Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Timo Kanninen"'
Autor:
Sara Haydar, Florin Grigorescu, Mădălina Vintilă, Yannick Cogne, Corinne Lautier, Yildiz Tutuncu, Jean Frederic Brun, Jean Marie Robine, Michel Pugeat, Christophe Normand, Patrick Poucheret, Monica Livia Gheorghiu, Carmen Georgescu, Corin Badiu, Nicoleta Băculescu, Eric Renard, Dorina Ylli, Stephanie Badiou, Thibault Sutra, Jean Paul Cristol, Jacques Mercier, Ramon Gomis, Josep Maria Macias, Serghey Litvinov, Elza Khusnutdinova, Catalina Poiana, Renato Pasquali, Davide Lauro, Giorgio Sesti, Sabrina Prudente, Vincenzo Trischitta, Agathocles Tsatsoulis, Sonia Abdelhak, Abdelhamid Barakat, Akila Zenati, Agron Ylli, Ilhan Satman, Timo Kanninen, Yves Rinato, Sasa Missoni
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0214122 (2019)
Branched chain amino acids (BCAA) are essential elements of the human diet, which display increased plasma levels in obesity and regained particular interest as potential biomarkers for development of diabetes. To define determinants of insulin resis
Externí odkaz:
https://doaj.org/article/8c27de3eae724884a16e3faed7dfd99e
Autor:
Sara Haydar, Thomas Paillot, Christophe Fagot, Yannick Cogne, Athanasios Fountas, Yildiz Tutuncu, Madalina Vintila, Agathocles Tsatsoulis, Pham Thanh Chi, Patrick Garandeau, Dan Chetea, Corin Badiu, Monica Gheorghiu, Dorina Ylli, Corinne Lautier, Morana Jarec, Louis Monnier, Christophe Normand, Jelena Šarac, Abdelhamid Barakat, Sasa Missoni, Michel Pugeat, Patrick Poucheret, Felicia Hanzu, Ramon Gomis, Josep Maria Macias, Serghey Litvinov, Elza Khusnutdinova, Catalina Poiana, Renato Pasquali, Davide Lauro, Giorgio Sesti, Vincenzo Trischitta, Sonia Abdelhak, Akila Zenati, Agron Ylli, Ilhan Satman, Timo Kanninen, Yves Rinato, Florin Grigorescu
Publikováno v:
Nutrients, Vol 10, Iss 10, p 1392 (2018)
Branched-chained amino acids (BCAA) are essential dietary components for humans and can act as potential biomarkers for diabetes development. To efficiently estimate dietary intake, we developed a BCAA database for 1331 food items found in the French
Externí odkaz:
https://doaj.org/article/f139773dd9e0488ab80e5700ba000012
Autor:
Natalie R. van Zuydam, Alexander Stiby, Moustafa Abdalla, Erin Austin, Emma H. Dahlström, Stela McLachlan, Efthymia Vlachopoulou, Emma Ahlqvist, Chen Di Liao, Niina Sandholm, Carol Forsblom, Anubha Mahajan, Neil R. Robertson, N. William Rayner, Eero Lindholm, Juha Sinisalo, Markus Perola, Milla Kallio, Emily Weiss, Jackie Price, Andrew Paterson, Barbara Klein, Veikko Salomaa, Colin N.A. Palmer, Per-Henrik Groop, Leif Groop, Mark I. McCarthy, Mariza de Andrade, Andrew P. Morris, Jemma C. Hopewell, Helen M. Colhoun, Iftikhar J. Kullo, Sólveig Grétarsdóttir, Guðmar Þorleifsson, Unnur þorsteinsdóttir, Kari Stefansson, Michael Mark, Timo Kanninen, Barbara Thorand, Giuseppe Remuzzi, David Dunger, Angela Shore, Ulf Smith, Seppo Ylä-Herttuala, Claudio Cobelli, Riccardo Bellazzi, Ele Ferrannini, Carlo Patrono, Pirjo Nuutila, Paul McKeague, Birgit Steckel-Hamann, Li-ming Gan, Everson Nogoceke, Piero Tortoli, Bernd Jablonka, Mary-Julia Brosnan
