Vol 21, Iss 5, Pp 1140-1149 (2017)
Summary: Therapies targeting epidermal growth factor receptor (EGFR) have variable and unpredictable responses in breast cancer. Screening triple-negative breast cancer (TNBC) patient-derived xenografts (PDXs), we identify a subset responsive to EGFR
Externí odkaz:
https://doaj.org/article/32915cd9ec2440a18a2d27b0b6c96083
Autor:
Caitlin T. Fierheller, Wejdan M. Alenezi, Corinne Serruya, Timothée Revil, Setor Amuzu, Karine Bedard, Deepak N. Subramanian, Eleanor Fewings, Jeffrey P. Bruce, Stephenie Prokopec, Luigi Bouchard, Diane Provencher, William D. Foulkes, Zaki El Haffaf, Anne-Marie Mes-Masson, Marc Tischkowitz, Ian G. Campbell, Trevor J. Pugh, Celia M. T. Greenwood, Jiannis Ragoussis, Patricia N. Tonin
Publikováno v:
Genes
Volume 14
Issue 2
Pages: 277
Volume 14
Issue 2
Pages: 277
Peer reviewed: True
Funder: Scholarship Award from The Ministry of Education, Saudi Arabia
Funder: FRQS and Quebec Breast Cancer Foundation
Funder: Fonds de recherche du Québec, McGill University
FANCI was recently identified as
Funder: Scholarship Award from The Ministry of Education, Saudi Arabia
Funder: FRQS and Quebec Breast Cancer Foundation
Funder: Fonds de recherche du Québec, McGill University
FANCI was recently identified as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cbfe1acca1f983a195b7640016f9ddd
https://www.repository.cam.ac.uk/handle/1810/348050
https://www.repository.cam.ac.uk/handle/1810/348050
Autor:
Wejdan M. Alenezi, Caitlin T. Fierheller, Timothée Revil, Corinne Serruya, Anne-Marie Mes-Masson, William D. Foulkes, Diane Provencher, Zaki El Haffaf, Jiannis Ragoussis, Patricia N. Tonin
Publikováno v:
Genes; Volume 13; Issue 4; Pages: 697
Background: Detecting pathogenic intronic variants resulting in aberrant splicing remains a challenge in routine genetic testing. We describe germline whole-exome sequencing (WES) analyses and apply in silico predictive tools of familial ovarian canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4122d788b98df73e1eaefa6cf1ce5c29
Autor:
Rui Manuel Reis, Henrique de Campos Reis Galvão, Rodrigo Augusto Depieri Michelli, Cristiano de Pádua Souza, Jiannis Ragoussis, Giovana Tardin Torrezan, Natalia Campacci, Timothée Revil, Fergus J. Couch, Patricia N. Tonin, Cristina da Silva Sabato, Bruna D. F. Barros, André Escremim de Paula, Rebeca Silveira Grasel, Carlos Eduardo Mattos da Cunha Andrade, Marcus Matsushita, Gabriela C Fernandes, Matias Eliseo Melendez, Paula Silva Felicio, Edenir Inêz Palmero, Steven N. Hart, Dirce Maria Carraro
Publikováno v:
Human Mutation
The current study aimed to identify new breast and/or ovarian cancer predisposition genes. For that, whole‐exome sequencing (WES) was performed in the germline DNA of 52 non‐BRCA1/BRCA2/TP53 mutation carrier women at high‐risk for hereditary br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bdc4649601948f2a371373f0cf4fee5
https://doi.org/10.1002/humu.24158
https://doi.org/10.1002/humu.24158
Autor:
Wejdan M, Alenezi, Larissa, Milano, Caitlin T, Fierheller, Corinne, Serruya, Timothée, Revil, Kathleen K, Oros, Supriya, Behl, Suzanna L, Arcand, Porangana, Nayar, Dan, Spiegelman, Simon, Gravel, Anne-Marie, Mes-Masson, Diane, Provencher, William D, Foulkes, Zaki, El Haffaf, Guy, Rouleau, Luigi, Bouchard, Celia M T, Greenwood, Jean-Yves, Masson, Jiannis, Ragoussis, Patricia N, Tonin
Publikováno v:
Cancers. 14(9)
To identify candidate variants in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::07523a68786c2fb798b70a343bad4cac
https://pubmed.ncbi.nlm.nih.gov/35565380
https://pubmed.ncbi.nlm.nih.gov/35565380
Autor:
Deepak N Subramanian, Patricia N. Tonin, Jean-Yves Masson, Jeff Bruce, Kathleen Klein Oros, Jacek Majewski, Celia M. T. Greenwood, Hubert Fleury, Paul A. James, Jiannis Ragoussis, Anne-Marie Mes-Masson, Yuandi Gao, Karine Bédard, Ian G. Campbell, Supriya Behl, Wejdan M Alenezi, Javad Nadaf, Eleanor Fewings, Timothée Revil, Zaki El Haffaf, Trevor J. Pugh, Marc Tischkowitz, Diane Provencher, Laure Guitton-Sert, Caitlin T Fierheller, Corinne Serruya, Liliane Meunier, William D. Foulkes, Suzanna L. Arcand, Rachel Bell
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-26 (2021)
Genome Medicine
Genome Medicine
Background Familial ovarian cancer (OC) cases not harbouring pathogenic variants in either of the BRCA1 and BRCA2 OC-predisposing genes, which function in homologous recombination (HR) of DNA, could involve pathogenic variants in other DNA repair pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd6db2b43c5a42db34670458a4a0d48
https://doi.org/10.1186/s13073-021-00998-5
https://doi.org/10.1186/s13073-021-00998-5
Autor:
Anne-Marie Mes-Masson, Marc Tischkowitz, Diane Provencher, Zaki El Haffaf, Javad Nadaf, Celia M. T. Greenwood, Eleanor Fewings, Jean-Yves Masson, William D. Foulkes, Caitlin T Fierheller, Timothée Revil, Jacek Majewski, Laure Guitton-Sert, Supriya Behl, Liliane Meunier, Hubert Fleury, Deepak N Subramanian, Jiannis Ragoussis, Kathleen Klein Oros, Paul A. James, Suzanna L. Arcand, Corinne Serruya, Karine Bédard, Patricia N. Tonin, Ian G. Campbell, Wejdan M Alenezi
Some familial ovarian cancer (OC) could be due to rare risk alleles in genes that each account for a relatively small proportion of cases not due toBRCA1andBRCA2, major risk genes in the homologous recombination (HR) DNA repair pathway. We report a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebcb8f16a6b8bb756da2d1f004c938d9
https://doi.org/10.1101/2020.05.04.20090407
https://doi.org/10.1101/2020.05.04.20090407
Autor:
Anne-Marie Mes-Masson, Jean-Yves Masson, William D. Foulkes, Celia M. T. Greenwood, Zaki El Haffaf, Patricia N. Tonin, Caitlin T Fierheller, Wejdan M Alenezi, Jiannis Ragoussis, Corinne Serruya, Diane Provencher, Timothée Revil, Javad Nadaf
Publikováno v:
Cancer Research. 81:2056-2056
The potentially pathogenic variant (PPV), FANCI c.1813C>T; p.L605F, in a new candidate ovarian cancer (OC) predisposing gene was discovered by whole exome sequencing (WES) of familial OC cases from the founder French Canadian (FC) population for disc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9b7bfc8343b6826514f4349067a962a
https://doi.org/10.1158/1538-7445.am2021-2056
https://doi.org/10.1158/1538-7445.am2021-2056