Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Timmy Le"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Drug use poses a serious threat to health systems throughout the world. The number of consumers rises every year being alcohol the drug of abuse most consumed causing 3 million deaths (5.3% of all deaths) worldwide and 132.6 million disability-adjust
Externí odkaz:
https://doaj.org/article/7fcc2fadd8dd46f0a6d4e54625c0d326
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Animals studies support the notion that striatal cholinergic interneurons (ChIs) play a central role in basal ganglia function by regulating associative learning, reward processing, and motor control. In the nucleus accumbens (NAc), a brain region th
Externí odkaz:
https://doaj.org/article/0186602a08c54709a50a43eda99f7d70
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Triplet-triplet annihilation upconversion (TTA-UC) nanoparticles (NPs) are a promising material for diverse applications, but TTA-UC is sensitive to oxygen, which hinders its biological utility. Here, the authors report an enzymatic method to deplete
Externí odkaz:
https://doaj.org/article/9311c175e758406fb50362d115bec847
Autor:
Timmy Le, Cynthia L Winham, Fotis Andromidas, Adam C Silver, Evan R Jellison, Aime A Levesque, Andrew O Koob
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 10, Pp 1894-1902 (2020)
Elevated levels of γ-synuclein (γ-syn) expression have been noted in the progression of glioblastomas, and also in the cerebrospinal fluid of patients diagnosed with neurodegenerative diseases. γ-Syn can be either internalized from the extracellul
Externí odkaz:
https://doaj.org/article/dae6b1066d5044bd94ec561d83ed1d82
Autor:
Jenya Kolpakova, Vincent van der Vinne, Pablo Giménez-Gómez, Timmy Le, In-Jee You, Rubing Zhao-Shea, Cristina Velazquez-Marrero, Andrew R. Tapper, Gilles E. Martin
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
The nucleus accumbens (NAc) is a forebrain region mediating the positive-reinforcing properties of drugs of abuse, including alcohol. It receives glutamatergic projections from multiple forebrain and limbic regions such as the prefrontal cortex (PFCx
Externí odkaz:
https://doaj.org/article/dd30f11b35e446e496adf5807da19d95
Specific Neuroligin3–αNeurexin1 signaling regulates GABAergic synaptic function in mouse hippocampus
Autor:
Motokazu Uchigashima, Kohtarou Konno, Emily Demchak, Amy Cheung, Takuya Watanabe, David G Keener, Manabu Abe, Timmy Le, Kenji Sakimura, Toshikuni Sasaoka, Takeshi Uemura, Yuka Imamura Kawasawa, Masahiko Watanabe, Kensuke Futai
Publikováno v:
eLife, Vol 9 (2020)
Synapse formation and regulation require signaling interactions between pre- and postsynaptic proteins, notably cell adhesion molecules (CAMs). It has been proposed that the functions of neuroligins (Nlgns), postsynaptic CAMs, rely on the formation o
Externí odkaz:
https://doaj.org/article/8267cca0c2ad4e819a3495d720c4cf1d
Autor:
Andrew O Koob, Evan R. Jellison, Cynthia L. Winham, Adam C. Silver, Timmy Le, Fotis Andromidas, Aime A. Levesque
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 10, Pp 1894-1902 (2020)
Neural Regeneration Research
Neural Regeneration Research
Elevated levels of γ-synuclein (γ-syn) expression have been noted in the progression of glioblastomas, and also in the cerebrospinal fluid of patients diagnosed with neurodegenerative diseases. γ-Syn can be either internalized from the extracellul
Autor:
Gilles E. Martin, Andrew R. Tapper, Vincent van der Vinne, Pablo Giménez-Gómez, In-Jee You, Jenya Kolpakova, Cristina Velázquez-Marrero, Rubing Zhao-Shea, Timmy Le
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
The nucleus accumbens (NAc) is a forebrain region mediating the positive-reinforcing properties of drugs of abuse, including alcohol. It receives glutamatergic projections from multiple forebrain and limbic regions such as the prefrontal cortex (PFCx
Autor:
Aime A. Levesque, Evan R. Jellison, Cynthia L. Winham, Timmy Le, Andrew O Koob, Adam C. Silver
Publikováno v:
Neuroscience. 410:41-54
γ-Synuclein (γ-syn) is expressed by astrocytes in the human nervous system, and increased extracellularly in the brain and cerebrospinal fluid of individuals diagnosed with Alzheimer's disease. Upregulation of γ-syn also coincides with proliferati
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Triplet-triplet annihilation upconversion nanoparticles have attracted considerable interest due to their promises in organic chemistry, solar energy harvesting and several biological applications. However, triplet-triplet annihilation upconversion i