Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Timofey S, Rozhdestvensky"'
Autor:
Nadja I. Bork, Anna Kuret, Melanie Cruz Santos, Cristina E. Molina, Beate Reiter, Hermann Reichenspurner, Andreas Friebe, Boris V. Skryabin, Timofey S. Rozhdestvensky, Michaela Kuhn, Robert Lukowski, Viacheslav O. Nikolaev
Publikováno v:
Redox Biology, Vol 48, Iss , Pp 102179- (2021)
3′,5′-cyclic guanosine monophosphate (cGMP) is a druggable second messenger regulating cell growth and survival in a plethora of cells and disease states, many of which are associated with hypoxia. For example, in myocardial infarction and heart
Externí odkaz:
https://doaj.org/article/06f06ef82ac1467b9416c06fe88290d6
Autor:
Prabu Siva Sankar, Marimuthu Citartan, Aminah Ahmed Siti, Boris V. Skryabin, Timofey S. Rozhdestvensky, Goot Heah Khor, Thean Hock Tang
Publikováno v:
Iranian Journal of Microbiology, Vol 11, Iss 2 (2019)
Background and Objectives: Pfu DNA polymerase is an enzyme that exhibits the lowest error rate in the 3´ to 5´ exonuclease (proofreading) activity during DNA synthesis in Polymerase Chain Reactions (PCRs). This study was aimed to express and purify
Externí odkaz:
https://doaj.org/article/8c0f6334da53419cbf36a747f1cc7fec
Autor:
Aliska K. Brugmans, Carolin Walter, Natalia Moreno, Carolin Göbel, Dörthe Holdhof, Flavia W. de Faria, Marc Hotfilder, Daniela Jeising, Michael C. Frühwald, Boris V. Skryabin, Timofey S. Rozhdestvensky, Lydia Wachsmuth, Cornelius Faber, Martin Dugas, Julian Varghese, Ulrich Schüller, Thomas K. Albert, Kornelius Kerl
Publikováno v:
Cellular and Molecular Neurobiology.
The BAF (BRG1/BRM-associated factor) chromatin remodelling complex is essential for the regulation of DNA accessibility and gene expression during neuronal differentiation. Mutations of its core subunit SMARCB1 result in a broad spectrum of pathologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f431ab753ecc727dd8f6daa0fc8fb8e
https://doi.org/10.1007/s10571-023-01361-5
https://doi.org/10.1007/s10571-023-01361-5
Autor:
Dingding Mo, Xinping Li, Carsten A. Raabe, Timofey S. Rozhdestvensky, Boris V. Skryabin, Juergen Brosius
Publikováno v:
Cells, Vol 9, Iss 10, p 2196 (2020)
Alzheimer’s disease (AD) is an age-related detrimental dementia. Amyloid beta peptides (Aβ) play a crucial role in the pathology of AD. In familial AD, Aβ are generated from the full-length amyloid beta precursor protein (APP) via dysregulated pr
Externí odkaz:
https://doaj.org/article/43fd0b8b91f746e899bd068394eb13e4
Autor:
Mawethu Pascoe Bilibana, Marimuthu Citartan, Tzi Shien Yeoh, Timofey S. Rozhdestvensky, Thean-Hock Tang
Publikováno v:
Journal of Nucleic Acids, Vol 2017 (2017)
The binding specificity and affinity of aptamers have long been harnessed as the key elements in the development of aptamer-based assays, particularly aptasensing application. One promising avenue that is currently explored based on the specificity a
Externí odkaz:
https://doaj.org/article/0f8855baafb8475fbd984c30b78243bf
Autor:
Delf-Magnus, Kummerfeld, Boris V, Skryabin, Juergen, Brosius, Sergey Y, Vakhrushev, Timofey S, Rozhdestvensky
Publikováno v:
International journal of molecular sciences. 23(15)
Prader-Willi syndrome (PWS) is a complex neurodevelopmental disorder caused by the deletion or inactivation of paternally expressed imprinted genes at the chromosomal region 15q11-q13. The PWS-critical region (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fb25c92baf775165058f3dc5e5c24d84
https://pubmed.ncbi.nlm.nih.gov/35955861
https://pubmed.ncbi.nlm.nih.gov/35955861
Autor:
Lisa Cole Burnett, Françoise Conte Auriol, Eric Bieth, Jean Pierre Salles, Juliette Salles, Maithé Tauber, Gwenaelle Diene, Catherine Molinas, Rudolph L. Leibel, Boris V. Skryabin, Isabelle Gennero, Timofey S. Rozhdestvensky, Sanaa Eddiry
Publikováno v:
Genetics in Medicine
Genetics in Medicine, 2021, 23 (9), pp.1664-1672. ⟨10.1038/s41436-021-01185-y⟩
Genetics in Medicine, 2021, 23 (9), pp.1664-1672. ⟨10.1038/s41436-021-01185-y⟩
International audience; Purpose: Prader-Willi syndrome (PWS) is a neurodevelopmental disorder with hypothalamic dysfunction due to deficiency of imprinted genes located on the 15q11-q13 chromosome. Among them, the SNORD116 gene appears critical for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0080d05680200cd3deb6cb1061f247
http://europepmc.org/articles/PMC8460435
http://europepmc.org/articles/PMC8460435
Autor:
Ewe Seng Ch'ng, Kai-Cheen Ang, Timofey S. Rozhdestvensky, Nadja Bogdanova, Arseni Markoff, Thean-Hock Tang
Publikováno v:
Asia Pacific Journal of Molecular Biology and Biotechnology. :1-9
Repeated Pregnancy Loss (RPL) affects approximately 1 out of 20 pregnant women globally; it is traumatic for parents seeking parenthood with ensuing anxieties for the next pregnancy. M2/ANXA5 haplotype is a hereditary predisposition gene for thrombop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94ba32ee8142d91c894772771778469a
https://doi.org/10.35118/apjmbb.2021.029.1.01
https://doi.org/10.35118/apjmbb.2021.029.1.01
Autor:
Sharmilla Devi Jayasingam, Marimuthu Citartan, Anani Aila Mat Zin, Timofey S. Rozhdestvensky, Thean-Hock Tang, Ewe Seng Ch’ng
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 6994
The dysregulation of microRNAs (miRNAs) has been known to play important roles in tumor development and progression. However, the understanding of the involvement of miRNAs in regulating tumor-associated macrophages (TAMs) and how these TAM-related m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae59105409f50d24f36528e1240d81ec
https://pubmed.ncbi.nlm.nih.gov/35805995
https://pubmed.ncbi.nlm.nih.gov/35805995
Autor:
Dennis, Glaser, Alexander, Heinick, Julius R, Herting, Fabian, Massing, Frank U, Müller, Paul, Pauls, Timofey S, Rozhdestvensky, Jan S, Schulte, Matthias D, Seidl, Boris V, Skryabin, Frank, Stümpel, Uwe, Kirchhefer
Publikováno v:
The Journal of biological chemistry. 298(9)
The activity of protein phosphatase 2A (PP2A) is determined by the expression and localization of the regulatory B-subunits. PP2A-B56α is the dominant isoform of the B'-family in the heart. Its role in regulating the cardiac response to β-adrenergi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::436e762de8cbe31141e113f5e6703535
https://pubmed.ncbi.nlm.nih.gov/35963431
https://pubmed.ncbi.nlm.nih.gov/35963431