Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Timo Sachsenheimer"'
Publikováno v:
Bio-Protocol, Vol 13, Iss 22 (2023)
Dolichyl phosphates (DolP) are ubiquitous lipids that are present in almost all eukaryotic membranes. They play a key role in several protein glycosylation pathways and the formation of glycosylphosphatidylinositol anchors. These lipids constitute on
Externí odkaz:
https://doaj.org/article/416a008455b949d3ad7f4040efd131c9
Autor:
Hana Nůsková, Marina V. Serebryakova, Anna Ferrer-Caelles, Timo Sachsenheimer, Christian Lüchtenborg, Aubry K. Miller, Britta Brügger, Larisa V. Kordyukova, Aurelio A. Teleman
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
S-acylation is the post-translational covalent attachment of fatty acids (FA) onto cysteines. Nuskova et al. find that exposure of cells to different FAs affects which FA is used to S-acylate GNAI proteins, thereby altering GNAI function and EGFR pat
Externí odkaz:
https://doaj.org/article/4b0fd691c75d4839863523c31d666fda
Autor:
Mouhannad Malek, Anna M. Wawrzyniak, Peter Koch, Christian Lüchtenborg, Manuel Hessenberger, Timo Sachsenheimer, Wonyul Jang, Britta Brügger, Volker Haucke
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The interplay between non-vesicular lipid transport, calcium signaling, and membrane dynamics is unclear. Here, the authors report a function for inositol triphosphate hydrolysis by the inositol 5-phosphatase INPP5A in controlling lipid exchange at i
Externí odkaz:
https://doaj.org/article/f08d9ea9e2a840c19b61c37be2ec8fca
Autor:
Elizabeth Ann Hambleton, Victor Arnold Shivas Jones, Ira Maegele, David Kvaskoff, Timo Sachsenheimer, Annika Guse
Publikováno v:
eLife, Vol 8 (2019)
Reef-building corals depend on intracellular dinoflagellate symbionts that provide nutrients. Besides sugars, the transfer of sterols is essential for corals and other sterol-auxotrophic cnidarians. Sterols are important cell components, and variants
Externí odkaz:
https://doaj.org/article/711a02d3b0324e62b1d34c48700f0f75
Autor:
Sandra Kleinecke, Sarah Richert, Livia de Hoz, Britta Brügger, Theresa Kungl, Ebrahim Asadollahi, Susanne Quintes, Judith Blanz, Rhona McGonigal, Kobra Naseri, Michael W Sereda, Timo Sachsenheimer, Christian Lüchtenborg, Wiebke Möbius, Hugh Willison, Myriam Baes, Klaus-Armin Nave, Celia Michèle Kassmann
Publikováno v:
eLife, Vol 6 (2017)
Impairment of peripheral nerve function is frequent in neurometabolic diseases, but mechanistically not well understood. Here, we report a novel disease mechanism and the finding that glial lipid metabolism is critical for axon function, independent
Externí odkaz:
https://doaj.org/article/278b7784adc34b6b9b3600532a3126a2
Autor:
Mathias J Gerl, Verena Bittl, Susanne Kirchner, Timo Sachsenheimer, Hanna L Brunner, Christian Lüchtenborg, Cagakan Özbalci, Hannah Wiedemann, Sabine Wegehingel, Walter Nickel, Per Haberkant, Carsten Schultz, Marcus Krüger, Britta Brügger
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153009 (2016)
Cell membranes contain hundreds to thousands of individual lipid species that are of structural importance but also specifically interact with proteins. Due to their highly controlled synthesis and role in signaling events sphingolipids are an intens
Externí odkaz:
https://doaj.org/article/19e9f4bf843f448f81a295eca5145236
Publikováno v:
Metabolites, Vol 2, Iss 1, Pp 57-76 (2012)
Lipids, such as phosphoinositides (PIPs) and diacylglycerol (DAG), are important signaling intermediates involved in cellular processes such as T cell receptor (TCR)-mediated signal transduction. Here we report identification and quantification of PI
Externí odkaz:
https://doaj.org/article/7be6cfe6a28f40ab94fa6067a6adc673
Autor:
Siavash Khosravi, Xenia Chelius, Ann-Katrin Unger, Daniela Rieger, Johanna Frickel, Timo Sachsenheimer, Christian Lüchtenborg, Rico Schieweck, Britta Brügger, Benedikt Westermann, Till Klecker, Walter Neupert, Max E. Harner
Publikováno v:
Journal of Cell Science. 136
Mitochondria are essential organelles of eukaryotic cells and are characterized by their unique and complex membrane system. They are confined from the cytosol by an envelope consisting of two membranes. Signals, metabolites, proteins and lipids have
Autor:
Max E. Harner, Walter Neupert, Till Klecker, Benedikt Westermann, Britta Brügger, Rico Schieweck, Christian Lüchtenborg, Timo Sachsenheimer, Ann-Katrin Unger, Xenia Chelius, Siavash Khosravi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f4dbb3b2810fe5cccc9d8ff3a94243d
https://doi.org/10.15252/rc.2022377467
https://doi.org/10.15252/rc.2022377467
Autor:
Siavash Khosravi, Xenia Chelius, Ann-Katrin Unger, Johanna Frickel, Timo Sachsenheimer, Christian Lüchtenborg, Rico Schieweck, Britta Brügger, Benedikt Westermann, Till Klecker, Walter Neupert, Max E. Harner
Mitochondria are essential organelles of eukaryotic cells that are characterized by their unique and complex membrane system. They are confined from the cytosol by an envelope consisting of two membranes. Signals, metabolites, proteins and lipids hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50097fef6a4839081be4910c1eca85b6
https://doi.org/10.1101/2022.04.09.487722
https://doi.org/10.1101/2022.04.09.487722