Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Timothé Maujean"'
Autor:
Timothé Maujean, Sridévi M. Ramanoudjame, Stéphanie Riché, Clothilde Le Guen, Frédéric Boisson, Sylviane Muller, Dominique Bonnet, Mihaela Gulea, Patrice Marchand
Publikováno v:
Molecules, Vol 29, Iss 13, p 3198 (2024)
Radiolabeled peptides are valuable tools for diagnosis or therapies; they are often radiofluorinated using an indirect approach based on an F-18 prosthetic group. Herein, we are reporting our results on the F-18 radiolabeling of three peptides using
Externí odkaz:
https://doaj.org/article/e98bceec421c43ab89a851fb214b623c
Autor:
Timothé Maujean, Patrice Marchand, Patrick Wagner, Stéphanie Riché, Frédéric Boisson, Nicolas Girard, Julie Karpenko, Dominique Bonnet, Mihaela Gulea
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. :1-4
Autor:
Timothé Maujean, Patrice Marchand, Patrick Wagner, Stéphanie Riché, Frédéric Boisson, Nicolas Girard, Dominique Bonnet, Mihaela Gulea
Publikováno v:
Chemical Communications. 58:11151-11154
The hetero-Diels–Alder reaction involving a dithioester and a radiofluorinated diene as a novel prosthetic group was used as a catalyst-free click-reaction for the indirect 18F-labelling of peptides and applied to a PSMA-ligand for in vivo imaging.
Autor:
Timothé Maujean, Patrick Wagner, Christel Valencia, Stéphanie Riché, Xavier Iturrioz, Pascal Villa, Nicolas Girard, Julie Karpenko, Mihaela Gulea, Dominique Bonnet
Publikováno v:
Bioconjugate chemistry.
Herein, we describe a catalyst-free thia-Diels-Alder cycloaddition for the chemoselective labeling of fully deprotected phosphonodithioester-peptides in solution with fluorophores functionalized with an exocyclic diene. The reaction was optimized on
Publikováno v:
RSC Advances
RSC Advances, Royal Society of Chemistry, 2020, 10 (71), pp.43358-43370. ⟨10.1039/d0ra09457a⟩
RSC Advances, Royal Society of Chemistry, 2020, 10 (71), pp.43358-43370. ⟨10.1039/d0ra09457a⟩
International audience; Nitrogen-containing heterocycles represent a major source of pharmacological probes and drug candidates. To extend their molecular diversity and their potential biological activities, it is of importance to design and synthesi
Publikováno v:
European Journal of Organic Chemistry
European Journal of Organic Chemistry, Wiley-VCH Verlag, 2020, 2020 (47), pp.7385-7395. ⟨10.1002/ejoc.202001339⟩
European Journal of Organic Chemistry, Wiley-VCH Verlag, 2020, 2020 (47), pp.7385-7395. ⟨10.1002/ejoc.202001339⟩
International audience; Original endocyclic enamides based on a bicyclic aza-diketopiperazine (aza-DKP) structure have been used as dienophile partners in the Povarov reaction. The reported method represents a successful strategy for the structural d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7beff2aba1cf47b98ff4601fea0b7d29
https://hal.archives-ouvertes.fr/hal-03441064/document
https://hal.archives-ouvertes.fr/hal-03441064/document
Publikováno v:
Angewandte Chemie (International Ed. in English)
Angewandte Chemie International Edition
Angewandte Chemie International Edition
The power of the Cloud has been harnessed for pharmaceutical compound production with remote servers based in Tokyo, Japan being left to autonomously find optimal synthesis conditions for three active pharmaceutical ingredients (APIs) in laboratories