Predicting treatment response to vancomycin using bacterial DNA load as a pharmacodynamic marker in premature and very low birth weight neonates: A population PKPD study

Autor: Amadou Samb, Rimke De Kroon, Koos Dijkstra, Marre Van Den Brand, Martine Bos, Frank Van Den Dungen, Agnes Veldkamp, Bram Wilhelm, Timo R. De Haan, Yuma A. Bijleveld, Marceline Tutu Van Furth, Paul Savelkoul, Noortje Swart, Ron Mathot, Mirjam Van Weissenbruch

Publikováno v: Frontiers in Pharmacology, Vol 14 (2023)

Background: While positive blood cultures are the gold standard for late-onset sepsis (LOS) diagnosis in premature and very low birth weight (VLBW) newborns, these results can take days, and early markers of possible treatment efficacy are lacking. T

Externí odkaz: https://doaj.org/article/f81feb8396f04f48bf87ede3e5535cd9

Saliva as a sampling matrix for therapeutic drug monitoring of gentamicin in neonates: A prospective population pharmacokinetic and simulation study

Autor: Yuma A. Bijleveld, Adam F. Cohen, Michiel J van Esdonk, Gertjan J. Driessen, Anton H. van Kaam, Matthijs D. Kruizinga, Ron A. A. Mathôt, Willemijn van Heel, Rik F E Stuurman, Younes Tallahi, Amadou Samb, Timo R. de Haan

Publikováno v: British Journal of Clinical Pharmacology, 88(4), 1845-1855. Wiley
British journal of clinical pharmacology. Wiley-Blackwell

Aims Therapeutic drug monitoring (TDM) of gentamicin in neonates is recommended for safe and effective dosing and is currently performed by plasma sampling, which is an invasive and painful procedure. In this study, feasibility of a non-invasive gent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957dc3097280750152bbd849e6a0e2ff
https://cris.maastrichtuniversity.nl/en/publications/9ed16080-4525-4633-966e-266d58670634

Outcome Prediction and Inter-Rater Comparison of Four Brain Magnetic Resonance Imaging Scoring Systems of Infants with Perinatal Asphyxia and Therapeutic Hypothermia

Autor: Juliette F, Langeslag, Floris, Groenendaal, Stefan D, Roosendaal, Linda S, de Vries, Wes, Onland, Mariska M G, Leeflang, Paul F C, Groot, Anton H, van Kaam, Timo R, de Haan, Alexandra, Zecic

Publikováno v: Neonatology, 119(3), 311-319. S. Karger AG
Langeslag, J F, Groenendaal, F, Roosendaal, S D, de Vries, L S, Onland, W, Leeflang, M M G, Groot, P F C, van Kaam, A H & de Haan, T R 2022, ' Outcome Prediction and Inter-Rater Comparison of Four Brain Magnetic Resonance Imaging Scoring Systems of Infants with Perinatal Asphyxia and Therapeutic Hypothermia ', Neonatology, vol. 119, no. 3, pp. 311-319 . https://doi.org/10.1159/000522629

Introduction: The brain magnetic resonance imaging (MRI) result is a major predictor for the outcome of term infants with perinatal asphyxia who underwent therapeutic hypothermia. In daily practice, no uniform method is used to assess these images. P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::336a85b1cd55585a75c7c1df65a41ddf
https://pubmed.ncbi.nlm.nih.gov/35358976

Neonatal gram negative and Candida sepsis survival and neurodevelopmental outcome at the corrected age of 24 months.

Autor: Timo R de Haan, Loes Beckers, Rogier C J de Jonge, Lodewijk Spanjaard, Letty van Toledo, Dasja Pajkrt, Aleid G van Wassenaer-Leemhuis, Johanna H van der Lee

Publikováno v: PLoS ONE, Vol 8, Iss 3, p e59214 (2013)

ObjectivesTo evaluate the long term neurodevelopmental outcome of premature infants exposed to either gram- negative sepsis (GNS) or neonatal Candida sepsis (NCS), and to compare their outcome with premature infants without sepsis.MethodsHistorical c

Externí odkaz: https://doaj.org/article/f1d88e28e276419fbfa21b2c356f7fa1

The Thompson Encephalopathy Score and Short-Term Outcomes in Asphyxiated Newborns Treated With Therapeutic Hypothermia

Autor: Jeroen Dudink, Alexandra Zecic, Arno van Heijst, Wes Onland, Jeroen R. Vermeulen, Patricia Thorsen, Monique Rijken, Henrika L.M. van Straaten, Martine C. Jansen-van der Weide, Timo R. de Haan, Anton H. van Kaam, Peter H. Dijk, Floris Groenendaal, Filip Cools, Inge A. Zonnenberg, Koen P. Dijkman

Publikováno v: Pediatric neurology, 60, 49-53. Elsevier Inc.
Pediatric neurology, 60, 49-53. ELSEVIER SCIENCE INC
Pediatric Neurology, 60, 49-53. Elsevier Inc.
Pediatric Neurology, 60, 49-53
Pediatric Neurology, 60, 49. Elsevier Inc.
Thorsen, P, Jansen-van der Weide, M C, Groenendaal, F, Onland, W, van Straaten, H L M, Zonnenberg, I, Vermeulen, J R, Dijk, P H, Dudink, J, Rijken, M, van Heijst, A F, Dijkman, K P, Cools, F, Zecic, A, van Kaam, A H & Haan, T R 2016, ' The Thompson Encephalopathy Score and Short-Term Outcomes in Asphyxiated Newborns Treated With Therapeutic Hypothermia ', Pediatric Neurology, vol. 60, pp. 49-53 . https://doi.org/10.1016/j.pediatrneurol.2016.03.014

BACKGROUND: The Thompson encephalopathy score is a clinical score to assess newborns suffering from perinatal asphyxia. Previous studies revealed a high sensitivity and specificity of the Thompson encephalopathy score for adverse outcomes (death or s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::473bb0d18b545582781a0cf9d37b1807
https://research.rug.nl/en/publications/1178dc08-1a62-4a0c-85ff-f7af8e72e083