Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Timo Bragge"'
Autor:
Karen Lariosa-Willingham, Dmitri Leonoudakis, Timo Bragge, Laura Tolppanen, Antti Nurmi, Megan Flanagan, Janelle Gibson, David Wilson, Jennifer Stratton, Kimmo K. Lehtimäki, Diana Miszczuk
Publikováno v:
BMC Neuroscience, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background Therapeutic agents stimulating the process of myelination could be beneficial for the treatment of demyelinating diseases, such as multiple sclerosis. The efficient translation of compounds promoting myelination in vitro to effica
Externí odkaz:
https://doaj.org/article/6a43bef6c05a44c498bd5a3f3b1919a9
Autor:
Taneli Heikkinen, Timo Bragge, Juha Kuosmanen, Teija Parkkari, Sanna Gustafsson, Mei Kwan, Jose Beltran, Afshin Ghavami, Srinivasa Subramaniam, Neelam Shahani, Uri Nimrod Ramírez-Jarquín, Larry Park, Ignacio Muñoz-Sanjuán, Deanna M Marchionini
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0258486 (2021)
Huntington's disease (HD) results from an expansion mutation in the polyglutamine tract in huntingtin. Although huntingtin is ubiquitously expressed in the body, the striatum suffers the most severe pathology. Rhes is a Ras-related small GTP-binding
Externí odkaz:
https://doaj.org/article/5d08393a3e9247bea54802339f2736c8
Rapid and robust patterns of spontaneous locomotor deficits in mouse models of Huntington's disease.
Autor:
Taneli Heikkinen, Timo Bragge, Niina Bhattarai, Teija Parkkari, Jukka Puoliväli, Outi Kontkanen, Patrick Sweeney, Larry C Park, Ignacio Munoz-Sanjuan
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243052 (2020)
Huntington's disease (HD) is an inherited neurodegenerative disorder characterized by severe disruption of cognitive and motor functions, including changes in posture and gait. A number of HD mouse models have been engineered that display behavioral
Externí odkaz:
https://doaj.org/article/07aa52b632ac417abd3cbd33a4065cef
Autor:
Alper Yavas, Rudie Weij, Maaike van Putten, Eleni Kourkouta, Chantal Beekman, Jukka Puoliväli, Timo Bragge, Toni Ahtoniemi, Jeroen Knijnenburg, Marlies Elisabeth Hoogenboom, Yavuz Ariyurek, Annemieke Aartsma-Rus, Judith van Deutekom, Nicole Datson
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0244215 (2020)
Duchenne muscular dystrophy (DMD) is a severe, progressive neuromuscular disorder caused by reading frame disrupting mutations in the DMD gene leading to absence of functional dystrophin. Antisense oligonucleotide (AON)-mediated exon skipping is a th
Externí odkaz:
https://doaj.org/article/77187c115727491f8d71a4bd11be5bd2
Autor:
Jay A. Berzofsky, Lauren Gerard Koch, Steven L. Britton, Shaochen Chen, Wei Zhu, Xuanyi Ma, Anthony G. Comuzzie, Laetitia Devy-Dimanche, Ryan Feaver, Jan Grimm, Christoph Hock, Roger M. Nitsch, James B. Hoying, Aldons J. Lusis, Francesco Marincola, Josue Samayoa, Tolga Turan, David A. Pearce, Antti Nurmi, Tuulia Huhtala, Artem Shatillo, Jukka Puoliväli, Taneli Heikkinen, Timo Bragge, Kimmo Lehtimäki, Arun J. Sanyal, Kevin Strange, D. Lansing Taylor, Mark Miedel, Shanhang Jia, Alex Soto-Guterriez, Andrew Stern, Albert Gough
Publikováno v:
Journal of Translational Medicine, Vol 15, Iss S3, Pp 1-7 (2017)
Externí odkaz:
https://doaj.org/article/495726c749064892a0b63dd7bba85d72
Autor:
