Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Timo, Kirschstein"'
Autor:
Falko Lange, Richard Gade, Anne Einsle, Katrin Porath, Gesine Reichart, Claudia Maletzki, Björn Schneider, Christian Henker, Daniel Dubinski, Michael Linnebacher, Rüdiger Köhling, Thomas M. Freiman, Timo Kirschstein
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundThe differentiation of high-grade glioma and brain tumors of an extracranial origin is eminent for the decision on subsequent treatment regimens. While in high-grade glioma, a surgical resection of the tumor mass is a fundamental part of cu
Externí odkaz:
https://doaj.org/article/dbe6cf8eeb524090a81b93767e6a50e6
Publikováno v:
Brain Sciences, Vol 14, Iss 6, p 603 (2024)
High-frequency magnetic stimulation (HFMS) applied directly to the hippocampal slice preparation in vitro induces activity-dependent synaptic plasticity and metaplasticity. In addition, changes in synaptic transmission following HFMS involve the acti
Externí odkaz:
https://doaj.org/article/50cef6655de249608b80d41dcec44792
Autor:
Timo Kirschstein, Rüdiger Köhling
Publikováno v:
Neurobiology of Disease, Vol 184, Iss , Pp 106221- (2023)
Autoimmune-mediated encephalitis syndromes are increasingly being recognized as important clinical entities. They need to be thought of as differential diagnosis in any patient presenting with fast-onset psychosis or psychiatric problems, memory defi
Externí odkaz:
https://doaj.org/article/cfd18c145e5649bb92d5d45da689309c
Autor:
Elisabeth Schültke, Michael Lerch, Timo Kirschstein, Falko Lange, Katrin Porath, Stefan Fiedler, Jeremy Davis, Jason Paino, Elette Engels, Micah Barnes, Mitzi Klein, Christopher Hall, Daniel Häusermann, Guido Hildebrandt
Publikováno v:
Journal of Synchrotron Radiation, Vol 29, Iss 4, Pp 1027-1032 (2022)
Microbeam radiotherapy could help to cure malignant tumours which are currently still considered therapy-resistant. With an irradiation target in the thoracic cavity, the heart would be one of the most important organs at risk. To assess the acute ad
Externí odkaz:
https://doaj.org/article/7c4f0d17d2424fabbc38e89c641ee115
Autor:
Falko Lange, Katrin Porath, Tina Sellmann, Anne Einsle, Robert Jaster, Michael Linnebacher, Rüdiger Köhling, Timo Kirschstein
Publikováno v:
Biology, Vol 12, Iss 7, p 1032 (2023)
Several cues for a directional migration of colorectal cancer cells were identified as being crucial in tumor progression. However, galvanotaxis, the directional migration in direct-current electrical fields, has not been investigated so far. Therefo
Externí odkaz:
https://doaj.org/article/b33524b735304477832211c4cfb216e8
Autor:
Bernd Frerker, Stefan Fiedler, Timo Kirschstein, Falko Lange, Katrin Porath, Tina Sellmann, Leonie Kutzner, Fabian Wilde, Julian Moosmann, Rüdiger Köhling, Guido Hildebrandt, Elisabeth Schültke
Publikováno v:
Cells, Vol 12, Iss 1, p 176 (2022)
Background: High-dose-rate radiotherapy has shown promising results with respect to normal tissue preservation. We developed an ex vivo model to study the physiological effects of experimental radiotherapy in the rodent esophageal smooth muscle. Meth
Externí odkaz:
https://doaj.org/article/8710f0122d5c499786b0045983c125aa
Autor:
Julia Hörnschemeyer, Timo Kirschstein, Gesine Reichart, Christin Sasse, Jakob Venus, Anne Einsle, Katrin Porath, Michael Linnebacher, Rüdiger Köhling, Falko Lange
Publikováno v:
Life, Vol 12, Iss 8, p 1258 (2022)
Glioblastoma is the most common and aggressive primary brain tumor. Multiple genetic and epigenetic alterations in several major signaling pathways—including the phosphoinositide 3-kinases (PI3K)/AKT/mTOR and the Raf/MEK/ERK pathway—could be foun
Externí odkaz:
https://doaj.org/article/64c574a36cb848dcad686160cd9bb2c5
Autor:
Falko Lange, Jakob Venus, Daria Shams Esfand Abady, Katrin Porath, Anne Einsle, Tina Sellmann, Valentin Neubert, Gesine Reichart, Michael Linnebacher, Rüdiger Köhling, Timo Kirschstein
Publikováno v:
Life, Vol 12, Iss 4, p 580 (2022)
Galvanotaxis, the migration along direct current electrical fields, may contribute to the invasion of brain cancer cells in the tumor-surrounding tissue. We hypothesized that pharmacological perturbation of the epidermal growth factor (EGF) receptor
Externí odkaz:
https://doaj.org/article/97991a2cd81741d8b0ff5b05fb017a33
Autor:
Falko Lange, Jens Hartung, Clara Liebelt, Julius Boisserée, Tobias Resch, Katrin Porath, Max Frederik Hörnschemeyer, Gesine Reichart, Tina Sellmann, Valentin Neubert, Stephan Kriesen, Guido Hildebrandt, Elisabeth Schültke, Rüdiger Köhling, Timo Kirschstein
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
An abnormal glutamate signaling of glioblastoma may contribute to both tumor progression and the generation of glioma-associated epileptic seizures. We hypothesized that the AMPA receptor antagonist perampanel (PER) could attenuate tumor growth and e
Externí odkaz:
https://doaj.org/article/766c75cc8c414ac6959b68edd833ce6e
Autor:
Timo Kirschstein, Erika Sadkiewicz, Gerda Hund-Göschel, Juliane Becker, Xiati Guli, Steffen Müller, Marco Rohde, Dora-Charlotte Hübner, Hannes Brehme, Stephan Kolbaske, Katrin Porath, Tina Sellmann, Annette Großmann, Matthias Wittstock, Steffen Syrbe, Alexander Storch, Rüdiger Köhling
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 12 (2020)
PurposeWe present a case of voltage-gated potassium channel (VGKC) complex antibody-positive limbic encephalitis (LE) harboring autoantibodies against Kv1.2. Since the patient responded well to immunotherapy, the autoantibodies were regarded as patho
Externí odkaz:
https://doaj.org/article/c2833c7d44c24ad8a9270b2b7c640387