Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Timon E. Adolph"'
Autor:
Björn Becker, Felix Wottawa, Mohamed Bakr, Eric Koncina, Lisa Mayr, Julia Kugler, Guang Yang, Samuel J. Windross, Laura Neises, Neha Mishra, Danielle Harris, Florian Tran, Lina Welz, Julian Schwärzler, Zoltán Bánki, Stephanie T. Stengel, Go Ito, Christina Krötz, Olivia I. Coleman, Christian Jaeger, Dirk Haller, Søren R. Paludan, Richard Blumberg, Arthur Kaser, Luka Cicin-Sain, Stefan Schreiber, Timon E. Adolph, Elisabeth Letellier, Philip Rosenstiel, Johannes Meiser, Konrad Aden
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109173- (2024)
Summary: Inflammatory bowel diseases are characterized by the chronic relapsing inflammation of the gastrointestinal tract. While the molecular causality between endoplasmic reticulum (ER) stress and intestinal inflammation is widely accepted, the me
Externí odkaz:
https://doaj.org/article/b82b754dd2874bbc89024fd998a49788
Autor:
Christoph Grander, Moritz Meyer, Daniel Steinacher, Thierry Claudel, Bela Hausmann, Petra Pjevac, Felix Grabherr, Georg Oberhuber, Manuel Grander, Natascha Brigo, Almina Jukic, Julian Schwärzler, Günter Weiss, Timon E. Adolph, Michael Trauner, Herbert Tilg
Publikováno v:
JHEP Reports, Vol 5, Iss 11, Pp 100872- (2023)
Background & Aims: Alcohol-related liver disease (ALD) is a global healthcare challenge with limited treatment options. 24-Norursodeoxycholic acid (NorUDCA) is a synthetic bile acid with anti-inflammatory properties in experimental and human cholesta
Externí odkaz:
https://doaj.org/article/604fc6dffe2b445992c1e43edd5e7284
Autor:
Nikolai P. Jaschke, Sophie Pählig, Anupam Sinha, Timon E. Adolph, Maria Ledesma Colunga, Maura Hofmann, Andrew Wang, Sylvia Thiele, Julian Schwärzler, Alexander Kleymann, Marc Gentzel, Herbert Tilg, Ben Wielockx, Lorenz C. Hofbauer, Martina Rauner, Andy Göbel, Tilman D. Rachner
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
A combination of cell line, transgenic mouse and human genetic data implicates a proinflammatory function of Dickkopf1 across malignant and non-malignant cells.
Externí odkaz:
https://doaj.org/article/08ca554bb4284badb614763c54f2ed47
Autor:
Joachim Hanna, Flavio Beke, Louise M. O’Brien, Chrysa Kapeni, Hung-Chang Chen, Valentina Carbonaro, Alexander B. Kim, Kamal Kishore, Timon E. Adolph, Mikkel-Ole Skjoedt, Karsten Skjoedt, Marc de la Roche, Maike de la Roche
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Th17 cells are critical players in the immunopathology of a range of autoimmune diseases. Here the authors implicate Hedgehog signaling in Th17 polarization and in the immunopathology of intestinal inflammation in murine models and suggest therapeuti
Externí odkaz:
https://doaj.org/article/37d7f063bb4e46ea82ad72c1a4b36302
Autor:
Moris Sangineto, Christoph Grander, Felix Grabherr, Lisa Mayr, Barbara Enrich, Julian Schwärzler, Marcello Dallio, Vidyasagar Naik Bukke, Archana Moola, Antonio Moschetta, Timon E. Adolph, Carlo Sabbà, Gaetano Serviddio, Herbert Tilg
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Alcohol-related liver disease (ALD) is a major cause of liver disease and represents a global burden, as treatment options are scarce. Whereas 90% of ethanol abusers develop alcoholic fatty liver disease (AFLD), only a minority evolves to steatohepat
Externí odkaz:
https://doaj.org/article/0ddb120444a241bca471377e37a98eb7
Autor:
Lisa Mayr, Felix Grabherr, Julian Schwärzler, Isabelle Reitmeier, Felix Sommer, Thomas Gehmacher, Lukas Niederreiter, Gui-Wei He, Barbara Ruder, Kai T. R. Kunz, Piotr Tymoszuk, Richard Hilbe, David Haschka, Clemens Feistritzer, Romana R. Gerner, Barbara Enrich, Nicole Przysiecki, Markus Seifert, Markus A. Keller, Georg Oberhuber, Susanne Sprung, Qitao Ran, Robert Koch, Maria Effenberger, Ivan Tancevski, Heinz Zoller, Alexander R. Moschen, Günter Weiss, Christoph Becker, Philip Rosenstiel, Arthur Kaser, Herbert Tilg, Timon E. Adolph
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Dietary lipids are linked to the development of inflammatory bowel diseases through unclear mechanisms. Here, the authors report that dietary polyunsaturated fatty acids trigger intestinal inflammation resembling aspects of Crohn’s disease, which i
Externí odkaz:
https://doaj.org/article/fc87842ee61c451c8bde60fdd9105dee
Autor:
Timon E. Adolph, Felix Grabherr, Lisa Mayr, Christoph Grander, Barbara Enrich, Alexander R. Moschen, Herbert Tilg
Publikováno v:
Journal of Obesity, Vol 2018 (2018)
Introduction. Obesity and related nonalcoholic fatty liver disease (NAFLD) are an emerging health care issue that imposes substantial morbidity to individuals. Growth and differentiation factor 15 (GDF15) limits food uptake, body weight, and energy b
Externí odkaz:
https://doaj.org/article/eeeb15e48ebf4ac89f7c355b0df6d639
Publikováno v:
Nature Reviews Gastroenterology & Hepatology. 19:753-767
Crohn's disease and ulcerative colitis, phenotypically comprising a spectrum of inflammatory bowel diseases (IBDs), spread globally during the westernization of lifestyle and dietary habits over the past few decades. Here, we review experimental and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e70776024232805158871e0a04ad254
https://doi.org/10.1038/s41575-022-00658-y
https://doi.org/10.1038/s41575-022-00658-y
Publikováno v:
Hepatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::128e428012c15104bf67a03a24a1e12d
https://doi.org/10.1097/hep.0000000000000386
https://doi.org/10.1097/hep.0000000000000386
Autor:
Julian Schwärzler, Lisa Mayr, Arnau Vich Vila, Felix Grabherr, Lukas Niederreiter, Maureen Philipp, Christoph Grander, Moritz Meyer, Almina Jukic, Simone Tröger, Barbara Enrich, Nicole Przysiecki, Markus Tschurtschenthaler, Felix Sommer, Irmgard Kronberger, Jakob Koch, Richard Hilbe, Michael W. Hess, Georg Oberhuber, Susanne Sprung, Qitao Ran, Robert Koch, Maria Effenberger, Nicole C. Kaneider, Verena Wieser, Markus A. Keller, Rinse K. Weersma, Konrad Aden, Philip Rosenstiel, Richard S. Blumberg, Arthur Kaser, Herbert Tilg, Timon E. Adolph
Publikováno v:
Gastroenterology, 162(6), 1690-1704. W B SAUNDERS CO-ELSEVIER INC
BACKGROUND & AIMS: Crohn's disease (CD) globally emerges with Westernization of lifestyle and nutritional habits. However, a specific dietary constituent that comprehensively evokes gut inflammation in human IBD remains elusive. Here, we aimed at del
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69c726146105d04b2becffd9f02b053d
https://doi.org/10.1053/j.gastro.2022.01.004
https://doi.org/10.1053/j.gastro.2022.01.004