Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Timo Gemoll"'
Autor:
Franz F. Dressler, Falk Diedrichs, Deema Sabtan, Sofie Hinrichs, Christoph Krisp, Timo Gemoll, Martin Hennig, Paulina Mackedanz, Mareile Schlotfeldt, Hannah Voß, Anne Offermann, Jutta Kirfel, Marie C. Roesch, Julian P. Struck, Mario W. Kramer, Axel S. Merseburger, Christian Gratzke, Dominik S. Schoeb, Arkadiusz Miernik, Hartmut Schlüter, Ulrich Wetterauer, Roman Zubarev, Sven Perner, Philipp Wolf, Ákos Végvári
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Urothelial bladder cancer (UC) has a wide tumor biological spectrum with challenging prognostic stratification and relevant therapy-associated morbidity. Most molecular classifications relate only indirectly to the therapeutically relevant p
Externí odkaz:
https://doaj.org/article/5134170881c84f2485111eb97cd4a685
Autor:
Vijay Kumar Boddu, Piet Zamzow, Mario Wolfgang Kramer, Axel S. Merseburger, Sivahari Prasad Gorantla, Matthias Klinger, Lena Cramer, Thorben Sauer, Timo Gemoll, Nikolas von Bubnoff, Frank Gieseler, Masoud Darabi
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Extracellular vesicles (EVs), including microvesicles, hold promise for the management of bladder urothelial carcinoma (BLCA), particularly because of their utility in identifying therapeutic targets and their diagnostic potential
Externí odkaz:
https://doaj.org/article/27968117661440eb98397edea6f0a8e7
Autor:
Helen Pasternack, Mirjam Polzer, Timo Gemoll, Christiane Kümpers, Thorben Sauer, Pamela Lazar-Karsten, Sofie Hinrichs, Sabine Bohnet, Sven Perner, Franz Friedrich Dressler, Jutta Kirfel
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Lung cancer is the leading cause of cancer-related deaths worldwide with lung adenocarcinoma (LUAD) being the most common type. Genomic studies of LUAD have advanced our understanding of its tumor biology and accelerated targeted therapy. Ho
Externí odkaz:
https://doaj.org/article/09d107fdcd3c4d4cba2df94ebd3ea219
Autor:
Friederike Praus, Axel Künstner, Thorben Sauer, Michael Kohl, Katharina Kern, Steffen Deichmann, Ákos Végvári, Tobias Keck, Hauke Busch, Jens K. Habermann, Timo Gemoll
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Colorectal cancer (CRC) is one of the most prevalent cancers, with over one million new cases per year. Overall, prognosis of CRC largely depends on the disease stage and metastatic status. As precision oncology for patients with
Externí odkaz:
https://doaj.org/article/a3b31ca7db6f42b1a6ed7d76b3f8c000
Autor:
Benedikt Färber, Olga Lapshyna, Axel Künstner, Michael Kohl, Thorben Sauer, Kira Bichmann, Benjamin Heckelmann, Jessica Watzelt, Kim Honselmann, Louisa Bolm, Meike ten Winkel, Hauke Busch, Hendrik Ungefroren, Tobias Keck, Timo Gemoll, Ulrich F. Wellner, Rüdiger Braun
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
PurposeChemotherapy is pivotal in the multimodal treatment of pancreatic ductal adenocarcinoma (PDAC). Technical advances unveiled a high degree of inter- and intratumoral heterogeneity. We hypothesized that intratumoral heterogeneity (ITH) impacts r
Externí odkaz:
https://doaj.org/article/f332737a1dce4103ad86d6bd40b36538
Autor:
Nourhane Ammar, Maya Hildebrandt, Claudia Geismann, Christian Röder, Timo Gemoll, Susanne Sebens, Ania Trauzold, Heiner Schäfer
Publikováno v:
Antioxidants, Vol 12, Iss 10, p 1818 (2023)
Metabolic compartmentalization of stroma-rich tumors, like pancreatic ductal adenocarcinoma (PDAC), greatly contributes to malignancy. This involves cancer cells importing lactate from the microenvironment (reverse Warburg cells) through monocarboxyl
Externí odkaz:
https://doaj.org/article/3f337b46b0c8422fa790dcd023bbceb6
Autor:
Christoph Dumke, Timo Gemoll, Martina Oberländer, Sandra Freitag-Wolf, Christoph Thorns, Axel Glaessgen, Rinse Klooster, Silvère M. van der Maarel, Jerker Widengren, Christian Doehn, Gert Auer, Jens K. Habermann
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Current prostate cancer risk classifications rely on clinicopathological parameters resulting in uncertainties for prognostication. To improve individual risk stratification, we examined the predictive value of selected proteins with respect
Externí odkaz:
https://doaj.org/article/68a3591cd68b4f21a9b0964e6eb15294
Autor:
Timo Gemoll, Elena Miroll, Oliver Klein, Annette Lischka, Murat Eravci, Christoph Thorns, Jens K. Habermann
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background One major hallmark of colorectal cancers (CRC) is genomic instability with its contribution to tumor heterogeneity and therapy resistance. To facilitate the investigation of intra-sample phenotypes and the de novo identification o
Externí odkaz:
https://doaj.org/article/e178032f73024c6dbda38eec43effe97
Autor:
Rüdiger Braun, Scott Ronquist, Darawalee Wangsa, Haiming Chen, Lena Anthuber, Timo Gemoll, Danny Wangsa, Vishal Koparde, Cynthia Hunn, Jens K. Habermann, Kerstin Heselmeyer-Haddad, Indika Rajapakse, Thomas Ried
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 4, Pp 401-412 (2019)
Chromosomal aneuploidy is a defining feature of carcinomas and results in tumor-entity specific genomic imbalances. For instance, most sporadic colorectal carcinomas carry extra copies of chromosome 7, an aneuploidy that emerges already in premaligna
Externí odkaz:
https://doaj.org/article/35d0a8085ffe429fa3c4e14eb3f33649
Autor:
Peter Lamprecht, Anja Kerstein, Sebastian Klapa, Susanne Schinke, Christian M. Karsten, Xinhua Yu, Marc Ehlers, Jörg T. Epplen, Konstanze Holl-Ulrich, Thorsten Wiech, Kathrin Kalies, Tanja Lange, Martin Laudien, Tamas Laskay, Timo Gemoll, Udo Schumacher, Sebastian Ullrich, Hauke Busch, Saleh Ibrahim, Nicole Fischer, Katrin Hasselbacher, Ralph Pries, Frank Petersen, Gesche Weppner, Rudolf Manz, Jens Y. Humrich, Relana Nieberding, Gabriela Riemekasten, Antje Müller
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Anti-neutrophil cytoplasmic autoantibodies (ANCA) targeting proteinase 3 (PR3) and myeloperoxidase expressed by innate immune cells (neutrophils and monocytes) are salient diagnostic and pathogenic features of small vessel vasculitis, comprising gran
Externí odkaz:
https://doaj.org/article/3c4143f1c46040ea99bc33548a389fea