Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Timofey S. Rozhdestvensky"'
Autor:
Irina V. Belozertseva, Dmitrijs D. Merkulovs, Helena Kaiser, Timofey S. Rozhdestvensky, Boris V. Skryabin
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9429 (2024)
Determining the estrous cycle stages in mice is essential for optimizing breeding strategies, synchronizing experimental timelines, and facilitating studies in behavior, drug testing, and genetics. It is critical for reducing the production of geneti
Externí odkaz:
https://doaj.org/article/faf523d859f145e9950b91a434bdbd4d
Autor:
Nadja I. Bork, Anna Kuret, Melanie Cruz Santos, Cristina E. Molina, Beate Reiter, Hermann Reichenspurner, Andreas Friebe, Boris V. Skryabin, Timofey S. Rozhdestvensky, Michaela Kuhn, Robert Lukowski, Viacheslav O. Nikolaev
Publikováno v:
Redox Biology, Vol 48, Iss , Pp 102179- (2021)
3′,5′-cyclic guanosine monophosphate (cGMP) is a druggable second messenger regulating cell growth and survival in a plethora of cells and disease states, many of which are associated with hypoxia. For example, in myocardial infarction and heart
Externí odkaz:
https://doaj.org/article/06f06ef82ac1467b9416c06fe88290d6
Autor:
Delf-Magnus Kummerfeld, Boris V. Skryabin, Juergen Brosius, Sergey Y. Vakhrushev, Timofey S. Rozhdestvensky
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8729 (2022)
Prader–Willi syndrome (PWS) is a complex neurodevelopmental disorder caused by the deletion or inactivation of paternally expressed imprinted genes at the chromosomal region 15q11–q13. The PWS-critical region (PWScr) harbors tandemly repeated non
Externí odkaz:
https://doaj.org/article/e1d82fe086c44198abdea4e537e87231
Autor:
Sharmilla Devi Jayasingam, Marimuthu Citartan, Anani Aila Mat Zin, Timofey S. Rozhdestvensky, Thean-Hock Tang, Ewe Seng Ch’ng
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 6994 (2022)
The dysregulation of microRNAs (miRNAs) has been known to play important roles in tumor development and progression. However, the understanding of the involvement of miRNAs in regulating tumor-associated macrophages (TAMs) and how these TAM-related m
Externí odkaz:
https://doaj.org/article/bad9c64df49545928518d0bef5403397
Autor:
Prabu Siva Sankar, Marimuthu Citartan, Aminah Ahmed Siti, Boris V. Skryabin, Timofey S. Rozhdestvensky, Goot Heah Khor, Thean Hock Tang
Publikováno v:
Iranian Journal of Microbiology, Vol 11, Iss 2 (2019)
Background and Objectives: Pfu DNA polymerase is an enzyme that exhibits the lowest error rate in the 3´ to 5´ exonuclease (proofreading) activity during DNA synthesis in Polymerase Chain Reactions (PCRs). This study was aimed to express and purify
Externí odkaz:
https://doaj.org/article/8c0f6334da53419cbf36a747f1cc7fec
Autor:
Delf-Magnus Kummerfeld, Carsten A. Raabe, Juergen Brosius, Dingding Mo, Boris V. Skryabin, Timofey S. Rozhdestvensky
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3613 (2021)
Prader-Willi syndrome (PWS) is a neurogenetic multifactorial disorder caused by the deletion or inactivation of paternally imprinted genes on human chromosome 15q11-q13. The affected homologous locus is on mouse chromosome 7C. The positional conserva
Externí odkaz:
https://doaj.org/article/a8b6a9929bee4a5186ea3dd1c7ffd308
Autor:
Dingding Mo, Xinping Li, Carsten A. Raabe, Timofey S. Rozhdestvensky, Boris V. Skryabin, Juergen Brosius
Publikováno v:
Cells, Vol 9, Iss 10, p 2196 (2020)
Alzheimer’s disease (AD) is an age-related detrimental dementia. Amyloid beta peptides (Aβ) play a crucial role in the pathology of AD. In familial AD, Aβ are generated from the full-length amyloid beta precursor protein (APP) via dysregulated pr
Externí odkaz:
https://doaj.org/article/43fd0b8b91f746e899bd068394eb13e4
Autor:
Mawethu Pascoe Bilibana, Marimuthu Citartan, Tzi Shien Yeoh, Timofey S. Rozhdestvensky, Thean-Hock Tang
Publikováno v:
Journal of Nucleic Acids, Vol 2017 (2017)
The binding specificity and affinity of aptamers have long been harnessed as the key elements in the development of aptamer-based assays, particularly aptasensing application. One promising avenue that is currently explored based on the specificity a
Externí odkaz:
https://doaj.org/article/0f8855baafb8475fbd984c30b78243bf
Autor:
Aliska K. Brugmans, Carolin Walter, Natalia Moreno, Carolin Göbel, Dörthe Holdhof, Flavia W. de Faria, Marc Hotfilder, Daniela Jeising, Michael C. Frühwald, Boris V. Skryabin, Timofey S. Rozhdestvensky, Lydia Wachsmuth, Cornelius Faber, Martin Dugas, Julian Varghese, Ulrich Schüller, Thomas K. Albert, Kornelius Kerl
Publikováno v:
Cellular and Molecular Neurobiology.
The BAF (BRG1/BRM-associated factor) chromatin remodelling complex is essential for the regulation of DNA accessibility and gene expression during neuronal differentiation. Mutations of its core subunit SMARCB1 result in a broad spectrum of pathologi
Autor:
Lisa Cole Burnett, Françoise Conte Auriol, Eric Bieth, Jean Pierre Salles, Juliette Salles, Maithé Tauber, Gwenaelle Diene, Catherine Molinas, Rudolph L. Leibel, Boris V. Skryabin, Isabelle Gennero, Timofey S. Rozhdestvensky, Sanaa Eddiry
Publikováno v:
Genetics in Medicine
Genetics in Medicine, 2021, 23 (9), pp.1664-1672. ⟨10.1038/s41436-021-01185-y⟩
Genetics in Medicine, 2021, 23 (9), pp.1664-1672. ⟨10.1038/s41436-021-01185-y⟩
International audience; Purpose: Prader-Willi syndrome (PWS) is a neurodevelopmental disorder with hypothalamic dysfunction due to deficiency of imprinted genes located on the 15q11-q13 chromosome. Among them, the SNORD116 gene appears critical for t