Judith van Deutekom, Chantal Beekman, Suzanne Bijl, Sieto Bosgra, Rani van den Eijnde, Dennis Franken, Bas Groenendaal, Bouchra Harquouli, Anneke Janson, Paul Koevoets, Melissa Mulder, Daan Muilwijk, Galyna Peterburgska, Bianca Querido, Janwillem Testerink, Ruurd Verheul, Peter de Visser, Rudie Weij, Annemieke Aartsma-Rus, Jukka Puoliväli, Timo Bragge, Charles O'Neill, Nicole A. Datson
Publikováno v:
Nucleic Acid Therapeutics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c189efe6f501e93d50dd9a15beb55118
https://doi.org/10.1089/nat.2022.0063
https://doi.org/10.1089/nat.2022.0063
Autor:
Karen Lariosa-Willingham, Dmitri Leonoudakis, Timo Bragge, Laura Tolppanen, Antti Nurmi, Megan Flanagan, Janelle Gibson, David Wilson, Jennifer Stratton, Kimmo K. Lehtimäki, Diana Miszczuk
Publikováno v:
BMC neuroscience. 23(1)
Background Therapeutic agents stimulating the process of myelination could be beneficial for the treatment of demyelinating diseases, such as multiple sclerosis. The efficient translation of compounds promoting myelination in vitro to efficacy in viv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::787a417064a7182cd463ec66ee42f93b
https://pubmed.ncbi.nlm.nih.gov/35614392
https://pubmed.ncbi.nlm.nih.gov/35614392
Autor:
Jose Beltran, Teija Parkkari, Sanna Gustafsson, Neelam Shahani, Afshin Ghavami, Larry Park, Taneli Heikkinen, Mei Kwan, Deanna Marchionini, Srinivasa Subramaniam, Juha Kuosmanen, Uri Nimrod Ramírez-Jarquín, Timo Bragge, Ignacio Munoz-Sanjuan
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 10, p e0258486 (2021)
PLoS ONE, Vol 16, Iss 10, p e0258486 (2021)
Huntington’s disease (HD) results from an expansion mutation in the polyglutamine tract in huntingtin. Although huntingtin is ubiquitously expressed in the body, the striatum suffers the most severe pathology. Rhes is a Ras-related small GTP-bindin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6878ef4acd983462325493f313aadebc
https://pubmed.ncbi.nlm.nih.gov/34648564
https://pubmed.ncbi.nlm.nih.gov/34648564
Autor:
Eleni Kourkouta, Maaike van Putten, Annemieke Aartsma-Rus, Toni Ahtoniemi, Yavuz Ariyurek, Chantal Beekman, Timo Bragge, Alper Yavas, Marlies Elisabeth Hoogenboom, Rudie Weij, Nicole A. Datson, Jeroen Knijnenburg, Jukka Puoliväli, Judith C.T. van Deutekom
Publikováno v:
PLoS ONE, 15(12). PUBLIC LIBRARY SCIENCE
PLoS ONE
PLoS ONE, Vol 15, Iss 12, p e0244215 (2020)
PLoS ONE
PLoS ONE, Vol 15, Iss 12, p e0244215 (2020)
Duchenne muscular dystrophy (DMD) is a severe, progressive neuromuscular disorder caused by reading frame disrupting mutations in the DMD gene leading to absence of functional dystrophin. Antisense oligonucleotide (AON)-mediated exon skipping is a th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7764ad068b51e1bc78f949eac1a31f41
http://hdl.handle.net/1887/3184630
http://hdl.handle.net/1887/3184630
Autor:
Rani van den Eijnde, Jukka Puoliväli, Anneke A.M. Janson, Toni Ahtoniemi, Janwillem Testerink, Nicole A. Datson, Kimmo Lehtimäki, Suzanne Bijl, Judith C.T. van Deutekom, Rudie Weij, Timo Bragge
Publikováno v:
Nucleic Acid Therapeutics
Duchenne muscular dystrophy (DMD) is a severe childhood muscle disease primarily caused by the lack of functional dystrophin at the muscle fiber membranes. Multiple therapeutic approaches are currently in (pre)clinical development, aimed at restoring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84f2b225baf73b85e079edc2c98b361c
https://pubmed.ncbi.nlm.nih.gov/31821107
https://pubmed.ncbi.nlm.nih.gov/31821107