Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Timo L M Ten Hagen"'
Autor:
Elena Gurrieri, Giulia Carradori, Michela Roccuzzo, Michael Pancher, Daniele Peroni, Romina Belli, Caterina Trevisan, Michela Notarangelo, Wen-Qiu Huang, Agata S. A. Carreira, Alessandro Quattrone, Guido Jenster, Timo L. M. Ten Hagen, Vito Giuseppe D’Agostino
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-19 (2024)
Abstract Background Extracellular vesicles (EVs) are cell-secreted particles conceived as natural vehicles for intercellular communication. The capacity to entrap heterogeneous molecular cargoes and target specific cell populations through EV functio
Externí odkaz:
https://doaj.org/article/f77acac84bd9414abd92b0f3f19993d5
Autor:
Ziyun Cheng, Seth-Frerich Fobian, Elena Gurrieri, Mohamadreza Amin, Vito Giuseppe D’Agostino, Mojtaba Falahati, Sara Zalba, Reno Debets, María J. Garrido, Mesha Saeed, Ann L. B. Seynhaeve, Hayri E. Balcioglu, Timo L. M. ten Hagen
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-39 (2024)
Abstract Immunotherapy has become an important part of the oncotherapy arsenal. Its applicability in various cancer types is impressive, as well as its use of endogenous mechanisms to achieve desired ends. However, off-target or on-target-off-tumor t
Externí odkaz:
https://doaj.org/article/9b00f680f44c4519acc61e9173772fa0
Autor:
Henriëtte S de Bruijn, Sander Brooks, Angélique van der Ploeg-van den Heuvel, Timo L M Ten Hagen, Ellen R M de Haas, Dominic J Robinson
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148850 (2016)
BACKGROUND:Light fractionation significantly increases the efficacy of 5-aminolevulinic acid (ALA) based photodynamic therapy (PDT) using the nano-emulsion based gel formulation BF-200. PDT using BF-200 ALA has recently been clinically approved and i
Externí odkaz:
https://doaj.org/article/ca373e4cf5d64fe99e0de301e9ac5466
Autor:
Slávka Kaščáková, Leo J Hofland, Henriette S De Bruijn, Yunpeng Ye, Samuel Achilefu, Katy van der Wansem, Angelique van der Ploeg-van den Heuvel, Peter M van Koetsveld, Michael P Brugts, Aart-Jan van der Lelij, Henricus J C M Sterenborg, Timo L M Ten Hagen, Dominic J Robinson, Martin P van Hagen
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104448 (2014)
Photodynamic therapy (PDT) is an established treatment modality, used mainly for anticancer therapy that relies on the interaction of photosensitizer, light and oxygen. For the treatment of pathologies in certain anatomical sites, improved targeting
Externí odkaz:
https://doaj.org/article/9b9219fc88574fb5bd0233b77d0ce699
Autor:
Jan W P Kuiper, Remco van Horssen, Frank Oerlemans, Wilma Peters, Michiel M T van Dommelen, Mariska M te Lindert, Timo L M ten Hagen, Edwin Janssen, Jack A M Fransen, Bé Wieringa
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e5030 (2009)
BACKGROUND: Creatine Kinases (CK) catalyze the reversible transfer of high-energy phosphate groups between ATP and phosphocreatine, thereby playing a storage and distribution role in cellular energetics. Brain-type CK (CK-B) deficiency is coupled to
Externí odkaz:
https://doaj.org/article/0f27f5349e55480890b29f11b526bb2f
Autor:
Suliman Khan, William C. Cho, Afrooz Sepahvand, Sara Haji Hosseinali, Arif Hussain, Mohammad Mahdi Nejadi Babadaei, Majid Sharifi, Mojtaba Falahati, Laila Abdulmohsen Jaragh-Alhadad, Timo L. M. ten Hagen, Xin Li
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-22 (2023)
Abstract It is essential to develop ultrasensitive biosensors for cancer detection and treatment monitoring. In the development of sensing platforms, metal-organic frameworks (MOFs) have received considerable attention as potential porous crystalline
Externí odkaz:
https://doaj.org/article/c6f1ae6c85ed4709aec8d20b595b293e
Publikováno v:
Small Science, Vol 3, Iss 8, Pp n/a-n/a (2023)
In nanomedicine, lipid‐based nanoparticles (NPs) such as liposomes (LPs) have established an important position. Precise delineation of NP interaction with cells and detailed characterization of activity are becoming essential, which mainly rely on
Externí odkaz:
https://doaj.org/article/d238a97915b341ba9e28f4f85692384f
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-26 (2022)
Abstract Nowadays, nano-/micro-motors are considered as powerful tools in different areas ranging from cleaning all types of contaminants, to development of Targeted drug delivery systems and diagnostic activities. Therefore, the development and appl
Externí odkaz:
https://doaj.org/article/0e8d053972014a1a8861905ea1f9fb90
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Endothelial cells and pericytes are highly dynamic vascular cells and several subtypes, based on their spatiotemporal dynamics or molecular expression, are believed to exist. The interaction between endothelial cells and pericytes is of impo
Externí odkaz:
https://doaj.org/article/11a3f948694a43929e02d6ec208222fe
Autor:
Timo L. M. ten Hagen, Matthew R. Dreher, Sara Zalba, Ann L. B. Seynhaeve, Mohamadreza Amin, Li Li, Dieter Haemmerich
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-17 (2021)
Ten Hagen et al. developed a computational model to simulate intravascular triggered drug delivery systems (IV-DDS), which they validated using quantitative intravital microscopy in mice. Their model potentially enables the engineering of more effica
Externí odkaz:
https://doaj.org/article/292013dcfbbe4560a8cff83d92bc8106