Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Timofey E. Tyugashev"'
Publikováno v:
Biomolecules, Vol 14, Iss 8, p 961 (2024)
Human terminal deoxynucleotidyl transferase (TdT) can catalyze template-independent DNA synthesis during the V(D)J recombination and DNA repair through nonhomologous end joining. The capacity for template-independent random addition of nucleotides to
Externí odkaz:
https://doaj.org/article/7de0eb4adcee41ecb55624fd8cc8d8e1
Autor:
Olga A. Kladova, Timofey E. Tyugashev, Aleksandr A. Miroshnikov, Daria S. Novopashina, Nikita A. Kuznetsov, Aleksandra A. Kuznetsova
Publikováno v:
Biomolecules, Vol 14, Iss 5, p 547 (2024)
In the cell, DNA polymerase β (Polβ) is involved in many processes aimed at maintaining genome stability and is considered the main repair DNA polymerase participating in base excision repair (BER). Polβ can fill DNA gaps formed by other DNA repai
Externí odkaz:
https://doaj.org/article/fc4f95582c30421b9c9ffa5cae6b97e5
Autor:
Anastasiia T. Davletgildeeva, Timofey E. Tyugashev, Mingxing Zhao, Nikita A. Kuznetsov, Alexander A. Ishchenko, Murat Saparbaev, Aleksandra A. Kuznetsova
Publikováno v:
Cells, Vol 12, Iss 14, p 1839 (2023)
Human Fe(II)/α-ketoglutarate-dependent dioxygenase ABH2 plays a crucial role in the direct reversal repair of nonbulky alkyl lesions in DNA nucleobases, e.g., N1-methyladenine (m1A), N3-methylcytosine (m3C), and some etheno derivatives. Moreover, AB
Externí odkaz:
https://doaj.org/article/b9f5236c15564bcaaeb5f351aba4027b
Autor:
Olga A. Kladova, Timofey E. Tyugashev, Elena S. Mikushina, Nikita A. Kuznetsov, Daria S. Novopashina, Aleksandra A. Kuznetsova
Publikováno v:
Cells, Vol 12, Iss 9, p 1300 (2023)
To maintain the integrity of the genome, there is a set of enzymatic systems, one of which is base excision repair (BER), which includes sequential action of DNA glycosylases, apurinic/apyrimidinic endonucleases, DNA polymerases, and DNA ligases. Nor
Externí odkaz:
https://doaj.org/article/659fe33fca8149e3ad5ac4aa5f0c6fa6
Autor:
Olga A. Kladova, Timofey E. Tyugashev, Elena S. Mikushina, Nikita O. Soloviev, Nikita A. Kuznetsov, Daria S. Novopashina, Aleksandra A. Kuznetsova
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 6; Pages: 5892
DNA polymerase β (Polβ) expression is essential for the cell’s response to DNA damage that occurs during natural cellular processes. Polβ is considered the main reparative DNA polymerase, whose role is to fill the DNA gaps arising in the base ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df11d460faf44cb3213fb77f3a7c2325
Autor:
Aleksandra A Kuznetsova, Timofey E Tyugashev, Irina V Alekseeva, Nadezhda A Timofeyeva, Olga S Fedorova, Nikita A Kuznetsov
Publikováno v:
Life science alliance. 5(12)
Terminal deoxynucleotidyltransferase (TdT) is a member of the DNA polymerase X family that is responsible for random addition of nucleotides to single-stranded DNA. We present investigation into the role of metal ions and specific interactions of dNT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::224af47cda1267f90f5210a49e5c8c2e
https://pubmed.ncbi.nlm.nih.gov/35914812
https://pubmed.ncbi.nlm.nih.gov/35914812
Autor:
Maria V. Lukina, Timofey E. Tyugashev, Olga S. Fedorova, Alexandra A. Kuznetsova, Yury N. Vorobjev, Nikita A. Kuznetsov
Publikováno v:
The Journal of Physical Chemistry B. 123:4878-4887
Human 8-oxoguanine-DNA glycosylase (hOGG1) possesses very high specificity for 8-oxoguanine (oxoG), even though this damaged base differs from normal guanine by only two atoms. Our aim was to determine the roles of certain catalytically important ami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a0ef0148286a4e15cd01b3d7449170b
https://doi.org/10.1021/acs.jpcb.9b02949
https://doi.org/10.1021/acs.jpcb.9b02949