The circadian clock influences T cell responses to vaccination by regulating dendritic cell antigen processing.

Autor: Cervantes-Silva MP; Curtis Clock Laboratory, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland RCSI, Dublin, Ireland., Carroll RG; Curtis Clock Laboratory, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland RCSI, Dublin, Ireland., Wilk MM; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.; Department of Immunology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland., Moreira D; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Payet CA; Curtis Clock Laboratory, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland RCSI, Dublin, Ireland., O'Siorain JR; Curtis Clock Laboratory, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland RCSI, Dublin, Ireland., Cox SL; Curtis Clock Laboratory, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland RCSI, Dublin, Ireland., Fagan LE; Curtis Clock Laboratory, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland RCSI, Dublin, Ireland.; Tissue Engineering Research Group (TERG), Royal College of Surgeons in Ireland RCSI, Dublin, Ireland., Klavina PA; Curtis Clock Laboratory, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland RCSI, Dublin, Ireland.; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland RCSI, Dublin, Ireland., He Y; Curtis Clock Laboratory, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland RCSI, Dublin, Ireland.; Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou, China., Drewinski T; Curtis Clock Laboratory, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland RCSI, Dublin, Ireland., McGinley A; Curtis Clock Laboratory, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland RCSI, Dublin, Ireland., Buel SM; Department of Biological Sciences & Center for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA., Timmons GA; Curtis Clock Laboratory, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland RCSI, Dublin, Ireland., Early JO; Curtis Clock Laboratory, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland RCSI, Dublin, Ireland.; Tissue Engineering Research Group (TERG), Royal College of Surgeons in Ireland RCSI, Dublin, Ireland., Preston RJS; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland RCSI, Dublin, Ireland., Hurley JM; Department of Biological Sciences & Center for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, Troy, NY, 12180, USA., Finlay DK; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Schoen I; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland RCSI, Dublin, Ireland., Javier Sánchez-García F; Immunoregulation Laboratory, Department of Immunology, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, México City, Mexico., Mills KHG; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland., Curtis AM; Curtis Clock Laboratory, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland RCSI, Dublin, Ireland. anniecurtis@rcsi.com.; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland. anniecurtis@rcsi.com.; Tissue Engineering Research Group (TERG), Royal College of Surgeons in Ireland RCSI, Dublin, Ireland. anniecurtis@rcsi.com.; Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland RCSI, Dublin, Ireland. anniecurtis@rcsi.com.

Publikováno v: Nature communications [Nat Commun] 2022 Dec 05; Vol. 13 (1), pp. 7217. Date of Electronic Publication: 2022 Dec 05.

Post-transcriptional circadian regulation in macrophages organizes temporally distinct immunometabolic states.

Autor: Collins EJ; Department of Biological Sciences, Rensselaer Polytechnic Institute, Troy, New York 12180, USA., Cervantes-Silva MP; School of Pharmacy and Biomedical Sciences and Tissue Engineering Research Group, Royal College of Surgeons in Ireland, Dublin D02, Ireland., Timmons GA; School of Pharmacy and Biomedical Sciences and Tissue Engineering Research Group, Royal College of Surgeons in Ireland, Dublin D02, Ireland., O'Siorain JR; School of Pharmacy and Biomedical Sciences and Tissue Engineering Research Group, Royal College of Surgeons in Ireland, Dublin D02, Ireland., Curtis AM; School of Pharmacy and Biomedical Sciences and Tissue Engineering Research Group, Royal College of Surgeons in Ireland, Dublin D02, Ireland., Hurley JM; Department of Biological Sciences, Rensselaer Polytechnic Institute, Troy, New York 12180, USA.; Center for Biotechnology and Interdisciplinary Sciences, Rensselaer Polytechnic Institute, Troy, New York 12180, USA.

Publikováno v: Genome research [Genome Res] 2021 Feb; Vol. 31 (2), pp. 171-185. Date of Electronic Publication: 2021 Jan 12.

Immunometabolism around the Clock.

Autor: Carroll RG; Curtis Clock Laboratory, Molecular and Cellular Therapeutics Department, Royal College of Surgeons in Ireland (RCSI), Dublin 2, Ireland; Tissue Engineering Research Group, Department of Anatomy, Royal College of Surgeons in Ireland (RCSI), Dublin 2, Ireland; Advanced Materials Bio-Engineering Research (AMBER) Centre, Trinity College Dublin, Dublin 2, Ireland. Electronic address: richardcarroll@rcsi.com., Timmons GA; Curtis Clock Laboratory, Molecular and Cellular Therapeutics Department, Royal College of Surgeons in Ireland (RCSI), Dublin 2, Ireland; Tissue Engineering Research Group, Department of Anatomy, Royal College of Surgeons in Ireland (RCSI), Dublin 2, Ireland; Advanced Materials Bio-Engineering Research (AMBER) Centre, Trinity College Dublin, Dublin 2, Ireland., Cervantes-Silva MP; Curtis Clock Laboratory, Molecular and Cellular Therapeutics Department, Royal College of Surgeons in Ireland (RCSI), Dublin 2, Ireland; Tissue Engineering Research Group, Department of Anatomy, Royal College of Surgeons in Ireland (RCSI), Dublin 2, Ireland; Advanced Materials Bio-Engineering Research (AMBER) Centre, Trinity College Dublin, Dublin 2, Ireland., Kennedy OD; Tissue Engineering Research Group, Department of Anatomy, Royal College of Surgeons in Ireland (RCSI), Dublin 2, Ireland; Advanced Materials Bio-Engineering Research (AMBER) Centre, Trinity College Dublin, Dublin 2, Ireland., Curtis AM; Curtis Clock Laboratory, Molecular and Cellular Therapeutics Department, Royal College of Surgeons in Ireland (RCSI), Dublin 2, Ireland; Tissue Engineering Research Group, Department of Anatomy, Royal College of Surgeons in Ireland (RCSI), Dublin 2, Ireland; Advanced Materials Bio-Engineering Research (AMBER) Centre, Trinity College Dublin, Dublin 2, Ireland. Electronic address: anniecurtis@rcsi.com.

Publikováno v: Trends in molecular medicine [Trends Mol Med] 2019 Jul; Vol. 25 (7), pp. 612-625. Date of Electronic Publication: 2019 May 29.