Publikováno v:
Circulation. Genomic and Precision Medicine
Van Zuydam, N R, Stiby, A, Abdalla, M, Dahlstrom, EH, McLachlan, S, Vlachopoulou, E, Price, J F, Ahlqvist, E, Di Liao, C, Sandholm, N, Forsblom, C, Mahajan, A, Robertson, N R, Rayner, N W, Lindholm, E, Sinisalo, J, Perola, M, Kallio, M, Weiss, E, Paterson, A, Klein, B, Salomaa, V, McCarthy, M, de Andrade, M, Morris, AP, Hopewell, JC, Colhoun, H M & Kullo, IJ 2021, ' A genome-wide association study of peripheral artery disease ', Circulation: Genomic and Precision Medicine . https://doi.org/10.1161/CIRCGEN.119.002862
Circ. Genom. Precis. Med. 14:e002862 (2021)
Circulation: Genomic and Precision Medicine
Van Zuydam, N R, Stiby, A, Abdalla, M, Dahlstrom, EH, McLachlan, S, Vlachopoulou, E, Price, J F, Ahlqvist, E, Di Liao, C, Sandholm, N, Forsblom, C, Mahajan, A, Robertson, N R, Rayner, N W, Lindholm, E, Sinisalo, J, Perola, M, Kallio, M, Weiss, E, Paterson, A, Klein, B, Salomaa, V, McCarthy, M, de Andrade, M, Morris, AP, Hopewell, JC, Colhoun, H M & Kullo, IJ 2021, ' A genome-wide association study of peripheral artery disease ', Circulation: Genomic and Precision Medicine . https://doi.org/10.1161/CIRCGEN.119.002862
Circ. Genom. Precis. Med. 14:e002862 (2021)
Circulation: Genomic and Precision Medicine
Supplemental Digital Content is available in the text.
Background: Peripheral artery disease (PAD) affects >200 million people worldwide and is associated with high mortality and morbidity. We sought to identify genomic variants associated with
Background: Peripheral artery disease (PAD) affects >200 million people worldwide and is associated with high mortality and morbidity. We sought to identify genomic variants associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1331a7c40e7d9286577d43c5d5fbb16a
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-458405
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-458405
Autor:
Natalie R. van Zuydam, Claes Ladenvall, Benjamin F. Voight, Rona J. Strawbridge, Juan Fernandez-Tajes, N. William Rayner, Neil R. Robertson, Anubha Mahajan, Efthymia Vlachopoulou, Anuj Goel, Marcus E. Kleber, Christopher P. Nelson, Lydia Coulter Kwee, Tõnu Esko, Evelin Mihailov, Reedik Mägi, Lili Milani, Krista Fischer, Stavroula Kanoni, Jitender Kumar, Ci Song, Jaana A. Hartiala, Nancy L. Pedersen, Markus Perola, Christian Gieger, Annette Peters, Liming Qu, Sara M. Willems, Alex S.F. Doney, Andrew D. Morris, Yan Zheng, Giorgio Sesti, Frank B. Hu, Lu Qi, Markku Laakso, Unnur Thorsteinsdottir, Harald Grallert, Cornelia van Duijn, Muredach P. Reilly, Erik Ingelsson, Panos Deloukas, Sek Kathiresan, Andres Metspalu, Svati H. Shah, Juha Sinisalo, Veikko Salomaa, Anders Hamsten, Nilesh J. Samani, Winfried März, Stanley L. Hazen, Hugh Watkins, Danish Saleheen, Andrew P. Morris, Helen M. Colhoun, Leif Groop, Mark I. McCarthy, Colin N.A. Palmer, John Danesh, Jeanette Erdmann, Dongfeng Gu, Jaspal S. Kooner, Robert Roberts, Heribert Schunkert, Themistocles L. Assimes, Stefan Blankenberg, Bernhard O. Boehm, John C. Chambers, Robert Clarke, Rory