Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Timofey D. Lebedev"'
Autor:
Alesya M. Mikheeva, Mikhail A. Bogomolov, Valentina A. Gasca, Mikhail V. Sementsov, Pavel V. Spirin, Vladimir S. Prassolov, Timofey D. Lebedev
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Imaging-based anticancer drug screens are becoming more prevalent due to development of automated fluorescent microscopes and imaging stations, as well as rapid advancements in image processing software. Automated cell imaging provides many
Externí odkaz:
https://doaj.org/article/b4b2da9c323f4178a43c92252caca866
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Understanding the molecular basis of fibrosis, the lethal complication of COVID-19, is urgent. By the analysis of RNA-sequencing data of SARS-CoV-2-infected cells combined with data mining we identified genes involved in COVID-19 progression
Externí odkaz:
https://doaj.org/article/af657faedb774b16b9c79f1776b9032d
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/29bbb599cea84f50b7afcfcbd775548f
Autor:
Timofey D. Lebedev, Elmira R. Vagapova, Vladimir I. Popenko, Olga G. Leonova, Pavel V. Spirin, Vladimir S. Prassolov
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Pediatric cancers represent a wide variety of different tumors, though they have unique features that distinguish them from adult cancers. Receptor tyrosine kinases KIT and TrkA functions in AML and NB, respectively, are well-characterized. Though ex
Externí odkaz:
https://doaj.org/article/0957f75265314e659be1679666207c8c
Autor:
Timofey D. Lebedev, Elmira R. Khabusheva, Sofia R. Mareeva, Karina A. Ivanenko, Alexey V. Morozov, Pavel V. Spirin, Petr M. Rubtsov, Anastasiya V. Snezhkina, Anna V. Kudryavtseva, Maxim I. Sorokin, Anton A. Buzdin, Vladimir S. Prassolov
Publikováno v:
The Journal of biological chemistry. 298(8)
Increased MAPK signaling is a hallmark of various cancers and is a central regulator of cell survival. Direct ERK1/2 inhibition is considered a promising approach to avoid ERK1/2 reactivation caused by upstream kinases BRAF, MEK1/2, and KRAS, as well