Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Timo Effenberger"'
Autor:
Timo Effenberger, Michel Riese, Nina Hedeman, Mohammad Shomali, Joachim Grötzinger, Inken Lorenzen, Ahmad Trad
Publikováno v:
International Journal of Oncology. 42:1793-1800
The malignant phenotype of carcinoma cells depends on their ability to invade into their microenvironment promoting metastasis. Therefore, carcinoma cells overexpress many proteins, including A disintegrin and metalloproteases (ADAMs). ADAM17 is expr
Autor:
Jan Sommer, Timo Effenberger, Elena Volpi, Georg H. Waetzig, Marten Bernhardt, Jan Suthaus, Christoph Garbers, Stefan Rose-John, Doreen M. Floss, Jürgen Scheller
Publikováno v:
Journal of Biological Chemistry. 287:13743-13751
Ligand-independent constitutively active gp130 mutants were described to be responsible for the development of inflammatory hepatocellular adenomas (IHCAs). These variants had gain-of-function somatic mutations within the extracellular domain 2 (D2)
Publikováno v:
European Respiratory Journal. 52:1800703
This review provides an overview of the role of long-term treatment of severe asthma with oral corticosteroids (OCS) and its associated side-effects in adults. It is based on a systematic literature search conducted in MEDLINE, Embase and the Cochran
Autor:
Christoph Garbers, Timo Effenberger, Björn Rabe, Stefan Rose-John, Gillian Murphy, Athena Chalaris, Kareen Bartsch, Jan von der Heyde, Klaus Schulze-Osthoff
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28(11)
Cellular senescence, a state of persistent cell cycle arrest, has emerged as a potent tumor suppressor mechanism by restricting proliferation of cells at risk for neoplastic transformation. Senescent cells secrete various growth factors, cytokines, a
Autor:
Björn Rabe, Timo Effenberger, Stefan Rose-John, Athena Chalaris, Kareen Bartsch, Jan von der Heyde
Publikováno v:
Cytokine. 63:261
Senescence is the irreversible growth arrest following cellular stressors such as DNA damage. It has become increasingly apparent that senescence represents a crucial tumor suppressor mechanism restricting the proliferation of cells at risk for neopl