Collins, George Dedoussis, Paul W. Franks, G. Kees Hovingh, Bong-Jo Kim, Terho Lehtimäki, Ruth McPherson, Markku S Nieminen, Christopher O’Donnell, Samuli Ripatti, Manjinder S Sandhu, Stefan Schreiber, Agneta Siegbahn, Cristen J. Willer, Pierre A. Zalloua, Michael Mark, Timo Kanninen, Barbara Thorand, Giuseppe Remuzzi, David Dunger, Angela Shore, Ulf Smith, Per-Henrik Groop, Seppo Ylä-Herttuala, Claudio Cobelli, Riccardo Bellazzi, Ele Ferrannini, Carlo Patrono, Pirjo Nuutila, Paul McKeague, Birgit Steckel-Hamann, Li-ming Gan, Everson Nogoceke, Piero Tortoli, Bernd Jablonka, Mary-Julia Brosnan
Publikováno v:
Circ. Genom. Precis. Med. 13, 640-648 (2020)
Van Zuydam, N R, Ladenvall, C, Voight, B F, Strawbridge, R J, Fernandez-tajes, J, Rayner, N W, Robertson, N R, Mahajan, A, Vlachopoulou, E, Goel, A, Kleber, M E, Nelson, C P, Kwee, L C, Esko, T, Mihailov, E, Mägi, R, Milani, L, Fischer, K, Kanoni, S, Kumar, J, Song, C, Hartiala, J A, Pedersen, N L, Perola, M, Gieger, C, Peters, A, Qu, L, Willems, S M, Doney, A S F, Morris, A P, Zheng, Y, Sesti, G, Hu, F B, Qi, L, Laakso, M, Thorsteinsdottir, U, Grallert, H, Van Duijn, C, Reilly, M P, Ingelsson, E, Deloukas, P, Kathiresan, S, Metspalu, A, Shah, S H, Sinisalo, J, Salomaa, V, Hamsten, A, Samani, N J, März, W, Hazen, S L, Watkins, H, Saleheen, D, Morris, A P, Colhoun, H M, Groop, L, Mccarthy, M I, Palmer, C N A, Danesh, J, Erdmann, J, Gu, D, Kooner, J S, Roberts, R, Schunkert, H, Assimes, T L, Blankenberg, S, Boehm, B O, Chambers, J C, Clarke, R, Collins, R, Dedoussis, G, Franks, P W, Hovingh, G K, Kim, B, Lehtimäki, T, Mcpherson, R, Nieminen, M S, O’donnell, C, Ripatti, S, Sandhu, M S, Schreiber, S, Siegbahn, A, Willer, C J, Zalloua, P A, Mark, M, Kanninen, T, Thorand, B, Remuzzi, G, Dunger, D, Shore, A, Smith, U, Groop, P, Ylä-herttuala, S, Cobelli, C, Bellazzi, R, Ferrannini, E, Patrono, C, Nuutila, P, Mckeague, P, Steckel-hamann, B, Gan, L, Nogoceke, E, Tortoli, P, Jablonka, B & Brosnan, M 2020, ' Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus ', Circulation: Genomic and precision medicine, vol. 13, no. 6 . https://doi.org/10.1161/CIRCGEN.119.002769
2020, ' Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus ', Circulation: Genomic and Precision Medicine, vol. 13, no. 6, pp. e002769 . https://doi.org/10.1161/CIRCGEN.119.002769
Circulation. Genomic and Precision Medicine
Circulation-Genomic and Precision Medicine, 13(6), 640-648. Lippincott Williams & Wilkins
Van Zuydam, N R, Ladenvall, C, Voight, B F, Strawbridge, R J, Fernandez-tajes, J, Rayner, N W, Robertson, N R, Mahajan, A, Vlachopoulou, E, Goel, A, Kleber, M E, Nelson, C P, Kwee, L C, Esko, T, Mihailov, E, Mägi, R, Milani, L, Fischer, K, Kanoni, S, Kumar, J, Song, C, Hartiala, J A, Pedersen, N L, Perola, M, Gieger, C, Peters, A, Qu, L, Willems, S M, Doney, A S F, Morris, A P, Zheng, Y, Sesti, G, Hu, F B, Qi, L, Laakso, M, Thorsteinsdottir, U, Grallert, H, Van Duijn, C, Reilly, M P, Ingelsson, E, Deloukas, P, Kathiresan, S, Metspalu, A, Shah, S H, Sinisalo, J, Salomaa, V, Hamsten, A, Samani, N J, März, W, Hazen, S L, Watkins, H, Saleheen, D, Morris, A