Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Timona S Tyllis"'
Autor:
Veronika Bandara, Jade Foeng, Batjargal Gundsambuu, Todd S. Norton, Silvana Napoli, Dylan J. McPeake, Timona S. Tyllis, Elaheh Rohani-Rad, Caitlin Abbott, Stuart J. Mills, Lih Y. Tan, Emma J. Thompson, Vasiliki M. Willet, Victoria J. Nikitaras, Jieren Zheng, Iain Comerford, Adam Johnson, Justin Coombs, Martin K. Oehler, Carmela Ricciardelli, Allison J. Cowin, Claudine S. Bonder, Michael Jensen, Timothy J. Sadlon, Shaun R. McColl, Simon C. Barry
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Chimeric antigen receptor (CAR)-T cell immunotherapy is a novel treatment that genetically modifies the patients’ own T cells to target and kill malignant cells. However, identification of tumour-specific antigens expressed on multiple sol
Externí odkaz:
https://doaj.org/article/a5287b5698b04be1aa66caa9922e1384
Autor:
Cameron R. Bastow, Ervin E. Kara, Timona S. Tyllis, Carola G. Vinuesa, Shaun R. McColl, Iain Comerford
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Follicular T cells including T follicular helper (TFH) and T follicular regulatory (TFR) cells are essential in supporting and regulating the quality of antibody responses that develop in the germinal centre (GC). Follicular T cell migration during t
Externí odkaz:
https://doaj.org/article/a0e35c22794d47cdb9314e6c4850a5b4
Autor:
Timona S. Tyllis, Kevin A. Fenix, Todd S. Norton, Ervin E. Kara, Duncan R. McKenzie, Shannon C. David, Mohammed Alsharifi, Di Yu, Shaun R. McColl, Iain Comerford
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Crosstalk between T and B cells is crucial for generating high-affinity, class-switched antibody responses. The roles of CD4+ T cells in this process have been well-characterised. In contrast, regulation of antibody responses by CD8+ T cells is signi
Externí odkaz:
https://doaj.org/article/b40752eca7c74b949e6eafad9578fed3
Autor:
Duncan R. McKenzie, Ervin E. Kara, Cameron R. Bastow, Timona S. Tyllis, Kevin A. Fenix, Carly E. Gregor, Jasmine J. Wilson, Rachelle Babb, James C. Paton, Axel Kallies, Stephen L. Nutt, Anne Brüstle, Matthias Mack, Iain Comerford, Shaun R. McColl
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
IL-17-producing γδ T (γδT17) cells position in barrier tissues but also home to inflammatory sites. How this trafficking is regulated is unclear. Here the authors show that the dynamic expression of chemokine receptors CCR2 and CCR6 differentiate
Externí odkaz:
https://doaj.org/article/7231ed3e23fa45de85a4ea9d25972b36
Autor:
Caitlin A Abbott, Emily L Freimayer, Timona S Tyllis, Todd S Norton, Mohammed Alsharifi, Aaron H S Heng, Stephen M Pederson, Zhipeng Qu, Mark Armstrong, Geoffrey R Hill, Shaun R McColl, Iain Comerford
Type I regulatory (Tr1) cells contribute to immune suppression in the context of chronic infection, autoimmunity, and transplant tolerance. However, their physiological relevance in the resolution of acute respiratory infection is not understood. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ec3da9206357722320a59534181b5f8
https://doi.org/10.1101/2022.12.06.519368
https://doi.org/10.1101/2022.12.06.519368
Autor:
Cameron R, Bastow, Ervin E, Kara, Timona S, Tyllis, Carola G, Vinuesa, Shaun R, McColl, Iain, Comerford
Publikováno v:
Frontiers in immunology. 13
Follicular T cells including T follicular helper (T
Autor:
Claudine S. Bonder, Timona S. Tyllis, Simon Barry, Shaun R. McColl, Silvana Napoli, Victoria Nikitaras, Jade Foeng, Michael C. Jensen, Veronika Bandara, Justin Taylor Coombs, Vasiliki Willet, Timothy John Sadlon, Lih Tan, Caitlin Abbott, Elaheh Rohani Rad, Allison J. Cowin, Batjargal Gundsambuu, Stuart J. Mills, Todd Norton, Carmela Ricciardelli, Adam Johnson, Martin K. Oehler, Dylan McPeake
Chimeric antigen receptor (CAR)-T immunotherapy is a novel treatment that genetically modifies the patient’s own T cells to target and kill malignant cells. CAR-T cells demonstrated robust clinical activity against certain B-cell malignancies. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68ae0739107f30e52947cdac353f8ca4
https://doi.org/10.21203/rs.3.rs-1073214/v1
https://doi.org/10.21203/rs.3.rs-1073214/v1
Autor:
Kevin A. Fenix, Shannon C. David, Di Yu, Timona S. Tyllis, Todd Norton, Duncan R. McKenzie, Ervin E. Kara, Shaun R. McColl, Iain Comerford, Mohammed Alsharifi
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
Crosstalk between T and B cells is crucial for generating high-affinity, class-switched antibody responses. The roles of CD4+T cells in this process have been well-characterised. In contrast, regulation of antibody responses by CD8+T cells is signifi
Autor:
Todd Norton, Shaun R. McColl, James C. Paton, Zoe Laan, Iain Comerford, Shannon C. David, Justin Davies, Timona S. Tyllis, Timothy R. Hirst, Jasmine J. Wilson, Mohammed Alsharifi, Eve V. Singleton
Publikováno v:
Nature Microbiology. 4:1316-1327
The upper respiratory tract is continuously exposed to a vast array of potentially pathogenic viruses and bacteria. Influenza A virus (IAV) has particular synergism with the commensal bacterium Streptococcus pneumoniae in this niche, and co-infection
Autor:
Dylan J. McPeake, Timona S. Tyllis, Jade Foeng, Veronika Bandara, Caitlin A. Abbott, Batjargal Gundsambuu, Elaheh Rohani-Rad, Silvana Napoli, Timothy Sadlon, Simon C. Barry, Shaun R. McColl
Publikováno v:
Cancer Research. 82:5574-5574
Colorectal cancer (CRC) is the third most diagnosed cancer and incidence rates are rapidly increasing among young adults. Despite current treatments, the 5-year survival rate is approximately 65%, highlighting an urgent need for new therapies. Leucin