Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Timo Z. Nazari-Shafti"'
Publikováno v:
Cardiology and Therapy, Vol 13, Iss 1, Pp 39-67 (2024)
Abstract Numerous genetic and epidemiologic studies have demonstrated an association between elevated levels of lipoprotein(a) (Lp[a]) and cardiovascular disease. As a result, lowering Lp(a) levels is widely recognized as a promising strategy for red
Externí odkaz:
https://doaj.org/article/fa381b424afc440182e05fe485a4819a
Autor:
Dipthi Bachamanda Somesh, Kristin Klose, Janita A. Maring, Désirée Kunkel, Karsten Jürchott, Stephanie I. Protze, Oliver Klein, Grit Nebrich, Matthias Becker, Ulrike Krüger, Timo Z. Nazari-Shafti, Volkmar Falk, Andreas Kurtz, Manfred Gossen, Christof Stamm
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Background Direct cardiac reprogramming is currently being investigated for the generation of cells with a true cardiomyocyte (CM) phenotype. Based on the original approach of cardiac transcription factor-induced reprogramming of fibroblasts
Externí odkaz:
https://doaj.org/article/c371854fe11c4e7097810a43c278f286
Autor:
Jasper Iske, Andreas Schroeter, Samuel Knoedler, Timo Z. Nazari-Shafti, Leonard Wert, Maximilian J. Roesel, Felix Hennig, Adelheid Niehaus, Christian Kuehn, Fabio Ius, Volkmar Falk, Moritz Schmelzle, Arjang Ruhparwar, Axel Haverich, Christoph Knosalla, Stefan G. Tullius, Florian W. R. Vondran, Bettina Wiegmann
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Ex vivo machine perfusion (EVMP) is an emerging technique for preserving explanted solid organs with primary application in allogeneic organ transplantation. EVMP has been established as an alternative to the standard of care static-cold preservation
Externí odkaz:
https://doaj.org/article/1a275924082d40f1844c604cde28b754
Autor:
Timo Z. Nazari-Shafti, Heike Meyborg, Jasper Iske, Maximilian Schloss, Fabian Seeber, Aljona Friedrich, Vasileios Exarchos, Anja Richter, Volkmar Falk, Maximilian Y. Emmert
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
ObjectivesStethoscopes carry a significant risk for pathogen transmission. Here, the safe use and performance of a new, non-sterile, single-use stethoscope cover (SC), that is impermeable for pathogens, was investigated by different healthcare profes
Externí odkaz:
https://doaj.org/article/594575b162cd45a48193078af5a52ad3
Autor:
Vasileios Exarchos, Sebastian Neuber, Heike Meyborg, Costanza Giampietro, Nafsika Chala, Silvia Moimas, Hristian Hinkov, Friedrich Kaufmann, Francesca M. Pramotton, Katrin Krüger, Hector Rodriguez Cetina Biefer, Nikola Cesarovic, Dimos Poulikakos, Volkmar Falk, Maximilian Y. Emmert, Aldo Ferrari, Timo Z. Nazari-Shafti
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Thrombogenicity remains a major issue in cardiovascular implants (CVIs). Complete surficial coverage of CVIs by a monolayer of endothelial cells (ECs) prior to implantation represents a promising strategy but is hampered by the overall logistical com
Externí odkaz:
https://doaj.org/article/a908bb9962cb46e39877d00ea0e2cc9b
Autor:
Vasileios Exarchos, Ema Zacharova, Sebastian Neuber, Costanza Giampietro, Sarah E. Motta, Hristian Hinkov, Maximilian Y. Emmert, Timo Z. Nazari-Shafti
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Cardiovascular (CV) implants are still associated with thrombogenicity due to insufficient hemocompatibility. Endothelialization of their luminal surface is a promising strategy to increase their hemocompatibility. In this review, we provide a collec
Externí odkaz:
https://doaj.org/article/d84e4ad103bf48e7b9943d09486524c4
Treatment of Cardiac Fibrosis with Extracellular Vesicles: What Is Missing for Clinical Translation?
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10480 (2023)
Heart failure is the leading cause of morbidity and mortality and currently affects more than 60 million people worldwide. A key feature in the pathogenesis of almost all forms of heart failure is cardiac fibrosis, which is characterized by excessive
Externí odkaz:
https://doaj.org/article/b973fcbc607847dc8c58b961debca56c
Autor:
Timo Z. Nazari-Shafti, Vasileios Exarchos, Héctor Rodriguez Cetina Biefer, Nikola Cesarovic, Heike Meyborg, Volkmar Falk, Maximilian Y. Emmert
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
In the past 20 years, there have been several approaches to achieve cardioprotection or cardiac regeneration using a vast variety of cell therapies and remote ischemic pre-conditioning (RIPC). To date, substantial proof that either cell therapy or RI
Externí odkaz:
https://doaj.org/article/932564d7cb61456b8ecd72f89826defa
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 13000 (2021)
Excessive cardiac fibrosis plays a crucial role in almost all types of heart disease. Generally, cardiac fibrosis is a scarring process triggered in response to stress, injury, or aging and is characterized by the accumulation of activated myofibrobl
Externí odkaz:
https://doaj.org/article/9f9d9764141d4addac81b341d8d812e8
Autor:
Timo Z. Nazari-Shafti, Sebastian Neuber, Ana G. Duran, Vasileios Exarchos, Christien M. Beez, Heike Meyborg, Katrin Krüger, Petra Wolint, Johanna Buschmann, Roland Böni, Martina Seifert, Volkmar Falk, Maximilian Y. Emmert
Publikováno v:
Biomolecules, Vol 10, Iss 9, p 1353 (2020)
The cardioprotective properties of extracellular vesicles (EVs) derived from mesenchymal stromal cells (MSCs) are currently being investigated in preclinical studies. Although microRNAs (miRNAs) encapsulated in EVs have been identified as one compone
Externí odkaz:
https://doaj.org/article/ab9cea7710dd44f8bcf66cf0e3b9c361