P, Colhoun, H M, Groop, L, Mccarthy, M I, Palmer, C N A, Danesh, J, Erdmann, J, Gu, D, Kooner, J S, Roberts, R, Schunkert, H, Assimes, T L, Blankenberg, S, Boehm, B O, Chambers, J C, Clarke, R, Collins, R, Dedoussis, G, Franks, P W, Hovingh, G K, Kim, B, Lehtimäki, T, Mcpherson, R, Nieminen, M S, O’donnell, C, Ripatti, S, Sandhu, M S, Schreiber, S, Siegbahn, A, Willer, C J, Zalloua, P A, Mark, M, Kanninen, T, Thorand, B, Remuzzi, G, Dunger, D, Shore, A, Smith, U, Groop, P, Ylä-herttuala, S, Cobelli, C, Bellazzi, R, Ferrannini, E, Patrono, C, Nuutila, P, Mckeague, P, Steckel-hamann, B, Gan, L, Nogoceke, E, Tortoli, P, Jablonka, B & Brosnan, M 2020, ' Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus ', Circulation: Genomic and precision medicine, vol. 13, no. 6 . https://doi.org/10.1161/CIRCGEN.119.002769
2020, ' Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus ', Circulation: Genomic and Precision Medicine, vol. 13, no. 6, pp. e002769 . https://doi.org/10.1161/CIRCGEN.119.002769
Circulation. Genomic and Precision Medicine
Circulation-Genomic and Precision Medicine, 13(6), 640-648. Lippincott Williams & Wilkins
Supplemental Digital Content is available in the text.
Background: Coronary artery disease (CAD) is accelerated in subjects with type 2 diabetes mellitus (T2D). Methods: To test whether this reflects differential genetic influences on CAD risk i
Background: Coronary artery disease (CAD) is accelerated in subjects with type 2 diabetes mellitus (T2D). Methods: To test whether this reflects differential genetic influences on CAD risk i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c110178bdcbf867d2320b1757655095
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=60858
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=60858
Autor:
Stéphanie Badiou, Christophe Normand, Yves Rinato, Timo Kanninen, Abdelhamid Barakat, Jean Frederic Brun, Florin Grigorescu, Jean-Marie Robine, Serghey Litvinov, Michel Pugeat, Ramon Gomis, Josep Maria Macias, Nicoleta Baculescu, Catalina Poiana, Carmen Emanuela Georgescu, Sara Haydar, Corin Badiu, Elza Khusnutdinova, Thibault Sutra, Yannick Cogne, Jacques Mercier, Renato Pasquali, Corinne Lautier, Saša Missoni, Dorina Ylli, Agron Ylli, Akila Zenati, Davide Lauro, Jean-Paul Cristol, Eric Renard, Agathocles Tsatsoulis, Monica Livia Gheorghiu, Giorgio Sesti, Sonia Abdelhak, Vincenzo Trischitta, Madalina Vintila, Yildiz Tutuncu, Ilhan Satman, Patrick Poucheret, Sabrina Prudente
Publikováno v:
PLoS ONE
PLoS ONE, Public Library of Science, 2019, 14 (3), pp.e0214122. ⟨10.1371/journal.pone.0214122⟩
RECERCAT (Dipòsit de la Recerca de Catalunya)
Recercat. Dipósit de la Recerca de Catalunya
instname
PLoS ONE, 2019, 14 (3), pp.e0214122. ⟨10.1371/journal.pone.0214122⟩
PLoS ONE, Vol 14, Iss 3, p e0214122 (2019)
PLoS ONE, Public Library of Science, 2019, 14 (3), pp.e0214122. ⟨10.1371/journal.pone.0214122⟩
RECERCAT (Dipòsit de la Recerca de Catalunya)
Recercat. Dipósit de la Recerca de Catalunya
instname
PLoS ONE, 2019, 14 (3), pp.e0214122. ⟨10.1371/journal.pone.0214122⟩
PLoS ONE, Vol 14, Iss 3, p e0214122 (2019)
