Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Timo Laaksonen"'
Autor:
Eija Ilvesroiha, Patrick Lauren, Natsumi Uema, Kanako Kikuchi, Yuuki Takashima, Timo Laaksonen, Tatu Lajunen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The off-target effects of light-activated or targeted liposomes are difficult to distinguish in traditional well plate experiments. Additionally, the absence of fluid flow in traditional cell models can lead to overestimation of nanoparticle
Externí odkaz:
https://doaj.org/article/2d54205d20e7462791702cbd6e58e738
Autor:
Zachary J. Smith, Changwon Lee, Tatu Rojalin, Randy P. Carney, Sidhartha Hazari, Alisha Knudson, Kit Lam, Heikki Saari, Elisa Lazaro Ibañez, Tapani Viitala, Timo Laaksonen, Marjo Yliperttula, Sebastian Wachsmann-Hogiu
Publikováno v:
Journal of Extracellular Vesicles, Vol 4, Iss 0, Pp 1-15 (2015)
Current analysis of exosomes focuses primarily on bulk analysis, where exosome-to-exosome variability cannot be assessed. In this study, we used Raman spectroscopy to study the chemical composition of single exosomes. We measured spectra of individua
Externí odkaz:
https://doaj.org/article/c8a961dc22c84fe0883483f6f400f53e
Autor:
Patrick Laurén, Petter Somersalo, Irina Pitkänen, Yan-Ru Lou, Arto Urtti, Jouni Partanen, Jukka Seppälä, Mari Madetoja, Timo Laaksonen, Antti Mäkitie, Marjo Yliperttula
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183487 (2017)
Hydrogel nanomaterials, especially those that are of non-human and non-animal origins, have great potential in biomedical and pharmaceutical sciences due to their versatility and inherent soft-tissue like properties. With the ability to simulate nati
Externí odkaz:
https://doaj.org/article/957651b48dd947a68f05135fa166f3ce
Autor:
Leena Hanski, Natalja Genina, Hanna Uvell, Kristina Malinovskaja, Åsa Gylfe, Timo Laaksonen, Ruzica Kolakovic, Ermei Mäkilä, Jarno Salonen, Jouni Hirvonen, Mikael Elofsson, Niklas Sandler, Pia M Vuorela
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115115 (2014)
Given the established role of Chlamydia spp. as causative agents of both acute and chronic diseases, search for new antimicrobial agents against these intracellular bacteria is required to promote human health. Isoflavones are naturally occurring phy
Externí odkaz:
https://doaj.org/article/79d6f16c9bfa402aa6e13b698806728e
Autor:
Jussi Isokuortti, Thomas Griebenow, Jan-Simon von Glasenapp, Tim Raeker, Mihail A. Filatov, Timo Laaksonen, Rainer Herges, Nikita A. Durandin
Diazocine is a bridged azobenzene with both phenyl rings connected by a CH2-CH2 group. Despite this rather small structural difference, diazocine exhibits improved properties over azobenzene as a photoswitch, such as high switching efficiencies, very
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::363b2da16219caed2a7ed575d6395c58
https://doi.org/10.26434/chemrxiv-2023-nq0w0
https://doi.org/10.26434/chemrxiv-2023-nq0w0
Autor:
Lukas Hahn, Theresa Zorn, Josef Kehrein, Tobias Kielholz, Anna-Lena Ziegler, Stefan Forster, Benedikt Sochor, Ekaterina S. Lisitsyna, Nikita A. Durandin, Timo Laaksonen, Vladimir Aseyev, Christoph Sotriffer, Kay Saalwächter, Maike Windbergs, Ann-Christin Pöppler, Robert Luxenhofer
Polymer self-assembly leading to cooling-induced hydrogel formation is relatively rare for synthetic polymers and typically relies on H-bonding between repeat units. Here, we describe a non-H-bonding mechanism for a cooling-induced reversible order-o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b09646d1c5db005c1776e939852fb5
https://trepo.tuni.fi/handle/10024/147463
https://trepo.tuni.fi/handle/10024/147463
Autor:
Kaisa Rautaniemi, Thomas John, Maximilian Richter, Benedikt C. Huck, Jacopo Zini, Brigitta Loretz, Claus-Michael Lehr, Elina Vuorimaa-Laukkanen, Ekaterina Lisitsyna, Timo Laaksonen
The analysis of nanoparticle (NP) dynamics in live cell studies by video tracking provides detailed information on their interactions and trafficking in the cells. Although the video analysis is not yet routinely used in NP studies, the equipment sui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a806066ed17609fa537d678e3da93d22
https://trepo.tuni.fi/handle/10024/145074
https://trepo.tuni.fi/handle/10024/145074
Autor:
Timo Laaksonen, Clare J. Strachan, Marcin Skotnicki, Tiina Lipiäinen, Jukka Saarinen, Martin Dračínský, Kaisa Rautaniemi, Elina Vuorimaa-Laukkanen
Publikováno v:
Characterization of Pharmaceutical Nano and Microsystems
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0aa76dbe2db7c22dae72de080476b2ed
https://doi.org/10.1002/9781119414018.ch2
https://doi.org/10.1002/9781119414018.ch2
Autor:
Line Hagner Nielsen, Dunja Novakovic, Clare J. Strachan, Leena Peltonen, Antti Isomäki, Timo Laaksonen, Sara J. Fraser-Miller
Publikováno v:
Molecular Pharmaceutics
Novakovic, D, Peltonen, L, Isomäki, A, Fraser-Miller, S J, Nielsen, L H, Laaksonen, T & Strachan, C J 2020, ' Surface Stabilization and Dissolution Rate Improvement of Amorphous Compacts with Thin Polymer Coatings: Can We Have It All? ', Molecular Pharmaceutics, vol. 17, pp. 1248-1260 . https://doi.org/10.1021/acs.molpharmaceut.9b01263
Novakovic, D, Peltonen, L, Isomäki, A, Fraser-Miller, S J, Nielsen, L H, Laaksonen, T & Strachan, C J 2020, ' Surface Stabilization and Dissolution Rate Improvement of Amorphous Compacts with Thin Polymer Coatings: Can We Have It All? ', Molecular Pharmaceutics, vol. 17, pp. 1248-1260 . https://doi.org/10.1021/acs.molpharmaceut.9b01263
The distinction between surface and bulk crystallization of amorphous pharmaceuticals, as well as the importance of surface crystallization for pharmaceutical performance, is becoming increasingly evident. An emerging strategy in stabilizing the amor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a27b4d826bfd56c9de52723c31932a
https://doi.org/10.1021/acs.molpharmaceut.9b01263
https://doi.org/10.1021/acs.molpharmaceut.9b01263
Autor:
Vili-Veli Auvinen, Patrick Laurén, Boxuan Shen, Jussi Isokuortti, Nikita Durandin, Tatu Lajunen, Veikko Linko, Timo Laaksonen
Publikováno v:
Cellulose
Funding Information: The authors acknowledge Alexander Efimov and Ekaterina Lisitsyna for the production of the micelle labels. We would like to thank Puja Gangurde for aid in the laboratory work. Ti.L., J.I., and V.-V.A. acknowledge funding from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5057912451ffd957106075f6cc2e1733