International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes

Autor: Aldert H. Piersma, Rex E. FitzGerald, Manuela Tiramani, Florianne Monnet-Tschudi, Helena T. Hogberg, Gabriele Schmuck, Ellen Fritsche, Anna Bal-Price, Sandra Allen, Marcel Leist, Nathalie Delrue, Thomas Hartung, Martin Paparella, Daniela Maria Oggier, Timo Ylikomi, Timo Buetler, Eva Rached, Walter Lichtensteiger, Benoît Schilter, Susanne Hougaard Bennekou, Marta Axelstad, Michael Arand, Kevin M. Crofton, Martin F. Wilks, Tuula Heinonen, Luc Stoppini, Enrico Tongiorgi

Publikováno v: Bal-Price, A, Crofton, K M, Leist, M, Allen, S, Arand, M, Buetler, T, Delrue, N, FitzGerald, R E, Hartung, T, Heinonen, T, Hogberg, H, Bennekou, S H, Lichtensteiger, W, Oggier, D, Paparella, M, Petersen, M A, Piersma, A, Rached, E, Schilter, B, Schmuck, G, Stoppini, L, Tongiorgi, E, Tiramani, M, Monnet-Tschudi, F, Wilks, M F, Ylikomi, T & Fritsche, E 2015, ' International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes ', Archives of Toxicology, vol. 89, no. 2, pp. 269-287 . https://doi.org/10.1007/s00204-015-1464-2
Archives of Toxicology, vol. 89, no. 2, pp. 269-287
Archives of Toxicology

A major problem in developmental neurotoxicity (DNT) risk assessment is the lack of toxicological hazard information for most compounds. Therefore, new approaches are being considered to provide adequate experimental data that allow regulatory decisi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5930c858834c129b367351d4e39bee46
https://doi.org/10.1007/s00204-015-1464-2

The health risks of dietary advanced glycation end-products

Autor: Timo Buetler

Publikováno v: Molecular Nutrition & Food Research. 51:1071-1073

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f1ad4d0c2cc1b3eb0fc63863ac3931b3
https://doi.org/10.1002/mnfr.200790017

Dietary factors and low-grade inflammation in relation to overweight and obesity

Autor: Ascensión Marcos, Namanjeet Ahluwalia, Andrew N. Margioris, Casper G. Schalkwijk, Herve Nordmann, Lena S. Jönsson, Timo Buetler, Julia Wärnberg, Nathan V. Matusheski, Salwa W. Rizkalla, John O’Brien, Karen Cunningham, Fred Brouns, Hubert Kolb, Giuseppe Pugliese, Katherine Esposito, Jaakko Tuomilehto, Brigitte M. Winklhofer-Roob, Karine Clément, Bernhard Watzl, Philip C. Calder, Mirian Lansink

Publikováno v: British Journal of Nutrition, 106(S3), S5-S78. Cambridge University Press
Scopus-Elsevier

Low-grade inflammation is a characteristic of the obese state, and adipose tissue releases many inflammatory mediators. The source of these mediators within adipose tissue is not clear, but infiltrating macrophages seem to be especially important, al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6938e835ce628ba90111942d268867a7
https://cris.maastrichtuniversity.nl/en/publications/0d1fa066-0e8f-40b1-b3a7-5f41b876f50c

Analysis of advanced glycation endproducts in dairy products by isotope dilution liquid chromatography-electrospray tandem mass spectrometry. The particular case of carboxymethyllysine

Autor: Jörg Hegele, Janique Richoz, Véronique Parisod, Sarah Maurer, Matthew David Steven, Thierry Delatour, Timo Buetler

Publikováno v: Journal of chromatography. A. 1216(12)

A fully validated multiple-transition recording isotope dilution liquid chromatography-electrospray tandem mass spectrometry (LC-MS/MS) method for the simultaneous quantitative determination of N(epsilon)-carboxymethyllysine (CML) and lysine in dairy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f8d18d6c3236a94080bc6e4873600b
https://pubmed.ncbi.nlm.nih.gov/19181321

Dicarbonyls stimulate cellular protection systems in primary rat hepatocytes and show anti-inflammatory properties

Autor: Thierry Delatour, Timo Buetler, Hélia Latado, Alexandra Baumeyer

Publikováno v: Annals of the New York Academy of Sciences. 1126

Advanced glycation endproducts (AGEs) and their precursor dicarbonyls are generally perceived as having adverse health effects. They are also considered to be initiators and promoters of disease and aging. However, proof for a causal relationship is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5654ab8af69fe7a7c1e7d8a5317a0ef0
https://pubmed.ncbi.nlm.nih.gov/18448803