International audience; Branched chain amino acids (BCAA) are essential elements of the human diet, which display increased plasma levels in obesity and regained particular interest as potential biomarkers for development of diabetes. To define deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfd5c6175733d01570e1df2a955f84d2
https://hal.archives-ouvertes.fr/hal-02080935
https://hal.archives-ouvertes.fr/hal-02080935
Biotechnology industry research produces a huge volume of data, and the amount doubles every few months. That is why data management requires sophisticated tools. This can be implemented in cooperation between public biological data infrastructures,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be4d9063c406c8424b9a6198a675758
Autor:
Tuomo Rankinen, Sheila A. Fisher, Daniel Levy, Steven C. Hunt, Cathryn M. Lewis, Markus Perola, Timo Kanninen, Fredrik von Wowern, Treva Rice, Sharon L.R. Kardia, Dabeeru C. Rao, Olle Melander, Liisa Koivukoski, Bonnie Thiel
Publikováno v:
Human Molecular Genetics. 13:2325-2332
Individual genome-wide scans of blood pressure (BP) and hypertension (HT) have shown inconsistent results. The aim of this study was to investigate whether there was any consistent evidence of linkage across multiple studies with similar ethnicity. W
Autor:
Fredrik von Wowern, Marju Orho-Melander, Lennart Råstam, Frej Fyhrquist, Philippe Burri, Kristina Bengtsson, Peter Almgren, Per Katzman, Carol Forsblom, Ulf Lindblad, Leif Groop, Olle Melander, Cecilia M. Lindgren, Timo Kanninen, U. Lennart Hulthén
Publikováno v:
Human Molecular Genetics. 12:2077-2081
With the aim of identifying hypertension susceptibility loci, we performed a genome wide scan in Scandinavian sib-pairs with early onset primary hypertension. To be classified as affected, a diagnosis of primary hypertension at age /= 1.0) were fine
Autor:
Alison Brown, Angels Costa, James L. Mills, Michael P. Bulman, Francesco Prisco, Sian Ellard, Timo Kanninen, Youxiang Wang, Yamina Benmezroua, Julie Evans, R Wright-Pascoe, Jean Claude Chevre, Torben Hansen, Pamidghantam Subba Rao, Oluf Pedersen, Martine Vaxillaire, Stephan Menzel, Ignacio Cognet, Peter Almgren, Melanie M. Mahtani, Timothy M. Frayling, Leif Groop, Christian Dina, Tiinamaija Tuomi, Marie Wishart, Cécile Lecoeur, Andrew T. Hattersley, Philippe Froguel, Cecilia M. Lindgren
Publikováno v:
University of Copenhagen
Maturity-onset diabetes of the young (MODY) is a heterogeneous single gene disorder characterized by non–insulin-dependent diabetes, an early onset and autosomal dominant inheritance. Mutations in six genes have been shown to cause MODY. Approximat
Autor:
Jianping Weng, Cecilia M. Lindgren, Peter Almgren, Haiyan Li, Olle Melander, Tiinamaija Tuomi, Elisabeth Widen, Markku Lehto, Leif Groop, Timo Kanninen
Publikováno v:
Diabetes. 51:1609-1617
In an attempt to identify novel susceptibility genes predisposing to early-onset diabetes (EOD), we performed a genome-wide scan using 433 markers in 222 individuals (119 with diabetes) from 29 Scandinavian families with ≥2 members with onset of di