N-truncated Aβ4–x peptides in sporadic Alzheimer’s disease cases and transgenic Alzheimer mouse models

Autor: Oliver Wirths, Susanne Walter, Inga Kraus, Hans W. Klafki, Martina Stazi, Timo J. Oberstein, Jorge Ghiso, Jens Wiltfang, Thomas A. Bayer, Sascha Weggen

Publikováno v: Alzheimer’s Research & Therapy, Vol 9, Iss 1, Pp 1-12 (2017)

Abstract Background The deposition of neurotoxic amyloid-β (Aβ) peptides in plaques in the brain parenchyma and in cerebral blood vessels is considered to be a key event in Alzheimer’s disease (AD) pathogenesis. Although the presence and impact o

Externí odkaz: https://doaj.org/article/6e0a0a2d6bb24114a8fa3fc6fcb54b8a

Development and Technical Validation of an Immunoassay for the Detection of APP669–711 (Aβ−3–40) in Biological Samples.

Autor: Klafki, Hans W.¹ (AUTHOR) hans.klafki@med.uni-goettingen.de, Rieper, Petra¹ (AUTHOR) silvia.zampar@med.uni-goettingen.de, Matzen, Anja² (AUTHOR) Anja.Matzen@tecan.com, Zampar, Silvia¹ (AUTHOR) oliver.wirths@medizin.uni-goettingen.de, Wirths, Oliver¹ (AUTHOR) jonathan.vogelgsang@med.uni-goettingen.de, Vogelgsang, Jonathan¹ (AUTHOR) lara.rohdenburg@stud.uni-goettingen.de, Osterloh, Dirk³ (AUTHOR) dirk.osterloh@roboscreen.com, Rohdenburg, Lara¹ (AUTHOR) Jens.Wiltfang@med.uni-goettingen.de, Oberstein, Timo J.⁴ (AUTHOR) Timo.Oberstein@uk-erlangen.de, Jahn, Olaf⁵ (AUTHOR) jahn@em.mpg.de, Beyer, Isaak⁶ (AUTHOR) isaak.beyer@web.de, Lachmann, Ingolf³ (AUTHOR) ingolf.lachmann@roboscreen.com, Knölker, Hans-Joachim⁶ (AUTHOR) hans-joachim.knoelker@tu-dresden.de, Wiltfang, Jens^1,7,8 (AUTHOR)

Publikováno v: International Journal of Molecular Sciences. Sep2020, Vol. 21 Issue 18, p6564-6564. 1p.